Quality evaluation of Oral Rehydration Salt (ORS) products marketed in Abuja, Nigeria

Medicine security remains one of the public health challenges in Sub-Saharan Africa as the report by World Health Organization (WHO) shows that 10.5% of medicines in low and middle-income countries worldwide are falsified or substandard. The study aimed to evaluate the quality of Oral Rehydration Salt (ORS) products sold in pharmacy outlets in Abuja, Nigeria. Seventeen different commercial brands of WHO recommended low-osmolarity ORS finished pharmaceutical products (FPP) were randomly selected from pharmacy outlets in the Federal Capital Territory (FCT) and Gwagwalada Area Council in Abuja. They were assessed for quality based on physicochemical properties and the content of active pharmaceutical ingredients in accordance with the International Pharmacopeia (IP) guidelines. The shelf lives of all the samples were valid, and they all met the visual inspection test, labelling, pH (7.4‒8.0 between23.3‒23.9°C) and moisture content (1‒9 mg/g) requirements. The content assay revealed 88.2%, 88.2%, 64.7%, 47.1%, and 35.3% compliance of the samples for glucose, chloride, citrate, sodium and potassium, respectively. Twelve (76.5%) of the brands failed at least one content assay and 8 (47%) had zero potassium content. The study underscores the need for regular, periodic post-market surveillance on essential medicines sold in the Nigerian market

Physicochemical properties of teas sold in Abuja, Nigeria, and evaluation of their caffeine content using HPLC

Tea is commonly consumed in Nigeria. Caffeine, a major constituent in tea, has some beneficial pharmacological properties, but can negatively affect human health if consumed excessively. The objective of the study was to evaluate some physicochemical properties and caffeine content of teas marketed in FCT, Abuja, Nigeria. Ten commercial brands of teas (8 black teas and 2 green teas) were assessed for weight variation, moisture content and pH tests using standard methods. Extraction of caffeine was carried out and the identity determined by thin layer chromatography and melting points, respectively. High performance liquid chromatography (HPLC) method for analysis of caffeine was developed, validated, and applied to determine caffeine content in the tea brands. Results of the weight, moisture content and pH tests of the samples ranged from 2.07–2.33 g, 5.65–11.0 % and 4.9–5.5, respectively. Caffeine was isolated from all the samples and showed same Rf value (0.46) with that of the reference standard. Melting points ranged from 236.0–238.5 °C. Caffeine content ranged from 12.25–21.76 mg/g for black teas and 13.35–15.05 mg/g for green teas. The study provides information on the stability, acidity and caffeine content in some commercially available tea brands

Associations Between Perceived Racial Discrimination, Racial Residential Segregation, and Cancer Screening adherence among Low-income african americans: a Multilevel, Cross-Sectional analysis

OBJECTIVES: African Americans suffer disproportionately from cancer compared to their White counterparts. Racism may be an important determinant, but the literature on its association with cancer screening is limited. We examine associations between racism and cancer screening among a sample of African Americans. DESIGN: Guided by the Public Health Critical Race Praxis and the Behavioral Model of Health Services Use, we conducted a multilevel, cross-sectional study using cancer risk assessment data collected from 405 callers to the 2-1-1 Texas helpline. We merged these data with contextual data from the U.S. Census Bureau. We assessed perceived racial discrimination using the Experiences of Discrimination Scale and racial residential segregation using the Location Quotient for Racial Residential Segregation. We used multilevel regression models to test hypothesized associations between each indicator of racism and four cancer screening adherence outcomes (Pap test, mammography, colorectal cancer screening [CRCS], and any cancer screening). RESULTS: Participants were 18-83 years old (mean = 45 years). Most (81%) were non-adherent to at least one recommended screening. Approximately 42% reported experiencing discrimination and 73% lived in a segregated neighborhood. Discrimination was non-significantly related to lower odds of mammography (aOR = 0.68; 95%CI: 0.38-1.22), CRCS (aOR = 0.79; 95%CI: 0.41-1.52), and any cancer screening adherence (aOR = 0.88; 95%CI: 0.59-1.32). Segregation was related to greater odds of mammography (non-significant; aOR = 1.43; 95%CI: 0.76-2.68) and CRCS (significant; aOR = 2.80; 95%CI: 1.21-6.46) but not associated with any cancer screening. Neither indicator of racism was associated with Pap test screening adherence. CONCLUSIONS: Racism has a nuanced association with cancer screening among low-income, medically underserved African Americans. Specifically, discrimination appears to be associated with lower odds of screening, while segregation may be associated with higher odds of screening in certain situations. Future research is needed to better explicate relations between indicators of racism and cancer screening among African Americans

