263 research outputs found
Universality and correlations in individuals wandering through an online extremist space
The 'out of the blue' nature of recent terror attacks and the diversity of
apparent motives, highlight the importance of understanding the online
trajectories that individuals follow prior to developing high levels of
extremist support. Here we show that the physics of stochastic walks, with and
without temporal correlation, provides a unifying description of these online
trajectories. Our unique dataset comprising all users of a global social media
site, reveals universal characteristics in individuals' online lifetimes. Our
accompanying theory generates analytical and numerical solutions that describe
the characteristics shown by individuals that go on to develop high levels of
extremist support, and those that do not. The existence of these temporal and
also many-body correlations suggests that existing physics machinery can be
used to quantify and perhaps mitigate the risk of future events
Teenagersβ vandalism and the importance of parent-child relationships in addressing it
Vandalism in the urban environment is a common phenomenon but is difficult to evaluate. The scale of damage caused by vandalism is rarely analyzed, and therefore a limited number of scientific works are devoted to the phenomenon of vandal behavior and the identification of its causes. While the role of the family in the formation of deviant behavior is indicated by many researchers, the context of vandalism and the issue of family determination remains open. This article studies the parentsβ styles of upbringing and their preparation for teenagersβ vandal behavior. By identifying the degree of influence of the family in the formation of such a destructive form of interaction between teenagersβ and the material environment it is possible to identify a group of teenagers who are ready to commit acts of vandalism. An attempt is made to correlate child-parent relations with teenagersβ motivational readiness to commit acts of vandalism. To study the relationship of child-parent relations and teenagersβ vandal behavior, data was collected (using psycho-diagnostic techniques) from 60 teenagers and their parents from complete and incomplete families, the socially well-off and the socially disadvantaged. The results were processed using descriptive statistics, MANOVA and linear regression analysis. It was found that parental upbringing styles play a decisive role in initiating vandalism, while the educational effects of mother and father have their own specific characteristics. The results can be used in the organization of social support for children from socially disadvantaged families in order to prevent vandalism and its radicalization. Β© 2018, Kazan Federal University. All rights reserved
