Prevalence of menstrual morbidity in adolescents girls: a cross sectional study

Background: Menstruation is said to be a physiological process in women. The word ‘menstruation’ was derived from a Latin word ‘menses’. Menstrual dysfunction was found to affect 75% of adolescent girls which includes dysmenorrhoea, menorrhagia and irregular cycles. Premenstrual syndrome constitutes a group of physical and emotional symptoms which occurs one week before menstrual cycle. It was found to be a cycle disorder which appears in the luteal phase. Adolescent girls are at high risk of developing premenstrual syndrome. Because of menstrual dysfunction and premenstrual syndrome, the adolescent girls are at high risk of menstrual morbidity.Methods: After getting approval from institutional ethical committee of Madras Medical College, the study was carried out in adolescent girls. The study was carried out by giving questionnaire in nearly 505 students for the duration of 6 months. The study participants were explained about the study. The questionnaire was structured so as to obtain information regarding the age at menarche, duration of cycle, awareness about menstruation, source of information regarding menstruation, practices during menstrual cycles, regarding menstrual problems and treatment practices.Results: The average age of participants was 17 years with an SD of 1.5. of 505 participants, about 6% had 45 days frequency, 10% had 38 days frequency and 2% had 60 days frequency of menstrual cycle. It was found around 1% had 8 days duration and 3% had 9 days duration of menstrual cycle. About 13% of Participants had mild flow, 7% had severe flow and 20% had variable quantity of menstrual flow.Conclusions: From this study, it was found that menstrual dysfunction were prevalent among adolescent girls. These were found to cause menstrual morbidity among adolescent girls. Hence it is necessary to educate and create awareness about menstrual morbidity among adolescent girls.

ISOLATION AND CHARACTERIZATION OF CHITIN FROM PRAWN SHELL WASTE AND INCORPORATION INTO MEDICAL TEXTILES

ABSTRACT Chitin is one of the most abundant natural polysaccharide on earth. Different crustaceans, molluses, marine diatoms, insects, algae, fungi and yeast synthesize it. According to the amount of chitin produced annually over the world, it is second abundant polymer next to cellulose. Recent investigations confirm the suitability of chitin and its derivatives in chemistry, biotechnology, medicine, and food processing, environmental protection and also used as a safe excipient in drug delivery formulations. Our present study focused that on the isolate the prawn shell waste and conversion to chitosan.Chitosan was characterized using IR spectrum and compared with standard to confirm the presence of chitosan in the shell of prawn. We attempted to incorporate latex milk of Euphorbia neriifolia, which has potent medicinal properties with chitosan and check its antimicrobial activity. The results of the present study proved the antimicrobial activity exhibited by the samples incorporated in medical textiles on test organisms

Special Issue 01

ABSTRACT 1.INTRODUCTION Wireless mesh networks (WMNs) are being developed actively and deployed widely for a variety of applications, such as public safety, environment monitoring, and citywide wireless Internet services. The wireless backbone, consisting of wireless mesh routers equipped with one or more radio interfaces, highly affects the capacity of the mesh network. This has a significant impact on the overall performance of the system, thus generating extensive research in order to tackle the specific challenges of the WMN. This configuration adversely affects the capacity of the mesh due to interference from adjacent nodes in the network. Directional antennas and modified MAC protocols make the practical deployment of such solutions infeasible on a wide scale, the main issue in using multiple channels with a single radio is that dynamic channel switching requires tight time synchronization between the nodes. The protocol makes use of the knowledge of network topology by utilizing selective flooding of control messages in a portion of the network. In this way, broadcasting of control messages is avoided and thus the chances of network congestion and disruption of the flows in the network are reduced. A typical WMN application consists of three levels: wired networks, the WMN backbone, and mesh clients. Wired networks contain most resources in WMNs, such as file servers, file transfer protocol servers, etc. The WMN backbone is a collection of static wireless mesh routers. Traffic loads between the wired network and mobile users in mesh clients are transmitted by the WMN backbone in a multihop manner. Mesh clients can connect to the WMN backbone by establishing either wired or wireless links with mesh routers. WMN architecture as shown i

