3,204 research outputs found

    Unbiased estimates of galaxy scaling relations from photometric redshift surveys

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    Many physical properties of galaxies correlate with one another, and these correlations are often used to constrain galaxy formation models. Such correlations include the color-magnitude relation, the luminosity-size relation, the Fundamental Plane, etc. However, the transformation from observable (e.g. angular size, apparent brightness) to physical quantity (physical size, luminosity), is often distance-dependent. Noise in the distance estimate will lead to biased estimates of these correlations, thus compromising the ability of photometric redshift surveys to constrain galaxy formation models. We describe two methods which can remove this bias. One is a generalization of the V_max method, and the other is a maximum likelihood approach. We illustrate their effectiveness by studying the size-luminosity relation in a mock catalog, although both methods can be applied to other scaling relations as well. We show that if one simply uses photometric redshifts one obtains a biased relation; our methods correct for this bias and recover the true relation

    Relationship between Unconstrained Arm Movements and Single-Neuron Firing in the Macaque Motor Cortex

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    The activity of single neurons in the monkey motor cortex was studied during semi-naturalistic, unstructured arm movements made spontaneously by the monkey and measured with a high resolution three-dimensional tracking system. We asked how much of the total neuronal variance could be explained by various models of neuronal tuning to movement. On average, tuning to the speed of the hand accounted for 1% of the total variance in neuronal activity, tuning to the direction of the hand in space accounted for 8%, a more complex model of direction tuning, in which the preferred direction of the neuron rotated with the starting position of the arm, accounted for 13%, tuning to the final position of the hand in Cartesian space accounted for 22%, and tuning to the final multijoint posture of the arm accounted for 36%. One interpretation is that motor cortex neurons are significantly tuned to many control parameters important in the animal's repertoire, but that different control parameters are represented in different proportion, perhaps reflecting their prominence in everyday action. The final posture of a movement is an especially prominent control parameter although not the only one. A common mode of action of the monkey arm is to maintain a relatively stable overall posture while making local adjustments in direction during performance of a task. One speculation is that neurons in motor cortex reflect this pattern in which direction tuning predominates in local regions of space and postural tuning predominates over the larger workspace

    Possible Origins of the Complex Topographic Organization of Motor Cortex: Reduction of a Multidimensional Space onto a Two-Dimensional Array

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    We propose that some of the features of the topographic organization in motor cortex emerge from a competition among several conflicting mapping requisites. These competing requisites include a somatotopic map of the body, a map of hand location in space, and a partitioning of cortex into regions that emphasize different complex, ethologically relevant movements. No one type of map fully explains the topography; instead, all three influences (and perhaps others untested here) interact to form the topography. A standard algorithm (Kohonen network) was used to generate an artificial motor cortex array that optimized local continuity for these conflicting mapping requisites. The resultant hybrid map contained many features seen in actual motor cortex, including the following: a rough, overlapping somatotopy; a posterior strip in which simpler movements were represented and more somatotopic segregation was observed, and an anterior strip in which more complex, multisegmental movements were represented and the somatotopy was less segregated; a clustering of different complex, multisegmental movements into specific subregions of cortex that resembled the arrangement of subregions found in the monkey; three hand representations arranged on the cortex in a manner similar to the primary motor, dorsal premotor, and ventral premotor hand areas in the monkey; and maps of hand location that approximately matched the maps observed in the monkey

    Possible Origins of the Complex Topographic Organization of Motor Cortex: Reduction of a Multidimensional Space onto a Two-Dimensional Array

    Get PDF
    We propose that some of the features of the topographic organization in motor cortex emerge from a competition among several conflicting mapping requisites. These competing requisites include a somatotopic map of the body, a map of hand location in space, and a partitioning of cortex into regions that emphasize different complex, ethologically relevant movements. No one type of map fully explains the topography; instead, all three influences (and perhaps others untested here) interact to form the topography. A standard algorithm (Kohonen network) was used to generate an artificial motor cortex array that optimized local continuity for these conflicting mapping requisites. The resultant hybrid map contained many features seen in actual motor cortex, including the following: a rough, overlapping somatotopy; a posterior strip in which simpler movements were represented and more somatotopic segregation was observed, and an anterior strip in which more complex, multisegmental movements were represented and the somatotopy was less segregated; a clustering of different complex, multisegmental movements into specific subregions of cortex that resembled the arrangement of subregions found in the monkey; three hand representations arranged on the cortex in a manner similar to the primary motor, dorsal premotor, and ventral premotor hand areas in the monkey; and maps of hand location that approximately matched the maps observed in the monkey

    Proteins and metabolites as indicators of flours quality and nutritional properties of two durum wheat varieties grown in different Italian locations

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    Durum wheat is an important food source in Mediterranean countries, and Italy is the major producer of durum wheat in Europe. The quality of durum wheat flours depends on the type and amount of gluten proteins and starch while flour nutritional value rests on metabolite contents such as polyphenols. In this work, two Italian cultivars, Iride and Svevo, were analyzed for two years (2016–2017) in four Italian regions to explore how the environment affects: (i) reserve proteome; (ii) starch content and composition; and (iii) free, conjugated, bound phenolics and antioxidant capacity. The impact of environmental and meteorological conditions was significant for many traits. Regardless of the cultivation site, in 2017, a year with less rainfall and a higher temperature during grain filling, there was an increase in low molecular weight glutenins, in the glutenin/gliadin ratio and in the A–type starch granules size, all parameters of higher technological quality. In the same year, the cultivars showed higher amounts of polyphenols and antioxidant capacity. In conclusion, the two wheat cultivars, selected for their medium to high yield and their good quality, had higher performances in 2017 regardless of their sowing locations

    Mapping Behavioral Repertoire onto the Cortex

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    A traditional view of the motor cortex in the primate brain is that it contains a map of the body arranged across the cortical surface. This traditional topographic scheme, however, does not capture the actual pattern of overlaps, fractures, re-representations, and multiple areas separated by fuzzy borders. Here, we suggest that the organization of the motor cortex, premotor cortex, supplementary motor cortex, frontal eye field, and supplementary eye field can in principle be understood as a best-fit rendering of the motor repertoire onto the two-dimensional cortical sheet in a manner that optimizes local continuity

    Ethical and Psychosocial Aspects of HIV/AIDS

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    On the functional test of the BTB logic in pipelined and superscalar processors

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    Electronic systems are increasingly used for safety-critical applications, where the effects of faults must be taken under control and hopefully avoided. For this purpose, test of manufactured devices is particularly important, both at the end of the production line and during the operational phase. This paper describes a method to test the logic implementing the Branch Prediction Unit in pipelined and superscalar processors when this follows the Branch Target Buffer (BTB) architecture; the proposed approach is functional, i.e., it is based on forcing the processor to execute a suitably devised test program and observing the produced results. Experimental results are provided on the DLX processor, showing that the method can achieve a high value of stuck-at fault coverage while also testing the memory in the BT
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