The role of the social vocabulary research in the Russian language teaching practice (on the example of zoomorphic nominations Homo Socialis)
The relevance of the investigated problem is stipulated by the necessity to solve a problem of multicultural humanitarian education and formation of tolerance of students to unfamiliar culture. The purpose of the article is to research educational potential of metaphorical vocabulary in different languages, such as zoomorphic naming units of a man in his social roles and functions. The leading approach to the study of this problem is a communicatively oriented approach to training highly qualified specialist, the future teacher of Russian as a foreign language or an interpreter. The study produced the following results: the possibility to use ethno-linguistic study of Russian language results is illustrated; a selection of lexical items and phraseologic- zoomorphism, which nominate people on the social roles and functions - tat teacher can use in the classroom, is presented; the technique of analysis of the vocabulary in which social seme is located in different zones of the word, is presented; the necessity of the use of research results in the practice of teaching in higher school in order to ensure the formation of socio-cultural and communicative competence of students is substantiated. The results can be applied in the organization of educational process in higher educational institutions. The article may be useful to researchers in the field of pedagogy, to teachers, to post-graduate students, to graduate students and students of the following specialties: Russian as a foreign language, Russian language in the practice of interpretation. Β© 2016 Leontyeva et al
Value of Safety of Anticoagulant Therapy in Elderly Patient with Atrial Fibrillation and High Risk of Bleeding
The review article discussesΒ the safety issue of anticoagulant therapy in elderly patients with atrial fibrillation and high risk of bleeding.Β An evidence base is presented demonstrating the high safety of rivaroxaban in patients over 80Β years of age,Β with a high risk of bleedingΒ and cardiovascular complications,Β the presence of comorbidΒ pathology, geriatric syndromesΒ and chronic kidney disease (including in combination with anemia). The problem of low adherence to treatment in elderly patients and the possibility of solving it were separately considered
Postinfectious syndrome of convalescentsixodes tick-borne borreliosis
The aim: to study the psycho-vegetative status of theΒ quantitative contents of serotonin in blood platelets in patientsΒ after the Ixodes tick-borne borreliosis, to evaluate theΒ clinical efficiency treatment by adamantilfenilamin of postinfectionΒ asthenia.Materials and methods: there was clinical supervisionΒ and inspection conducted of 118 convalescents borreliosisΒ after a course of inpatient treatment. All patients were examinedΒ using psychovegetative