31 research outputs found

    Pengaruh Citra Merek Dan Gaya Hidup Terhadap Keputusan Pembelian Oppo Smartphone (Studi Kasus FEB UNISMA 2017)

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    Abstract This study examines the effect of brand image and lifestyle on OPPO Smartphone purchasing decisions on FEB Unisma 2017 students. The type used is Explanatory Research with a quantitative approach to 90 respondents. This study uses multiple linear regression analysis techniques.  The results of the study show that brand image has an effect on OPPO Smartphone Purchase Decisions for Students of the Faculty of Business Economics, Islamic University of Malang in the 2017 batch. Second, Lifestyle has an effect on OPPO Smartphone Purchase Decisions for Students of the Faculty of Business Economics, Islamic University of Malang in the 2017 batch. And thirdly, the influence of brand image and lifestyle together has a simultaneous effect on purchasing decisions. Keywords : Purchase Decisions, Brand Image And Lifestyle.

    Control of Propionibacterium acnes by natural antimicrobial substances: Role of the bacteriocin AS-48 and lysozyme

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    We report the high susceptibility of several clinical isolates of Propionibacterium acnes from different sources (skin, bone, wound exudates, abscess or blood contamination) to the head-to-tail cyclized bacteriocin AS-48. This peptide is a feasible candidate for further pharmacological development against this bacterium, due to its physicochemical and biological characteristics, even when it is growing in a biofilm. Thus, the treatment of pre-formed biofilms with AS-48 resulted in a dose- and time-dependent disruption of the biofilm architecture beside the decrease of bacterial viability. Furthermore, we demonstrated the potential of lysozyme to bolster the inhibitory activity of AS-48 against P. acnes, rendering high reductions in the MIC values, even in matrix-growing cultures, according to the results obtained using a range of microscopy and bioassay techniques. The improvement of the activity of AS-48 through its co-formulation with lysozyme may be considered an alternative in the control of P. acnes, especially after proving the absence of cytotoxicity demonstrated by these natural compounds on relevant human skin cell lines. In summary, this study supports that compositions comprising the bacteriocin AS-48 plus lysozyme must be considered as promising candidates for topical applications with medical and pharmaceutical purposes against dermatological diseases such as acne vulgaris.This research was funded by a grant from the Spanish Ministry of Economy and Competitiveness (SAF2013-48971-C2-1-R that included funds from European Regional Development, ERDF), and the Research Group General (BIO160, UGR)
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