87 research outputs found
Novel Biodegradable Composite of Calcium Phosphate Cement and the Collagen I Mimetic P-15 for Pedicle Screw Augmentation in Osteoporotic Bone
Osteoporotic vertebral fractures often necessitate fusion surgery, with high rates of implant failure. We present a novel bioactive composite of calcium phosphate cement (CPC) and the collagen I mimetic P-15 for pedicle screw augmentation in osteoporotic bone. Methods involved expression analysis of osteogenesis-related genes during osteoblastic differentiation by RT-PCR and immunostaining of osteopontin and Ca2+ deposits. Untreated and decalcified sheep vertebrae were utilized for linear pullout testing of pedicle screws. Bone mineral density (BMD) was measured using dual-energy X-ray absorptiometry (DEXA). Expression of ALPI II (p p p p p p p p p = 0.04) with PMMA, and 1252 ± 131 N (p < 0.0078) with CPC-P-15. CPC-P-15 induces osteoblastic differentiation of human MES and improves pullout resistance of pedicle screws in osteoporotic and non-osteoporotic bone
Gebrechlichkeit sowie das Volumen des Muskulus temporalis sind Prädiktoren für das Ansprechen auf die Immuntherapie und das Gesamtüberleben bei Patienten mit Hirnmetastasen bei NSCLC
Image guided implantation of preregistered intracranial catheters on the intensive care unit and in the operation room: a prospective study
Resection margin infiltration after image-guided dural tail resection - prospective evaluation of the Simpson Grade by neuropathological analysis
Evaluation of an accelerated low dose rtPA administration protocol in patients with spontaneous intracerebral hemorrhage
Experience of 4 years robotic-guided spinal instrumentation in the treatment of spondylolisthesis vera
In vitro sonothrombo- and rtPA-lysis in a novel clot model for treatment of spontaneous intracerebral hemorrhage
Bedeutung von Röntgenfunktionsaufnahmen im Vergleich zur Schnittbildgebung mittels CT und MRT in der Detektion einer Instabilität bei Spondylolisthesis der Lendenwirbelsäule
Virustatikatherapie zur Unterdrückung der CMV vermittelten Reduktion des mittleren Überlebens und TMZ-Resistenz beim Glioblastom
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