tests. Platelet serotonin concentrationΒ levels were measured by enzyme immunoassay. ForΒ the treatment of postinfectious asthenia 36 convalescentsΒ received adamantilbromfenilamin in a dose of 100 mg for 25Β days.Results: when tested convalescents marked change inΒ indicators of emotional and personality disorders. QuantitativeΒ study of blood platelet serotonin content revealed a significantΒ decrease in this indicator relative to control values.Β Study the correlations between obtained when testing theΒ psycho-emotional parameters and platelet serotonin levelsΒ showed a negative correlation between serotonin and an indicatorΒ of reactive anxiety (R = -0,81, p <0,05). To correctΒ these violations convalescents with severe asthenia postinfectionΒ were treated adamantilfenilamin. Established clinicalΒ efficacy contributing to the improvement of the qualityΒ of life.Conclusion: the research of neurotransmitter serotoninΒ in patients during the convalescence period after borreliosisΒ possible to evaluate the extent of potential damage to theΒ nervous tissue in the inflammatory process and its involvementΒ in the formation of anxiety and depressive symptoms.Β adamantilbromfenilamin can be recommended for rehabilitationΒ patients with residual effects in the form of postinfectiousΒ asthenia
Mechanisms of transcriptional regulation of ecdysone response
The mechanisms of ecdysone-dependent expression have been studied for many decades. Initially, the activation of individual genes under the influence of ecdysone was studied on the model of polythene chromosomes from salivary glands of Drosophila melanogaster. These works helped to investigate the many aspects of the Drosophila development. They also revealed plenty of valuable information regarding the fundamental mechanisms controlling the genesβ work. Many years ago, a model describing the process of gene activation by ecdysone, named after the author β Ashburner model β was proposed. This model is still considered an excellent description of the ecdysone cascade, which is implemented in the salivary glands during the formation of the Drosophila pupa. However, these days there is an opinion that the response of cells to the hormone ecdysone can develop with significant differences, depending on the type of cells. The same genes can be activated or repressed under the influence of ecdysone in different tissues. Likely, certain DNA-binding transcription factors that are involved in the ecdysonedependent response together with the EcR/Usp heterodimer are responsible for cell-type specificity. A number of transcriptional regulators involved in the ecdysone response have been described. Among them are several complexes responsible for chromatin remodeling and modification. It has been shown by various methods that ecdysone-dependent activation/repression of gene transcription develops with