The invisible interior: an investigative approach

Evidence, noun, verb The quality or condition of being evident; clearness, evidentness; in evidence [after French en évidence] actually present; prominent, conspicuous; an appearance from which inferences may be drawn; an indication, mark, sign, token, trace. In his Manhattan Transcripts, 1981, Bernard Tschumi said that architecture ‘cannot be disassociated from the events that happen in it’1. For Tschumi architecture is less about built form and more about interaction – as both material witness and collaborator in the ‘event-world’ that unfolds through and around it. This paper is concerned with methods of capturing this ‘event-world’ where the physical environment – and in particular the interior - operates as a witness to the passing of time, and the transient interactions that take place within in it. Why are some interiors hidden from view or invisible to a public gaze? And what methods of detection might we employ to capture and record the evidence which pertains to these ephemeral moments, preserving them as either material fragments or immaterial data? Sometimes interiors have been designed to be hidden, inaccessible or to be inhabited by very specific users groups. Others are invisible because they are empty - no longer in active use - their intended purpose altered or changed through inhabitation and abandonment. With such interiors there is often no agenda for future possible adaptation; this is the case with the BBC Wing, Alexandra Palace in North London, the site of the first television broadcast in 1936 - currently unoccupied, its destiny uncertain. And Glasgow School of Art - recently devastated by fire, perhaps irretrievably damaging its structure and fabric. Adopting an investigative approach to detecting and narrating the invisible interior, this paper will explore strategies that expose the evidence that is left behind, and assess how new technologies might provide insight into their hidden narratives – atmosphere, emotion, time and memory

'There is no such thing as a boring place': architecture and the built environment as a televisual experience

The essay will look at a number of documentaries that relate to architecture with a view to analysing and defining their characteristic visual strategies, modes of address, and the ways in which they relate to key issues of heritage, innovation and timely controversies over social contexts and use. It will consider the documentary traditions that programmes draw on, and how the characteristics of television shape the mediation of buildings and environments. It will take a particular interest in the part played by expert and polemical commentators, both in terms of their ideological import and their function as expert narrators, advocates and avatars

The edge condition: re-use of industrial heritage on urban waterfronts: a case of London’s second river

This article offers an investigation of the lower Lee Valley and the re-use of selected waterfront industrial heritage buildings. The river creates an edge condition, simultaneously linking and separating the surrounding landscape and framing our experience of this obsolescent infrastructure. These watery fragments of the past slip into view as you descend into the valley towards the River Thames, offering a glimpse of London’s pasts, presents and possible futures. How might we identify an afterlife for this strange environment? And what narratives can be suggested through the adaptive re-use of the waterfront architecture that persists? Water provides a medium for land and buildings, and mediates both as its flows over time and space, eroding and reshaping the built and natural environment as it goes

Educator Perceptions Of A Teacher Evaluation Systems

The research question considered in this project is, what are teacher perceptions of the Educator Effectiveness system of evaluation? To answer this, the author drew on work by Ravitch and Danielson to design a research study to be completed at her school in fall 2017. For the project, she developed the tools for her mixed-methods study, including a quantitative survey and qualitative focus group questions, as well as a PowerPoint presentation to share with the teaching staff at a professional development session at the beginning of the school year in advance of the proposed study. This presentation addresses the purpose, goals, background, and rationale for the research, and employs Knowles’ approach to adult education. In this Capstone, the author documents the implications of and direction for future study of the research topic, as well as challenges and limitations of this work

Missense mutations in the perforin (PRF1) gene as a cause of hereditary cancer predisposition

Perforin, a pore-forming toxin released from secretory granules of NK cells and CTLs, is essential for their cytotoxic activity against infected or cancerous target cells. Bi-allelic loss-of-function mutations in the perforin gene are invariably associated with a fatal immunoregulatory disorder, familial haemophagocytic lymphohistiocytosis type 2 (FHL2), in infants. More recently, it has also been recognized that partial loss of perforin function can cause disease in later life, including delayed onset FHL2 and haematological malignancies. Herein we report a family in which a wide range of systemic inflammatory and neoplastic manifestations have occurred across three generations. We found that disease was linked to two missense perforin gene mutations (encoding A91V, R410W) that cause protein misfolding and partial loss of activity. These cases link the partial loss of perforin function with some solid tumours that are known to be controlled by the immune system, as well as haematological cancers. Our findings also demonstrate that perforin gene mutations can contribute to hereditary cancer predisposition