Racism and Cancer Screening among Low-income, african american Women: a Multilevel, Longitudinal analysis of 2-1-1 Texas Callers

Although racism is increasingly being studied as an important contributor to racial health disparities, its relation to cancer-related outcomes among African Americans remains unclear. The purpose of this study was to help clarify the relation between two indicators of racism-perceived racial discrimination and racial residential segregation-and cancer screening. We conducted a multilevel, longitudinal study among a medically underserved population of African Americans in Texas. We assessed discrimination using the Experiences of Discrimination Scale and segregation using the Location Quotient for Racial Residential Segregation. The outcome examined was any cancer screening completion (Pap test, mammography, and/or colorectal cancer screening) at follow-up (3-10 months post-baseline). We tested hypothesized relations using multilevel logistic regression. We also conducted interaction and stratified analyses to explore whether discrimination modified the relation between segregation and screening completion. We found a significant positive relation between discrimination and screening and a non-significant negative relation between segregation and screening. Preliminary evidence suggests that discrimination modifies the relation between segregation and screening. Racism has a nuanced association with cancer screening among African Americans. Perceived racial discrimination and racial residential segregation should be considered jointly, rather than independently, to better understand their influence on cancer screening behavior

Evaluation of the environmental noise levels in Abuja Municipality using mobile phones

Background: Noise remains a nuisance which impacts negatively on the physical, social and psychological wellbeing of man. It aggravates chronic illnesses like hypertension and other cardiopulmonary diseases. Unfortunately, increased activities from industrialization and technological transfers/drifts have tumultuously led to increased noise pollution in most of our fast growing cities today and hence the need for concerted efforts in monitoring and regulating our environmental noise.Objectives: To assess the equivalent noise level (Leq) in Abuja municipality and promote a simple method for regular assessment of Leq within our environment.Methods: This is a cross-sectional community based study of the environmental Leq of Abuja municipality conducted between January 2014 and January 2016. The city was divided into 12 segments including residential, business and market areas via the Abuja Geographic Information System. The major markets were captured separately on a different scale. Measurements were taken with the mobile phone softwares having validated this withExtech 407730 digital sound level meter, serial no Z310135 . Leq(A) were measured at different points and hours of the day and night. The average Leq(A) were classified according to localities and compared with WHO standard safety levels.Results: LeqD ranged 71-92dB(A); 42-79dB(A) and 69-90dB(A) in business/ parks, residential and market places respectively. The Night measurements were similar 18dB(A)-56dB(A) and the day-night Leq(A)=77.2dB(A) and 90.4dB(A) for residential and business zones.Conclusion: The night noise levels are satisfactory but the day and daynight levels are above the recommended tolerable values by WHO and therefore urgently call for awareness and legislative regulations

Perceived Discrimination and injury at Work: a Cross-Sectional Study among Latino Day Laborers

BACKGROUND: Given the stigma of their undocumented status and their high prevalence of workplace injury, understanding the impact of discrimination on Latino day laborers (LDLs) is a critical public health issue. METHODS: We surveyed LDLs (N = 149) and assessed their sociodemographics, experiences of and perceived reasons for discrimination, and work-related injury. A logistic regression examined the association between discrimination and injury, adjusting for sociodemographics. Next, Chi-square tests identified perceived reasons for discrimination associated with injury which were then included in a second logistic regression to test their association with injury, adjusting for discrimination and sociodemographics. RESULTS: Participants reported a work-related injury (42%) and experiences of discrimination (81%). Discrimination was associated with injury in the first model (aOR = 2.25, p = 0.049), and discrimination attributed to immigration status was associated with injury in the second model (aOR = 5.04, p = 0.019). DISCUSSION: Injury prevention programs should account for perceived mistreatment to reduce LDL risk for injury at work

