672 research outputs found

    A Provisional List of the Species of Septoria in Iowa

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    There are over 1,200 species of the genus Septoria, all of them being parasitic. Most of the members of the genus occur on wild hosts, but several of them cause diseases of great importance on cultivated plants

    Formulation and evaluation of transdermal delivery system of an anti-hypertensive drug

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    oai:ojs2.japtronline.com:article/1The present study was aims to formulate and evaluate transdermal drug delivery for sustained release of an anti-hypertensive drug Captopril, it is considered as drug of choice in anti hypertensive therapy and is reported for potential administration through transdermal route. The investigation was carried out to study the effect of different proportion of ethyl cellulose and PVP a hydrophobic and hydrophilic polymer respectively. Transdermal patches were prepared using different combination of the two polymers by solvent evaporation technique. Polyvinyl alcohol was used to prepare the backing membrane and dibutyl phthalate as a plasticizer. Several Physicochemical parameter like moisture content, moisture loss, thickness, film folding endurance, tensile strength, flatness were studied. For all the formulations, in vitro drug release was studied using modified diffusion cell. Formulations with highest proportion of polyvinyl pyrolidone shows faster release whereas increasing proportion of ethyl cellulose produces a prolonged regimen of sustained drug delivery through transdermal route for a period of 24 hrs

    An electrically driven solid state modulator

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    Simulation results for the design and fabrication of an electrically driven solid state modulator are presented. The design criteria has identified various trade-offs in the manufacturing of an electrically driven modulator using a p-i-n diode to be made from high purity Ge. The issues relating to the doping, layer thickness and contact material for the diode fabrication are discussed. A compromise between the high 'ON' state transmission and uniformity is required to achieve the optimum performance from the device. Using FEMLAB and ATLAS a p-i-n diode with different apertures has been simulated which clearly show the effects of non-uniformity and the requirement of a mesh-type electrode for a uniform absorption across the large device apertures

    Community-engaged primary care medical education

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    BACKGROUND: Community-engaged medical education (CEME) requires medical schools to partner with local communities to help address community priorities, whilst enhancing the learning experiences of students. Current literature on CEME has focused on evaluating its effects on students; however, there remains a gap in exploring whether CEME initiatives can have a sustainable impact for communities. APPROACH: The Community Action Project (CAP) at Imperial College London, is an eight-week, community-engaged, quality improvement project for Year 3 medical students. Students initially consult with clinicians, patients and wider community stakeholders to understand local needs and assets, and identify a health priority to address. They then work with relevant stakeholders to design, implement and evaluate a project to help address their identified priority. EVALUATION: All CAPs (n = 264) completed in the 2019-2021 academic years were evaluated for evidence of several key areas, including community engagement and sustainability. 91% of projects evidenced a needs analysis, 71% demonstrated patient involvement in their development, and 64% demonstrated sustainable impacts from their projects. Analysis revealed the topics frequently addressed, and the formats used by students. Two CAPs are described in more detail to demonstrate their community impact. IMPLICATIONS: The CAP demonstrates how the principles of CEME (meaningful community engagement and social accountability) can lead to sustainable benefits for local communities through purposeful collaboration with patients and local communities. Strengths, limitations and future directions are highlighted

    Nonfactorization in Hadronic Two-body Cabibbo-favored decays of D^0 and D^+

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    With the inclusion of nonfactorized amplitudes in a scheme with Nc=3N_c=3, we have studied Cabibbo-favored decays of D0D^0 and D+D^+ into two-body hadronic states involving two isospins in the final state. We have shown that it is possible to understand the measured branching ratios and determined the sizes and signs of nonfactorized amplitudes required.Comment: 15 pages, Late
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