significant structural changes of chromatin on regulatory elements. The description of the molecular mechanism of this process, in particular, the role of individual proteins in it, as well as structural interactions between various regulatory elements is a matter of the future. This review is aimed to discuss the available information regarding the main regulators that interact with the ecdysone receptor. We provide a brief description of the regulatorβs participation in the ecdysone response and links to the corresponding study. We also discuss general aspects of the mechanism of ecdysone-dependent regulation and highlight the most promising points for further research
ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΡΠ΅Π½ΠΎΡΠΈΠΏΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΈ Π³Π΅Π½ΠΎΡΠΈΠΏΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π»ΠΈΠΏΠΈΠ΄Π½ΠΎΠ³ΠΎ ΡΡΠ°ΡΡΡΠ° ΠΊΠΎΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΡΠ½ΠΎΡΠ° ΠΡΠΊΡΠΈΠΊΠΈ Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ ΠΎΡΡΡΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΆΠΈΠ²Π°Π½ΠΈΡ
Introduction. Dyslipidemia and obesity are interdisciplinary and βmulti-metabolicβ diseases, pathogenetically associated with the development of atherothrombosis, which creates practical health problems. The development of both dyslipidemia and obesity is influenced by socio-demographic, environmental, genetic and many physiological and behavioral factors, while the contribution of genetic factors is 40-70%. The goal is to identify the genetic characteristics oflipid status and fat metabolism in the indigenous ethnic group of the Arctic region of the Russian Federation under conditions of permanent islandliving.Methods. A cross-sectional population study of an indigenous ethnic group (n = 44) living on Vaygach Island (70 Β° 01 ' Nlat 59 Β° 33 ' E). The reported study was funded by RFBR according to the research project β18-00-00814-(18-00-00478). Serum cholesterol and triglycerides were determined as markers oflipid metabolism in blood serum. To analyze the genetic profile, the polymorphism of the FTO A23525T gene and the LPL Ser447Ter gene was determined by polymerase chain reaction.Results. In the sample of the indigenous ethnic group, BMI was 26.0 [21.5; 29.75] kg/m2. BMI for men is 23.0 [18.0; 28.0] kg/m2, for women - 25.0 [18.0; 29.25] kg / m2. Carriers of the unfavorable allele A had a higher BMI than carriers of the T allele. Analysis of the effect of rs9939609 genetic polymorphism on thelevel of total cholesterol did not show statistically significant differences between the FTO gene genotypes. A minimal triglyceride concentration was observed in carriers of the protective genotype Ter/Ter.Conclusion. Understanding the similarities and differences in genetic susceptibility among different ethnic groups can ultimately contribute to a more focused primary prevention and patient-oriented approach of cardiovascular pathology.