Structural Racism and Immigrant Health: Exploring the association Between Wage theft, Mental Health, and injury among Latino Day Laborers

BACKGROUND: Although wage theft has been discussed primarily as a labor and human rights issue, it can be conceptualized as an issue of structural racism with important consequences for immigrant health. OBJECTIVES: The objectives of this study were to: 1) identify sociodemographic, employment, and stress-related characteristics that increase Latino day laborers\u27 odds of experiencing wage theft; 2) assess the association between wage theft and serious work-related injury; 3) assess the association between wage theft and three indicators of mental health-depression, social isolation, and alcohol use-as a function of wage theft; and 4) assess serious work-related injury as a function of wage theft controlling for mental health. METHODS: Secondary data analyses were based on survey data collected from 331 Latino day laborers between November 2013 and July 2014. Regression analyses were conducted to test the relationships described above. RESULTS: Approximately 25% of participants reported experiencing wage theft and 20% reported serious work-related injury. Wage theft was associated with working in construction and was initially associated with work-related injury. Wage theft was not significantly associated with mental health indicators. The association between wage theft and injury became non-significant when controlling for the mental health variables. CONCLUSIONS: The hardship and stress associated with wage theft incidents may ultimately lead to more frequent injury. Although we expected an association of wage theft with mental health, we found vulnerability to physical health as indicated by injury incidents. Thus, our basic premise was partially supported: wage theft may act as a stressor that stems from conditions, in part, reflecting structural racism, making workers vulnerable to poorer health

Perceived Discrimination and injury at Work: a Cross-Sectional Study among Latino Day Laborers

BACKGROUND: Given the stigma of their undocumented status and their high prevalence of workplace injury, understanding the impact of discrimination on Latino day laborers (LDLs) is a critical public health issue. METHODS: We surveyed LDLs (N = 149) and assessed their sociodemographics, experiences of and perceived reasons for discrimination, and work-related injury. A logistic regression examined the association between discrimination and injury, adjusting for sociodemographics. Next, Chi-square tests identified perceived reasons for discrimination associated with injury which were then included in a second logistic regression to test their association with injury, adjusting for discrimination and sociodemographics. RESULTS: Participants reported a work-related injury (42%) and experiences of discrimination (81%). Discrimination was associated with injury in the first model (aOR = 2.25, p = 0.049), and discrimination attributed to immigration status was associated with injury in the second model (aOR = 5.04, p = 0.019). DISCUSSION: Injury prevention programs should account for perceived mistreatment to reduce LDL risk for injury at work

Effects of Household Waste Generation, Disposal and Management on Farmers’ Health in Owerri Metropolis of IMO State, Nigeria

The study investigated the effects of household waste generation, disposal and management on farmers' health in Owerri metropolis. It specifically ascertained the socio-economic characteristics of the farmers, identified the types and sources of waste in the study area, examined the waste disposal and management methods in the study area examined the effects of inappropriate waste disposal and ascertained the appropriate waste disposal methods used in the study area. A multi stage sampling technique was used to select one hundred and eight farmers from the three Local Government Area in Owerri metropolis. Data were collected using a validated questionnaire and were analyzed using descriptive statistics tool such as mean, frequency, percentage, and mean scores. Results show that waste is majorly generated from markets and residential homes. Waste disposal methods were mainly burning, landfills and open dumping. Its effects includes destroys the beauty of the environment, blocks gutters and drainage system, pollutes the environment among others. Subsequently, appropriate waste disposal methods in the study area includes burning of waste (29.17%), placing of bins at appropriate places (16.07%). The study recommends amongst others that waste management environmental agency should make waste dumps or receptacles accessible to residents, public campaigns should be embarked upon to educate the citizens on ills of dirty environment