Performance of cotton genotype TCH 1819 to high density planting system under winter irrigated condition at the Western agroclimatic zone of Tamil Nadu

Plant population is an important attribute in crop management practice. Increasing the plant density by decreasing the crop row spacing was an alternative strategy to optimize crop profit. Hence, the field trial was conducted at Tamil Nadu Agricultural University, Coimbatore, during the winter season of 2017 – 18 to study the effect of row spacing on the growth and yield of cotton genotype TCH 1819. The experimental design was Randomized Block Design (RBD) with seven spacing treatments viz., T1: 60 x 15 cm (1,11,111 plants ha-1), T2: 60 x 20 cm (83,333 plants ha-1), T3: 75 x 15 cm (88,888 plants ha-1), T4: 75 x 20 cm (66,666 plants ha-1), T5: 75 x 30 cm (44,444 plants ha-1), T6: 90 x 15 cm (74074 plants ha-1), T7: 90 x 20cm (55,555 plants ha-1) and was replicated thrice.  Plant densities showed a significant (p=0.05) difference for all the characters studied.  The higher plant density of 1,11,111 plants (60 x 15 cm) observed significantly (p=0.05) maximum plant height (103.14 cm), Leaf Area Index (LAI) (4.35), Dry Matter Production (DMP) (8125 kg/ha), Crop Growth Rate (CGR) (6.58 g/m2/day), root length (41.46 cm), root dry weight (14.94 g/plant), and chlorophyll index (48.24).  The number of sympodial branches per plant (17) and bolls per plant (22 bolls) was found significant in the wider spacing of 75 x 30 cm.  The narrow spacing of 60 x 15 cm noted the highest seed cotton yield (2565 kg/ha), net return (R65706.62), and B: C (2.32) ratio, followed by the spacing of 75 x 15 cm due to more plant density per unit area (m2).  So, maximum yield in cotton can be achieved by decreasing the row spacing and increasing the plant population per unit area

Complication of Salmonella Bacteremia in a Case of Treated Fungal Endophthalmitis

This is to report a case of bacteremia caused by Salmonella typhi in a treated unilateral fungal endogenous endophthalmitis in an 18-year-old male from one of the South Asian countries. Microbiological and molecular investigations were carried out on the eviscerated material and routine blood culture was carried out. Direct examination of eviscerated material revealed the presence of fungal filaments. However, Salmonella typhi was isolated from both specimens, which was confirmed by Polymerase chain reaction targeting the 16SrRNA gene, sequencing, and random amplification of polymorphic DNA showed that they belonged to the same clone. The presence of Salmonella bacteremia in a treated unilateral fungal endophthalmitis, among young adult patients is rare and systemic symptoms should be investigated

Device Closure of Superior Sinus Venosus Atrial Septal Defects: A single centre experience

Sinus venosus atrial septal defects present a wide variety of anatomical features and are frequently associated with partial anomalous pulmonary venous drainage of one or more right pulmonary veins. Surgical correction used to be the standard treatment. In recent times, transcatheter correction of superior sinus venosus atrial septal defects has come into vogue. The transcatheter closure of these defects with covered stents at a tertiary care centre in Oman between 2018 and 2023 is reported. Keywords: Heart Septal Defects, Atrial; Vena Cava, Superior; Endovascular Procedures; Stents; Cardiac Catheterization; Echocardiography, Transesophageal; Oman

BSSB: BLAST Server for Structural Biologists

The Basic Local Alignment Search Tool (BLAST) is one of the most widely used sequence alignment programs with which similarity searches, for both protein and nucleic acid sequences, can be performed against large databases at high speed. A large number of tools exist for processing BLAST output, but none of them provide three-dimensional structure visualization. This shortcoming has been addressed in the proposed tool BLAST Server for Structural Biologists (BSSB), which maps a BLAST output onto the three-dimensional structure of the subject protein. The three-dimensional structure of the subject protein is represented using a three-color coding scheme (identical: red; similar: yellow; and mismatch: white) based on the pairwise alignment obtained. Thus, the user will be able to visualize a possible three-dimensional structure for the query protein sequence. This information can be used to gain a deeper insight into the sequence-structure correlation. Furthermore, the additional structure-level information enables the user to make coherent and logical decisions regarding the type of input model structure or fragment that can be used for molecular replacement calculations. This tool is freely available to all users at http://bioserver1.physics.iisc.ernet.in/bssb/

Study of risk factors in myopic individuals among medical students in Chennai, Tamil Nadu

Background: The incidence of myopia is increasing at an alarming rate. Investigating the causes of myopia gives us a better understanding of it. This gives us better odds of preventing the occurrence and retarding the condition's progression. The study used a method called stratified sampling to select 100 individuals who were near-sighted. They belonged to the age of 17-30 years old and pursued medicine in the district of Kanchipuram. The role of risk factors was assessed through a questionnaire. Result: The percentage of subjects with low, medium, and high myopia was 77, 18, and 5, respectively. The role of heredity, diet, academic performance, time spent doing near work, and outdoor work was indeed found to play significant roles in the development and progression of myopia. Conclusion: The incidence of myopia is constantly increasing, especially in Asian countries. To prevent myopia and its complications, we need to take significant steps to reduce the risk factors that can be changed

Synthesis of-4-((4-trimethylsilyl-1<i>H</i>-1,2,3-triazol-1-yl)methyl)-2<i>H</i>-chromen-2-ones: A novel class of heteroaryl anionic synthon

<p>A one-pot synthesis of some novel anionic scaffolds: the substituted-4-((4-trimethylsilyl-1<i>H</i>-1,2,3-triazol-1-yl)methyl)-2<i>H</i>-chromen-2-one is reported. Reaction of 10 different substituted bromomethylcoumarins with trimethylsilylacetylene and sodium azide in the presence of copper(I) iodide catalyst gave the corresponding heteroaryl conjugates: the substituted-4-((4-trimethylsilyl-1<i>H</i>-1,2,3-triazol-1-yl)methyl)-2<i>H</i>-chromen-2-one in 70–92% yields. The structures of the synthesized compounds have been completely characterized by spectral and elemental analyses. For the first time, the representative single-crystal X-ray structure analysis of 6-methoxy-4-((4-trimethylsilyl-1<i>H</i>-1,2,3-triazol-1-yl)methyl)-2<i>H</i>-chromen-2-one is reported which confirms the formation of anionic synthon which bears the trimethylsilyl-group.</p

Synthesis of-4-((4-trimethylsilyl-1<i>H</i>-1,2,3-triazol-1-yl)methyl)-2<i>H</i>-chromen-2-ones: A novel class of heteroaryl anionic synthon

<p>A one-pot synthesis of some novel anionic scaffolds: the substituted-4-((4-trimethylsilyl-1<i>H</i>-1,2,3-triazol-1-yl)methyl)-2<i>H</i>-chromen-2-one is reported. Reaction of 10 different substituted bromomethylcoumarins with trimethylsilylacetylene and sodium azide in the presence of copper(I) iodide catalyst gave the corresponding heteroaryl conjugates: the substituted-4-((4-trimethylsilyl-1<i>H</i>-1,2,3-triazol-1-yl)methyl)-2<i>H</i>-chromen-2-one in 70–92% yields. The structures of the synthesized compounds have been completely characterized by spectral and elemental analyses. For the first time, the representative single-crystal X-ray structure analysis of 6-methoxy-4-((4-trimethylsilyl-1<i>H</i>-1,2,3-triazol-1-yl)methyl)-2<i>H</i>-chromen-2-one is reported which confirms the formation of anionic synthon which bears the trimethylsilyl-group.</p