Β ΠΠ²Π΅Π΄Π΅Π½ΠΈΠ΅. ΠΠΈΡΠ»ΠΈΠΏΠΈΠ΄Π΅ΠΌΠΈΡ ΠΈ ΠΎΠΆΠΈΡΠ΅Π½ΠΈΠ΅ ΡΠ²Π»ΡΡΡΡΡ ΠΌΠ΅ΠΆΠ΄ΠΈΡΡΠΈΠΏΠ»ΠΈΠ½Π°ΡΠ½ΡΠΌΠΈ ΠΈ ΠΌΡΠ»ΡΡΠΈΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΡΠΎΡΡΠΎΡΠ½ΠΈΡΠΌΠΈ, ΠΏΠ°ΡΠΎΠ³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈ ΡΠ²ΡΠ·Π°Π½Ρ Ρ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ Π°ΡΠ΅ΡΠΎΡΡΠΎΠΌΠ±ΠΎΠ·Π°, ΡΠ²Π»ΡΡΡΡ Π²Π°ΠΆΠ½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠΎΠΉ ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π·Π΄ΡΠ°Π²ΠΎΠΎΡ
ΡΠ°Π½Π΅Π½ΠΈΡ. ΠΠ° ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ ΠΊΠ°ΠΊ Π΄ΠΈΡΠ»ΠΈΠΏΠΈΠ΄Π΅ΠΌΠΈΠΈ, ΡΠ°ΠΊ ΠΈ ΠΎΠΆΠΈΡΠ΅Π½ΠΈΡ Π²Π»ΠΈΡΡΡ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎ-Π΄Π΅ΠΌΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅, ΡΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅, Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈ ΠΌΠ½ΠΎΠ³ΠΈΠ΅ ΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈ ΠΏΠΎΠ²Π΅Π΄Π΅Π½ΡΠ΅ΡΠΊΠΈΠ΅ ΡΠ°ΠΊΡΠΎΡΡ, ΠΏΡΠΈ ΡΡΠΎΠΌ Π²ΠΊΠ»Π°Π΄ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΎΡΡΠ°Π²Π»ΡΠ΅Ρ 40-70%.Π¦Π΅Π»Ρ - Π²ΡΡΠ²ΠΈΡΡ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ Π»ΠΈΠΏΠΈΠ΄Π½ΠΎΠ³ΠΎ ΡΡΠ°ΡΡΡΠ° ΠΈ ΠΆΠΈΡΠΎΠ²ΠΎΠ³ΠΎ ΠΎΠ±ΠΌΠ΅Π½Π° Ρ ΠΊΠΎΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΡΠ½ΠΎΡΠ° Π°ΡΠΊΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ΅Π³ΠΈΠΎΠ½Π° Π Π€ Π² ΡΡΠ»ΠΎΠ²ΠΈΡΡ
ΠΏΠΎΡΡΠΎΡΠ½Π½ΠΎΠ³ΠΎ ΠΎΡΡΡΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΠΆΠΈΠ²Π°Π½ΠΈΡ. ΠΠ΅ΡΠΎΠ΄Ρ. ΠΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΠΏΠΎΠΏΠ΅ΡΠ΅ΡΠ½ΠΎΠ΅ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΎΠ½Π½ΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΠΊΠΎΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΡΠ½ΠΎΡΠ° (ΠΏ = 44), ΠΏΡΠΎΠΆΠΈΠ²Π°ΡΡΠ΅Π³ΠΎ Π½Π° ΠΎΡΡΡΠΎΠ²Π΅ ΠΠ°ΠΉΠ³Π°Ρ (70Β°01' Ρ. Ρ. 59Β°33' Π². Π΄.) Π² ΠΏΠ΅ΡΠΈΠΎΠ΄ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠΉ Π½Π°ΡΡΠ½ΠΎΠΉ ΡΠΊΡΠΏΠ΅Π΄ΠΈΡΠΈΠΈ, Π²ΡΠΏΠΎΠ»Π½ΡΠ΅ΠΌΠΎΠΉ Π² ΡΠ°ΠΌΠΊΠ°Ρ
ΡΠΈΠ½Π°Π½ΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π Π€Π€Π Π³ΡΠ°Π½ΡΠ° β18-00-00814-ΠΠΠΠ€Π (18-00-00478). Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΌΠ°ΡΠΊΠ΅ΡΠΎΠ² Π»ΠΈΠΏΠΈΠ΄Π½ΠΎΠ³ΠΎ ΠΎΠ±ΠΌΠ΅Π½Π° Π² ΡΡΠ²ΠΎΡΠΎΡΠΊΠ΅ ΠΊΡΠΎΠ²ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ»ΠΈ ΠΎΠ±ΡΠΈΠΉ Ρ
ΠΎΠ»Π΅ΡΡΠ΅ΡΠΈΠ½ ΠΈ ΡΡΠΈΠ³Π»ΠΈΡΠ΅ΡΠΈΠ΄Ρ. ΠΠ»Ρ Π°Π½Π°Π»ΠΈΠ·Π° Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠΎΡΠΈΠ»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»ΡΠ»ΠΈ ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌ Π³Π΅Π½Π° FTO A23525T ΠΈ Π³Π΅Π½Π° LPL Ser447Ter ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΠΏΠΎΠ»ΠΈΠΌΠ΅ΡΠ°Π·Π½ΠΎΠΉ ΡΠ΅ΠΏΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π Π²ΡΠ±ΠΎΡΠΊΠ΅ ΠΊΠΎΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΡΡΠ½ΠΎΡΠ° ΠΠΠ’ ΡΠΎΡΡΠ°Π²ΠΈΠ» 26,0 [21,5; 29,75] ΠΊΠ³/ΠΌ2. ΠΠΠ’ Π΄Π»Ρ ΠΌΡΠΆΡΠΈΠ½ - 23,0 [18,0; 28,0] ΠΊΠ³/ΠΌ2, Π΄Π»Ρ ΠΆΠ΅Π½ΡΠΈΠ½ - 25,0 [18,0; 29,25] ΠΊΠ³/ΠΌ2. ΠΠΎΡΠΈΡΠ΅Π»ΠΈ Π½Π΅Π±Π»Π°Π³ΠΎΠΏΡΠΈΡΡΠ½ΠΎΠ³ΠΎ Π°Π»Π»Π΅Π»Ρ Π ΠΈΠΌΠ΅Π»ΠΈ Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠΎΠΊΠΈΠΉ ΠΠΠ’, ΡΠ΅ΠΌ Π½ΠΎΡΠΈΡΠ΅Π»ΠΈ Π°Π»Π»Π΅Π»Ρ Π’. ΠΠ½Π°Π»ΠΈΠ· Π²Π»ΠΈΡΠ½ΠΈΡ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌΠ° rs9939609 Π½Π° ΡΡΠΎΠ²Π΅Π½Ρ ΠΎΠ±ΡΠ΅Π³ΠΎ Ρ