Penis evolution across species: divergence and diversity

This is the author accepted manuscript. The final version is available from Springer Nature via the DOI in this recordThe penis is an incredibly diverse and rapidly evolving structure, such that even in closely related species that otherwise differ very little in their morphology, penis form can be highly differentiated. Penises are also much more complex than their fundamental function — sperm transfer — would seem to require. The rapid divergent evolution of male structures is typically the signature of traits under sexual selection and the current evidence suggests the penis is no different in this regard. Despite the general agreement that sexual selection is the main driver of penis evolution, many questions about penis evolution remain unresolved. Furthermore, the penis might be an ideal characteristic on which to focus in the drive to link phenotype with genotype

[Abstract] Sentencing intoxicated offenders: does alcoholism excuse drunkenness?

Criminal responsibility is founded on the volitional control of action, yet many offences are committed whilst intoxicated. Alcohol is a widely-used intoxicant known to impair behavioural control and memory, opening the door to claims of partial or absent responsibility. Criminal law rules have developed to resist such claims. In particular, findings of criminal responsibility in intoxicated offenders frequently call on ‘prior fault’ logic: the intoxicated offender may claim to have been irrational, but culpability can be imported from their earlier, rational choice to consume intoxicants (Robinson, 1985). That drunkenness does not excuse derives from an unforced choice to become drunk. Yet this raises questions over the extent to which an alcoholic’s choice to drink is unforced. Current neurobiological models of addiction stress compulsion as a primary component, bringing into question the volitional nature of continued consumption (Volkow & Fowler, 2000; Dalley, Everitt, & Robbins, 2011). At the same time, some legal scholars have noted that the potentially fatal nature of alcoholic withdrawal could likewise undermine suggestion that consumption is voluntary, drawing analogy to a defence of duress where actions have been forced under the threat of death (Husak, 1999; Yaffe, 2013). We asked 290 UK Magistrates to consider a criminal sentencing scenario in which evidence of a defendant’s state of intoxication at the time of the offence was presented in tandem with information that they were either teetotal, a casual drinker or an alcoholic. We found that intoxication reduced blameworthiness for criminal acts if the offender had no previous experience with alcohol whilst, in direct contrast, intoxication served to aggravate offending if the defendant was an alcoholic. The likelihood of our defendant receiving a reduced sentence was over ten times greater in the event that, though intoxicated, they were not also an alcoholic. Leniency was blocked by alcoholism despite Magistrates’ qualitative responses suggesting its understanding as a generally mitigating factor, revealing a disconnect between expressed opinion and sentencing behaviour in practice. Our results indicate that, far from excusing drunkenness, the state of being an alcoholic is more frequently deemed to aggravate offending, being associated with harsher sentencing even where the offence in question was committed whilst sober

Speech Communication

Contains reports on two research projects.United States Air Force, Electronic Systems Division (Contract AF19(628)-3325)National Science Foundation (Grant G-16526)National Institutes of Health (Grant MH-04737-03 and Grant NB-04332-01)National Aeronautics and Space Administration (Grant NsG-496

Speech Communication

Contains research objectives and reports on two research objectives.U.S. Air Force (Air Force Cambridge Research Center, Air Research and Development Command) under Contract AF19(604)-6102National Science Foundatio

Διερεύνηση της δυνατότητας ανίχνευσης και χαρτογράφησης της καλλιέργειας της φακής Εγκλουβής της νήσου Λευκάδας με αντικειμενοστραφή ανάλυση πολυφασματικών απεικονίσεων

The effects of the hydrological regime on temporal changes to physical characteristics of substratum habitat, sediment texture of surface sediments