Transverse instability of the antiproton beam in the Recycler Ring

The brightness of the antiproton beam in Fermilab's 8 GeV Recycler ring is limited by a transverse instability. This instability has occurred during the extraction process to the Tevatron for large stacks of antiprotons even with dampers in operation. This paper describes observed features of the instability, introduces the threshold phase density to characterize the beam stability, and finds the results to be in agreement with a resistive wall instability model. Effective exclusion of the longitudinal tails from Landau damping by decreasing the depth of the RF potential well is observed to lower the threshold density by up to a factor of two.Comment: 3 pp. Particle Accelerator, 24th Conference (PAC'11) 2011. 28 Mar - 1 Apr 2011. New York, US

Influence d'une alimentation séquentielle sur l'épuration par boues activées d'un effluent fortement chargé

Cet article présente les résultats d'une étude menée sur le traitement d'effluents fortement chargés (DCO > 1,5 kg.m-3) par un procédé à boues activées. L'objectif principal de ce travail est de montrer qu'une alimentation séquentielle d'un réacteur parfaitement agité avec maintien permanent du recyclage des boues et de l'oxygénation permet d'obtenir une bonne épuration tant du point de vue de l'élimination de la pollution carbonée que de la maîtrise de la décantabilité des flocs microbiens. Les essais sont menés sur un pilote de laboratoire constitué d'une colonne à bulles et d'un décanteur, alimenté avec un substrat synthétique. Contrairement à une alimentation continue, la mise en place de cycles d'alimentation permet d'obtenir des flocs de bonne décantabilité de manière constante dans le temps. Ainsi une concentration élevée en biomasse peut être maintenue dans le réacteur. De plus, le suivi d'un cycle 1 h/1 h confirme que la mise en œuvre d'un cycle court n'entraîne pas de variations importantes des performances d'épuration. Par ailleurs, le suivi d'un long cycle (24 h/24 h) montre des variations significatives des concentrations en DCO, polysaccharides dans la phase liquide et exopolysaccharides dans les flocs microbiens. Ceci semble indiquer que des produits microbiens sont relargués des flocs vers la phase liquide pendant l'arrêt de l'alimentation et que des exopolysaccharides sont produits dans les flocs pendant l'alimentation.The overall efficiency of an activated sludge wastewater treatment system depends both on the ability of the activated sludge culture to remove the soluble organic pollution and on the efficiency of the separation of the treated water from the biomass. In the treatment of a high-strength wastewater (COD > 1.5 kg .m-3), ultrafiltration or crossflow filtration systems can sometimes substitute for the final clarifier, the separation of the sludge from the effluent water being very good regardless of changes in sludge settleability. Because of the high pollutant concentrations, the biomass must be more concentrated in the bioreactor than in the usual aerobic processes (10 to 20 kg.m-3 rather than 4 kg.m-3), whatever the separation system (settler or filtration system). Thus, with this biomass concentration, the volumetric loading rate can be increased while the organic loading rate is maintained at a low level.The use of a clarifier is preferable because it is cheaper than ultrafiltration or crossflow filtration systems, which have very high investment and operation costs, on the other hand, and some fouling problems, on the other hand. However, its use requires a very good biomass settleability. Results from the literature show that there is no general relation between sludge settleability and such wastewater treatment operating parameters as dissolved oxygen concentration in the aeration basin, organic loading rates, pH, or low relative influent nitrogen and phosphorus contents. On the other hand, the separation ability of the clarifier depends on the hydraulic configuration of the aerated reactor: biomass settleability can be controlled by completely stirred reactors in series, plug-flow reactors or intermittently-fed systems. Indeed, this spatial or temporal staggering should allow microorganisms to consume their accumulated substrate and thus restore their accumulation capacity. In the case of high-strength wastewater treatment, temporal staggering is better than spatial staggering. Indeed, higher organic loading rates require a higher number of reactors. Thus, the COD concentration significantly increases in the