ΠΎΠ»Π΅ΡΡΠ΅ΡΠΈΠ½Π° Π½Π΅ ΠΏΠΎΠΊΠ°Π·Π°Π» ΡΡΠ°ΡΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈ Π·Π½Π°ΡΠΈΠΌΡΡ
ΠΎΡΠ»ΠΈΡΠΈΠΉ ΠΌΠ΅ΠΆΠ΄Ρ Π³Π΅Π½ΠΎΡΠΈΠΏΠ°ΠΌΠΈ Π³Π΅Π½Π° FTO. ΠΠΈΠ½ΠΈΠΌΠ°Π»ΡΠ½Π°Ρ ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΡ ΡΡΠΈΠ³Π»ΠΈΡΠ΅ΡΠΈΠ΄ΠΎΠ² Π±ΡΠ»Π° ΠΎΡΠΌΠ΅ΡΠ΅Π½Π° Ρ Π½ΠΎΡΠΈΡΠ΅Π»Π΅ΠΉ ΠΏΡΠΎΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π³Π΅Π½ΠΎΡΠΈΠΏΠ° Ter/Ter.ΠΠ°ΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅. ΠΠΎΠ½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΡΡ
ΠΎΠ΄ΡΡΠ²Π° ΠΈ ΡΠ°Π·Π»ΠΈΡΠΈΠΉ Π² Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π²ΠΎΡΠΏΡΠΈΠΈΠΌΡΠΈΠ²ΠΎΡΡΠΈ ΡΡΠ΅Π΄ΠΈ ΡΠ°Π·Π½ΡΡ
ΡΡΠ½ΠΎΡΠΎΠ² ΠΌΠΎΠΆΠ΅Ρ Π² ΠΊΠΎΠ½Π΅ΡΠ½ΠΎΠΌ ΠΈΡΠΎΠ³Π΅ ΡΠΏΠΎΡΠΎΠ±ΡΡΠ²ΠΎΠ²Π°ΡΡ Π±ΠΎΠ»Π΅Π΅ ΡΠ΅Π»Π΅Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½Π½ΠΎΠΉ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠΉ ΠΏΡΠΎΡΠΈΠ»Π°ΠΊΡΠΈΠΊΠ΅ ΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΎΡΠΈΠ΅Π½ΡΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΌΡ ΠΏΠΎΠ΄Ρ
ΠΎΠ΄Ρ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ
ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ Π²ΡΠ·Π²Π°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΌΠΎΠ·Π³Π° Π΄Π΅Π²ΡΡΠ΅ΠΊ-Π½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΠΈΡ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ Π³Π΅Π½ΠΎΡΠΈΠΏΠΎΠ² ΠΏΠΎ ΠΌΠ°ΡΠΊΠ΅ΡΡ MAOA -uVNTR ΠΏΡΠΈ ΠΎΡΠ΅Π½ΠΊΠ΅ ΡΠΌΠΎΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎ ΠΎΠΊΡΠ°ΡΠ΅Π½Π½ΡΡ ΡΡΠ΅Π½
Studying the correlation between the characteristics of the structure of genes and the parameters of the evoked brain activity is a relevant problem of modern research. It is known that the MAOA gene, which influences the concentration of such neurotransmitters-monoamines as dopamine, serotonin, and norepinephrine, is associated with different psychological characteristics. However, very little is known about the association of this gene with psycho-physiological indices. The purpose of the present study was to investigate the characteristics of amplitude and spatial-temporal characteristics of the evoked brain activity in girls (at the age from 18 to 24) who were carriers of different MAOA genotypes. According to the results of genotyping, the participants (61 persons) were divided into two groups: with the high-activity and heterozygous MAOA -uVNTR genotypes. In the study the authorsrecorded visual evoked potentials in 64 derivations. Emotionally charged and neutral images were stimuli in the study.The paper describes modern views