Pharmacoinformatic investigation of medicinal plants from East Africa

Medicinal plants have widely been used in the traditional treatment of ailments and have been proven effective. Their contribution still holds an important place in modern drug discovery due to their chemical, and biological diversities. However, the poor documentation of traditional medicine, in developing African countries for instance, can lead to the loss of knowledge related to such practices. In this study, we present the Eastern Africa Natural Products Database (EANPDB) containing the structural and bioactivity information of 1870 unique molecules isolated from about 300 source species from the Eastern African region. This represents the largest collection of natural products (NPs) from this geographical region, covering literature data of the period from 1962 to 2019. The computed physicochemical properties and toxicity profiles of each compound have been included. A comparative analysis of some physico-chemical properties like molecular weight, H-bond donor/acceptor, logP(o/w), etc. as well scaffold diversity analysis has been carried out with other published NP databases. EANPDB was combined with the previously published Northern African Natural Products Database (NANPDB), to form a merger African Natural Products Database (ANPDB), containing similar to 6500 unique molecules isolated from about 1000 source species (freely available at http://african-compounds.org). As a case study, latrunculins A and B isolated from the spongeNegombata magnifica(Podospongiidae) with previously reported antitumour activities, were identified via substructure searching as molecules to be explored as putative binders of histone deacetylases (HDACs)

The Green, Green Grass of Home: an archaeo-ecological approach to pastoralist settlement in central Kenya

© 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. This paper considers the ecological residues of pastoralist occupation at the site of Maili Sita in Laikipia, central Kenya, drawing links with the archaeological record so as to contribute a fresh approach to the ephemeral settlement sites of mobile herding communities, a methodological aspect of African archaeology that remains problematic. Variations in the geochemical and micromorphological composition of soils along transects across the site are compared with vegetation distributions and satellite imagery to propose an occupation pattern not dissimilar to contemporary Cushitic-speaking groups further north. We argue that Maili Sita exemplifies the broad migratory and cultural exchange networks in place during the mid- to late second millennium AD, with pastoralist occupants who were both physically and culturally mobile.British Academy (2002-5 Funding) European Union - Marie Curie Initiatives (EXT grant 2007-11

First measurement of the nuclear-recoil ionization yield in silicon at 100 eV

We measured the nuclear--recoil ionization yield in silicon with a cryogenic phonon-sensitive gram-scale detector. Neutrons from a mono-energetic beam scatter off of the silicon nuclei at angles corresponding to energy depositions from 4\,keV down to 100\,eV, the lowest energy probed so far. The results show no sign of an ionization production threshold above 100\,eV. These results call for further investigation of the ionization yield theory and a comprehensive determination of the detector response function at energies below the keV scale

Search for low-mass dark matter via bremsstrahlung radiation and the Migdal effect in SuperCDMS

We present a new analysis of previously published SuperCDMS data using a profile likelihood framework to search for sub-GeV dark matter (DM) particles through two inelastic scattering channels: bremsstrahlung radiation and the Migdal effect. By considering these possible inelastic scattering channels, experimental sensitivity can be extended to DM masses that are undetectable through the DM-nucleon elastic scattering channel, given the energy threshold of current experiments. We exclude DM masses down to 220  MeV/c2 at 2.7×10−30  cm2 via the bremsstrahlung channel. The Migdal channel search provides overall considerably more stringent limits and excludes DM masses down to 30  MeV/c2 at 5.0×10−30  cm2

A Search for Low-mass Dark Matter via Bremsstrahlung Radiation and the Migdal Effect in SuperCDMS

We present a new analysis of previously published of SuperCDMS data using a profile likelihood framework to search for sub-GeV dark matter (DM) particles through two inelastic scattering channels: bremsstrahlung radiation and the Migdal effect. By considering these possible inelastic scattering channels, experimental sensitivity can be extended to DM masses that are undetectable through the DM-nucleon elastic scattering channel, given the energy threshold of current experiments. We exclude DM masses down to $220~\textrm{MeV}/c^2$ at $2.7 \times 10^{-30}~\textrm{cm}^2$ via the bremsstrahlung channel. The Migdal channel search provides overall considerably more stringent limits and excludes DM masses down to $30~\textrm{MeV}/c^2$ at $5.0 \times 10^{-30}~\textrm{cm}^2$.Comment: Submitted to PR