first reactors of the cascade and some toxic or inhibitory problems could appear. For this reason, a temporal staggering was chosen.Biomass settleability is linked to the extracellular polymers that are the third component of the sludge flocs, after the cells and the water. These polymers are composed largely of microbial exopolysaccharides. Measurements of exopolysaccharides could be used to characterize sludge settleability. A too low level of exopolysaccharides indicates a sludge defloculation problem, whereas a too high level of exopolysaccharides means that sludge settleability could be hindered because of an excessive growth of filamentous organisms.The purpose of the present work is to show that the use of only one completely stirred reactor, fed in a cyclic way with permanent oxygenation and return sludge flow, leads to good sludge settleability and effluent quality. The experiments have been performed with a laboratory pilot-plant composed of a 11.3 litre bubble column, which is a completely stirred reactor, and a secondary settling tank of 14.8 litres. The reactor is fed with an equilibrated synthetic substrate consisting mainly of meat extract, saccharose and ethanol (COD:N:P=100:5:1 and 1 kg COD=1 kg meat extract + 0.444 kg saccharose + 0.2 kg ethanol). The feeding cycle is a set of consecutive periods of feeding and starvation. For example, during a 1h/2h feeding cycle, the substrate feeding is continuous during 1 hour and stopped during 2 hours.The sludge comes from the Nancy-Maxéville wastewater treatment plant and its acclimation to the synthetic substrate begins with an aeration without feeding during 12 hours. Afterwards, the experimental system is fed during 1 hour every 2 hours with the substrate (first concentration of COD=0.1 kg.m-3). Then, the inlet COD is increased by steps of 0.1 kg.m-3 every day until the required concentration is reached. Once the biomass is acclimated to the influent and sufficiently concentrated, the experiment can begin.In order to show the positive influence of cyclic feeding on wastewater treatment quality, we have carried out one experiment with continuous feeding and two experiments with cyclic feeding (see Table 1). For these experiments, the volumetric loading rate is about 4 kg COD.m-3.d-1. With an appropriate feeding cycle, the settleability of the sludge and the effluent quality remain good: the diluted sludge volume index is 56 cm3.g-1 and 96% of the inlet COD is removed. Thus, the biomass concentration remains high in the reactor (19 kg.m-3). This is not the case with a continuous feeding where the biomass settleability rapidly deteriorates. The principal advantage of sequential feeding is the maintenance of good sludge settleability and a high biomass concentration in the aeration basin. Moreover, during the short feeding cycles, the variations of the concentrations of COD, polysaccharides in the bulk phase and extracellular polysaccharides in the microbial aggregates are very low. This augurs well for system stability.In contrast, monitoring of a long cycle (24 h of feeding and 24 h of starvation) shows great variations in the concentrations of COD, polysaccharides and extracellular polysaccharides in the system. When the feeding is stopped, the COD and polysaccharide concentrations in the bulk phase increase whereas the exopolysaccharide concentration in sludge flocs decreases. Reciprocally, after the feeding is begun, the COD and polysaccharide concentrations in the bulk phase decrease, and then remain constant, whereas the exopolysaccharide concentration increases. As 1 kg of measured polysaccharides represents 0.9 kg COD, and as in the bulk phase the COD concentration is equivalent to 4 times the polysaccharide concentration, it seems that microbial products other than polysaccharides are released in the bulk phase during starvation, these products being slowly biodegradable. Extracellular polysaccharides in the microbial aggregates are formed during the feeding phase

Escape configuration lattice near the nematic-isotropic transition: Tilt analogue of blue phases

We predict the possible existence of a new phase of liquid crystals near the nematic-isotropic ($NI$) transition. This phase is an achiral, tilt-analogue of the blue phase and is composed of a lattice of {\em double-tilt}, escape-configuration cylinders. We discuss the structure and the stability of this phase and provide an estimate of the lattice parameter.Comment: 5 pages, 6 figures (major revision, typos corrected, references added