on the correlation between MAOA genotypes and the features of cortico-limbic interaction. The results of the study showed that the heterozygous genotypes were apparently associated with lesser efficiency of regulating functions. To activate neural systems of the frontal divisions the female carriers of the heterozygous genotypes of MAOA needed the stimuli with a high arousal effect; this can be connected with a less efficient process of selecting relevant stimuli. At the same time, the high-activity MAOA genotypes in women are probably associated with high efficiency of controlling functions (attention, planning, control) of the prefrontal cortex when assessing emotionally charged images, which is accompanied by the intensity of activation of these brain structures.ΠΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΡΠ²ΡΠ·Π΅ΠΉ ΠΌΠ΅ΠΆΠ΄Ρ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΡΠΌΠΈ ΡΡΡΠΎΠ΅Π½ΠΈΡ Π³Π΅Π½ΠΎΠ² ΠΈ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠ°ΠΌΠΈ Π²ΡΠ·Π²Π°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΌΠΎΠ·Π³Π° β Π°ΠΊΡΡΠ°Π»ΡΠ½Π°Ρ ΡΠ΅ΠΌΠ° ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ. ΠΠ·Π²Π΅ΡΡΠ½ΠΎ, ΡΡΠΎ Π³Π΅Π½ MAOA, ΠΎΠΊΠ°Π·ΡΠ²Π°ΡΡΠΈΠΉ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π½Π° ΠΊΠΎΠ½ΡΠ΅Π½ΡΡΠ°ΡΠΈΡ ΡΠ°ΠΊΠΈΡ
Π½Π΅ΠΉΡΠΎΠΌΠ΅Π΄ΠΈΠ°ΡΠΎΡΠΎΠ²-ΠΌΠΎΠ½ΠΎΠ°ΠΌΠΈΠ½ΠΎΠ², ΠΊΠ°ΠΊ Π΄ΠΎΡΠ°ΠΌΠΈΠ½, ΡΠ΅ΡΠΎΡΠΎΠ½ΠΈΠ½ ΠΈ Π½ΠΎΡΠ°Π΄ΡΠ΅Π½Π°Π»ΠΈΠ½, Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½ Ρ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠΌΠΈ ΠΏΡΠΈΡ
ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ°ΠΌΠΈ. ΠΠ΄Π½Π°ΠΊΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°ΡΠ΅Π»ΡΡΠΊΠΈΡ
ΡΠ°Π±ΠΎΡ, ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π½ΡΡ
ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΠΈ Π΄Π°Π½Π½ΠΎΠ³ΠΎ Π³Π΅Π½Π° Ρ ΠΏΡΠΈΡ
ΠΎΡΠΈΠ·ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΡΠΌΠΈ, Π½Π° ΡΠ΅Π³ΠΎΠ΄Π½ΡΡΠ½ΠΈΠΉ Π΄Π΅Π½Ρ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎ. Π¦Π΅Π»ΡΡ Π΄Π°Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ²ΠΈΠ»ΠΎΡΡ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠ΅ΠΉ Π°ΠΌΠΏΠ»ΠΈΡΡΠ΄Π½ΡΡ
ΠΈ ΠΏΡΠΎΡΡΡΠ°Π½ΡΡΠ²Π΅Π½Π½ΠΎ-Π²ΡΠ΅ΠΌΠ΅Π½Π½ΡΡ
Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊ Π²ΡΠ·Π²Π°Π½Π½ΠΎΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΌΠΎΠ·Π³Π° Π΄Π΅Π²ΡΡΠ΅ΠΊ 18β24 Π»Π΅Ρ, ΡΠ²Π»ΡΡΡΠΈΡ
ΡΡ ΠΎΠ±Π»Π°Π΄Π°ΡΠ΅Π»ΡΠ½ΠΈΡΠ°ΠΌΠΈ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
Π³Π΅Π½ΠΎΡΠΈΠΏΠΎΠ² MAOA. ΠΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ Π³Π΅Π½ΠΎΡΠΈΠΏΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΡΠ°ΡΡΠ½ΠΈΡΡ (61 ΡΠ΅Π»ΠΎΠ²Π΅ΠΊ) Π±ΡΠ»ΠΈ ΡΠ°Π·Π΄Π΅Π»Π΅Π½Ρ Π½Π° Π΄Π²Π΅ Π³ΡΡΠΏΠΏΡ: Ρ Π²ΡΡΠΎΠΊΠΎΠ°ΠΊΡΠΈΠ²Π½ΡΠΌΠΈ ΠΈ Π³Π΅ΡΠ΅ΡΠΎΠ·ΠΈΠ³ΠΎΡΠ½ΡΠΌΠΈ Π³Π΅Π½ΠΎΡΠΈΠΏΠ°ΠΌΠΈ ΠΏΠΎ ΠΌΠ°ΡΠΊΠ΅ΡΡ MAOA -uVNTR. Π Ρ
ΠΎΠ΄Π΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π±ΡΠ»Π° ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π° ΡΠ΅Π³ΠΈΡΡΡΠ°ΡΠΈΡ Π·ΡΠΈΡΠ΅Π»ΡΠ½ΡΡ
