4,125 research outputs found
CMB Lensing Power Spectrum Biases from Galaxies and Clusters using High-angular Resolution Temperature Maps
The lensing power spectrum from cosmic microwave background (CMB) temperature
maps will be measured with unprecedented precision with upcoming experiments,
including upgrades to ACT and SPT. Achieving significant improvements in
cosmological parameter constraints, such as percent level errors on sigma_8 and
an uncertainty on the total neutrino mass of approximately 50 meV, requires
percent level measurements of the CMB lensing power. This necessitates tight
control of systematic biases. We study several types of biases to the
temperature-based lensing reconstruction signal from foreground sources such as
radio and infrared galaxies and the thermal Sunyaev-Zel'dovich effect from
galaxy clusters. These foregrounds bias the CMB lensing signal due to their
non-Gaussian nature. Using simulations as well as some analytical models we
find that these sources can substantially impact the measured signal if left
untreated. However, these biases can be brought to the percent level if one
masks galaxies with fluxes at 150 GHz above 1 mJy and galaxy clusters with
masses above M_vir = 10^14 M_sun. To achieve such percent level bias, we find
that only modes up to a maximum multipole of l_max ~ 2500 should be included in
the lensing reconstruction. We also discuss ways to minimize additional bias
induced by such aggressive foreground masking by, for example, exploring a
two-step masking and in-painting algorithm.Comment: 14 pages, 14 figures, to be submitted to Ap
Self-monitoring for improving control of blood pressue in patients with hypertension
The objective of this review is to determine the effect of SBPM in adults with hypertension on blood pressure control as compared to OBPM or usual care
Selective Vagus Nerve Stimulation as a Therapeutic Approach for the Treatment of ARDS: A Rationale for Neuro-Immunomodulation in COVID-19 Disease
Acute respiratory distress syndrome (ARDS) is the most severe form of acute lung injury. It is induced by sepsis, aspiration, and pneumonia, including that caused by SARS coronavirus and human influenza viruses. The main pathophysiological mechanism of ARDS is a systemic inflammatory response. Vagus nerve stimulation (VNS) can limit cytokine production in the spleen and thereby dampen any systemic inflammation and inflammation-induced tissue damage in the lungs and other organs. However, the effects of increased parasympathetic outflow to the lungs when non-selective VNS is applied may result in bronchoconstriction, increased mucus secretion and enhance local pulmonary inflammatory activity; this may outweigh the beneficial systemic anti-inflammatory action of VNS. Organ/function-specific therapy can be achieved by imaging of localized fascicle activity within the vagus nerve and selective stimulation of identified organ-specific fascicles. This may be able to provide selective neuromodulation of different pathways within the vagus nerve and offer a novel means to improve outcome in ARDS. This has motivated this review in which we discuss the mechanisms of anti-inflammatory effects of VNS, progress in selective VNS techniques, and a possible application for ARDS.</jats:p
Mechanistic analysis of an asymmetric palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones.
An asymmetric palladium-catalyzed conjugate addition reaction of arylboronic acids to enone substrates was investigated mechanistically. Desorption electrospray ionization coupled to mass spectrometry was used to identify intermediates of the catalytic cycle and delineate differences in substrate reactivity. Our findings provide evidence for the catalytic cycle proceeding through formation of an arylpalladium(II) cation, subsequent formation of an arylpalladium-enone complex, and, ultimately, formation of the new C-C bond. Reaction monitoring in both positive and negative ion modes revealed that 4-iodophenylboronic acid formed a relatively stable trimeric species under the reaction conditions
The Spitzer South Pole Telescope Deep Field Survey: Linking galaxies and halos at z=1.5
We present an analysis of the clustering of high-redshift galaxies in the
recently completed 94 deg Spitzer-SPT Deep Field survey. Applying flux and
color cuts to the mid-infrared photometry efficiently selects galaxies at
in the stellar mass range , making this
sample the largest used so far to study such a distant population. We measure
the angular correlation function in different flux-limited samples at scales
(corresponding to physical distances Mpc) and
thereby map the one- and two-halo contributions to the clustering. We fit halo
occupation distributions and determine how the central galaxy's stellar mass
and satellite occupation depend on the halo mass. We measure a prominent peak
in the stellar-to-halo mass ratio at a halo mass of , 4.5 times higher than the value. This supports
the idea of an evolving mass threshold above which star formation is quenched.
We estimate the large-scale bias in the range and the satellite
fraction to be , showing a clear evolution compared to
. We also find that, above a given stellar mass limit, the fraction of
galaxies that are in similar mass pairs is higher at than at . In
addition, we measure that this fraction mildly increases with the stellar mass
limit at , which is the opposite of the behavior seen at low-redshift.Comment: 32 pages, 22 figures. Published in MNRA
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Availability calculations for nuclear material processing facilities
Methods for developing reliability and maintainability information and integrating it into availability calculations useful in the design and development of nuclear fuel processing facilities are being investigated. Effective availability (actual productive time) is of greater interest than the more traditional operating availability. Actual productive time calculations allow more precise estimates of redundant equipment and surge storage needs. Judgmental estimates of relability and maintainability from personnel involved in equipment design can be used as interim data to guide developmental efforts. These data can be used in computer modeling of integrated process operations. Simulated process operations can be used to study the effects of various redundant equipment and surge storage configurations on plant effective availability
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