Classical orbital paramagnetism in non-equilibrium steady state

We report the results of our numerical simulation of classical-dissipative dynamics of a charged particle subjected to a non-markovian stochastic forcing. We find that the system develops a steady-state orbital magnetic moment in the presence of a static magnetic field. Very significantly, the sign of the orbital magnetic moment turns out to be {\it paramagnetic} for our choice of parameters, varied over a wide range. This is shown specifically for the case of classical dynamics driven by a Kubo-Anderson type non-markovian noise. Natural spatial boundary condition was imposed through (1) a soft (harmonic) confining potential, and (2) a hard potential, approximating a reflecting wall. There was no noticeable qualitative difference. What appears to be crucial to the orbital magnetic effect noticed here is the non-markovian property of the driving noise chosen. Experimental realization of this effect on the laboratory scale, and its possible implications are briefly discussed. We would like to emphasize that the above steady-state classical orbital paramagnetic moment complements, rather than contradicts the Bohr-van Leeuwen (BvL) theorem on the absence of classical orbital diamagnetism in thermodynamic equilibrium.Comment: 6 pages, 4 figures, Has appeared in Journal of Astrophysics and Astronomy special issue on 'Physics of Neutron Stars and Related Objects', celebrating the 75th birth-year of G. Srinivasa

Polarity patterns of stress fibers

Stress fibers are contractile actomyosin bundles commonly observed in the cytoskeleton of metazoan cells. The spatial profile of the polarity of actin filaments inside contractile actomyosin bundles is either monotonic (graded) or periodic (alternating). In the framework of linear irreversible thermodynamics, we write the constitutive equations for a polar, active, elastic one-dimensional medium. An analysis of the resulting equations for the dynamics of polarity shows that the transition from graded to alternating polarity patterns is a nonequilibrium Lifshitz point. Active contractility is a necessary condition for the emergence of sarcomeric, alternating polarity patterns.Comment: 5 pages, 3 figure

Handwashing, sanitation and family planning practices are the strongest underlying determinants of child stunting in rural indigenous communities of Jharkhand and Odisha, Eastern India: a cross-sectional study

The World Health Organisation has called for global action to reduce child stunting by 40% by 2025. One third of the world's stunted children live in India, and children belonging to rural indigenous communities are the worst affected. We sought to identify the strongest determinants of stunting among indigenous children in rural Jharkhand and Odisha, India, to highlight key areas for intervention. We analysed data from 1227 children aged 6–23.99 months and their mothers, collected in 2010 from 18 clusters of villages with a high proportion of people from indigenous groups in three districts. We measured height and weight of mothers and children, and captured data on various basic, underlying and immediate determinants of undernutrition. We used Generalised Estimating Equations to identify individual determinants associated with children's height-for-age z-score (HAZ; p < 0.10); we included these in a multivariable model to identify the strongest HAZ determinants using backwards stepwise methods. In the adjusted model, the strongest protective factors for linear growth included cooking outdoors rather than indoors (HAZ +0.66), birth spacing ≥24 months (HAZ +0.40), and handwashing with a cleansing agent (HAZ +0.32). The strongest risk factors were later birth order (HAZ −0.38) and repeated diarrhoeal infection (HAZ −0.23). Our results suggest multiple risk factors for linear growth faltering in indigenous communities in Jharkhand and Odisha. Interventions that could improve children's growth include reducing exposure to indoor air pollution, increasing access to family planning, reducing diarrhoeal infections, improving handwashing practices, increasing access to income and strengthening health and sanitation infrastructure