Π²ΡΠ·Π²Π°Π½Π½ΡΡ
ΠΏΠΎΡΠ΅Π½ΡΠΈΠ°Π»ΠΎΠ² Π² 64 ΠΎΡΠ²Π΅Π΄Π΅Π½ΠΈΡΡ
. Π ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΡΡΠΈΠΌΡΠ»ΠΎΠ² Π²ΡΡΡΡΠΏΠΈΠ»ΠΈ ΡΠΌΠΎΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎ ΠΎΠΊΡΠ°ΡΠ΅Π½Π½ΡΠ΅ ΠΈ Π½Π΅ΠΉΡΡΠ°Π»ΡΠ½ΡΠ΅ ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΡ.
Π ΡΠ°Π±ΠΎΡΠ΅ ΠΎΠΏΠΈΡΠ°Π½Ρ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΈΡ ΠΎ ΡΠ²ΡΠ·ΠΈ Π³Π΅Π½ΠΎΡΠΈΠΏΠΎΠ² MAOA Ρ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΡΠΌΠΈ ΠΊΠΎΡΡΠΈΠΊΠΎ-Π»ΠΈΠΌΠ±ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ. ΠΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΠΎΠ»ΡΡΠ΅Π½ΠΎ, ΡΡΠΎ Π³Π΅ΡΠ΅ΡΠΎΠ·ΠΈΠ³ΠΎΡΠ½ΡΠ΅ Π³Π΅Π½ΠΎΡΠΈΠΏΡ, Π²Π΅ΡΠΎΡΡΠ½ΠΎ, ΡΠ²ΡΠ·Π°Π½Ρ Ρ ΠΌΠ΅Π½ΡΡΠ΅ΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ ΡΠ΅Π³ΡΠ»ΡΡΠΎΡΠ½ΡΡ
ΡΡΠ½ΠΊΡΠΈΠΉ. ΠΠ»Ρ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠΈ Π½Π΅ΠΉΡΠΎΠ½Π½ΡΡ
ΡΠΈΡΡΠ΅ΠΌ Π»ΠΎΠ±Π½ΡΡ
ΠΎΡΠ΄Π΅Π»ΠΎΠ² Π΄Π΅Π²ΡΡΠΊΠ°ΠΌ-Π½ΠΎΡΠΈΡΠ΅Π»ΡΠ½ΠΈΡΠ°ΠΌ Π³Π΅ΡΠ΅ΡΠΎΠ·ΠΈΠ³ΠΎΡΠ½ΡΡ
Π³Π΅Π½ΠΎΡΠΈΠΏΠΎΠ² MAOA Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΠ΅ ΡΠ°Π·Π΄ΡΠ°ΠΆΠΈΡΠ΅Π»Π΅ΠΉ, ΠΎΠ±Π»Π°Π΄Π°ΡΡΠΈΡ
Π²ΡΡΠΎΠΊΠΈΠΌ arousal-ΡΡΡΠ΅ΠΊΡΠΎΠΌ, ΡΡΠΎ ΠΌΠΎΠΆΠ΅Ρ Π±ΡΡΡ ΡΠ²ΡΠ·Π°Π½ΠΎ Ρ ΠΌΠ΅Π½Π΅Π΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΠΌ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠΌ ΠΎΡΠ±ΠΎΡΠ° ΡΠ΅Π»Π΅Π²Π°Π½ΡΠ½ΡΡ
ΡΡΠΈΠΌΡΠ»ΠΎΠ². Π ΡΠΎ ΠΆΠ΅ Π²ΡΠ΅ΠΌΡ, Π²ΡΡΠΎΠΊΠΎΠ°ΠΊΡΠΈΠ²Π½ΡΠ΅ Π³Π΅Π½ΠΎΡΠΈΠΏΡ MAOA Ρ ΠΆΠ΅Π½ΡΠΈΠ½, Π²Π΅ΡΠΎΡΡΠ½ΠΎ, Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Ρ Ρ Π²ΡΡΠΎΠΊΠΎΠΉ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡΡ ΡΠΏΡΠ°Π²Π»ΡΡΡΠΈΡ
ΡΡΠ½ΠΊΡΠΈΠΉ (Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅, ΠΏΠ»Π°Π½ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅, ΠΊΠΎΠ½ΡΡΠΎΠ»Ρ), Π²ΡΠΏΠΎΠ»Π½ΡΠ΅ΠΌΡΡ
ΠΏΡΠ΅ΡΡΠΎΠ½ΡΠ°Π»ΡΠ½ΡΠΌΠΈ ΠΎΡΠ΄Π΅Π»Π°ΠΌΠΈ ΠΊΠΎΡΡ ΠΌΠΎΠ·Π³Π° ΠΏΡΠΈ ΠΎΡΠ΅Π½ΠΊΠ΅ ΡΠΌΠΎΡΠΈΠΎΠ½Π°Π»ΡΠ½ΠΎ ΠΎΠΊΡΠ°ΡΠ΅Π½Π½ΡΡ
ΠΈΠ·ΠΎΠ±ΡΠ°ΠΆΠ΅Π½ΠΈΠΉ, ΡΡΠΎ ΡΠΎΠΏΡΠΎΠ²ΠΎΠΆΠ΄Π°Π΅ΡΡΡ Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΠΉ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΡΡΡΡ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΠΈ Π΄Π°Π½Π½ΡΡ
ΠΌΠΎΠ·Π³ΠΎΠ²ΡΡ
ΡΡΡΡΠΊΡΡΡ
Formation of synergetic effect of human resource management of business organization
The article presents the contents of synergetic effect of human resources management of business organization which can be seen in excess of the sum of results of work of all employees as human capital bearers above the results of work of individual employees with unique professional competencies together with knowledge, abilities and experience as the sources of competitive strengths of business organization. Predictions of development of business organization taking into account the influence of possibility of formation of synergetic effect on different stages of human resources life cycle are presented
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