Sexually dimorphic role for vasopressin in the development of social play

Despite the well-established role of vasopressin (AVP) in adult social behavior, its role in social development is relatively unexplored. In this paper, we focus on the most prominent social behavior of juvenile rats, social play. Previous pharmacological experiments in our laboratory suggested that AVP regulates play in a sex- and brain region-specific manner in juvenile rats. Here we investigate the role of specific AVP systems in the emergence of social play. We first characterize the development of play in male and female Wistar rats and then ask whether the development of AVP mRNA expression correlates with the emergence of play. Unexpectedly, play emerged more rapidly in weanling-aged females than in males, resulting in a sex difference opposite of that typically reported for older, juvenile rats. AVP mRNA and play were correlated in males only, with a negative correlation in the bed nucleus of the stria terminalis and a positive correlation in the paraventricular nucleus of the hypothalamus. These findings support the hypothesis that AVP acts differentially on multiple systems in a sex-specific manner to regulate social play and suggest a role for PVN and BNST AVP systems in the development of play. Differential neuropeptide regulation of male and female social development may underlie well-documented sex differences in incidence, progression, and symptom severity of behavioral disorders during development

Economic evaluation of participatory learning and action with women's groups facilitated by Accredited Social Health Activists to improve birth outcomes in rural eastern India

BACKGROUND: Neonatal mortality remains unacceptably high in many low and middle-income countries, including India. A community mobilisation intervention using participatory learning and action with women’s groups facilitated by Accredited Social Health Activists (ASHAs) was conducted to improve maternal and newborn health. The intervention was evaluated through a cluster-randomised controlled trial conducted in Jharkhand and Odisha, eastern India. This aims to assess the cost-effectiveness this intervention. METHODS: Costs were estimated from the provider’s perspective and calculated separately for the women’s group intervention and for activities to strengthen Village Health Sanitation and Nutrition Committees (VHNSC) conducted in all trial areas. Costs were estimated at 2017 prices and converted to US dollar (USD). The incremental cost-effectiveness ratio (ICER) was calculated with respect to a do-nothing alternative and compared with the WHO thresholds for cost-effective interventions. ICERs were calculated for cases of neonatal mortality and disability-adjusted life years (DALYs) averted. RESULTS: The incremental cost of the intervention was USD 83 per averted DALY (USD 99 inclusive of VHSNC strengthening costs), and the incremental cost per newborn death averted was USD 2545 (USD 3046 inclusive of VHSNC strengthening costs). The intervention was highly cost-effective according to WHO threshold, as the cost per life year saved or DALY averted was less than India’s Gross Domestic Product (GDP) per capita. The robustness of the findings to assumptions was tested using a series of one-way sensitivity analyses. The sensitivity analysis does not change the conclusion that the intervention is highly cost-effective. CONCLUSION: Participatory learning and action with women’s groups facilitated by ASHAs was highly cost-effective to reduce neonatal mortality in rural settings with low literacy levels and high neonatal mortality rates. This approach could effectively complement facility-based care in India and can be scaled up in comparable high mortality settings

Transverse Instabilities in the Fermilab Recycler

Transverse instabilities of the antiproton beam have been observed in the Recycler ring soon after its commissioning. After installation of transverse dampers, the threshold for the instability limit increased significantly but the instability is still found to limit the brightness of the antiprotons extracted from the Recycler for Tevatron shots. In this paper, we describe observations of the instabilities during the extraction process as well as during dedicated studies. The measured instability threshold phase density agrees with the prediction of the rigid beam model within a factor of 2. Also, we conclude that the instability threshold can be significantly lowered for a bunch contained in a narrow and shallow potential well due to effective exclusion of the longitudinal tails from Landau damping.Comment: 17 pages, 'Technical' Note, Use of 'internal' jargon and reference

Participatory women’s groups and counseling through home visits to improve child growth in rural eastern India: protocol for a cluster randomised controlled trial

Background: Childhood stunting (low height-for-age) is a marker of chronic undernutrition and predicts children’s subsequent physical and cognitive development. An estimated 52 million children in India are stunted. There is a broad consensus on determinants of child undernutrition and interventions to address it, but a lack of operational research testing strategies to increase the coverage of these interventions in high burden areas. Our study aims to assess the impact, costeffectiveness, and scalability of a community intervention involving a government-proposed community-based worker to improve growth in children under two