A microfluidic device for the study of the orientational dynamics of microrods

We describe a microfluidic device for studying the orientational dynamics of microrods. The device enables us to experimentally investigate the tumbling of microrods immersed in the shear flow in a microfluidic channel with a depth of 400 mu and a width of 2.5 mm. The orientational dynamics was recorded using a 20 X microscopic objective and a CCD camera. The microrods were produced by shearing microdroplets of photocurable epoxy resin. We show different examples of empirically observed tumbling. On the one hand we find that short stretches of the experimentally determined time series are well described by fits to solutions of Jeffery's approximate equation of motion [Jeffery, Proc. R. Soc. London. 102 (1922), 161-179]. On the other hand we find that the empirically observed trajectories drift between different solutions of Jeffery's equation. We discuss possible causes of this orbit drift.Comment: 11 pages, 8 figure

Sperm morphology in Estonian and Tori Breed Stallions

The standard procedure for assessing the breeding potential of a stallion includes the parameter total number of spermatozoa classified as morphologically normal. This study investigated sperm morphology of fresh semen in randomly chosen Estonian (E, n = 8) and Tori (T, n = 7) breed stallions with proven fertility. Two ejaculates were examined from each stallion. An aliquot from each ejaculate was fixed in 1 mL formol-saline immediately after collection and examined with phase-contrast microscope at a magnification 1000× for all types of morphological abnormalities. Furthermore smears were prepared and stained according to Williams (carbolfuchsin-eosin) for a more detailed examination of the sperm heads with light microscope at a magnification 1000×. Analysis of variance was applied to the data, and results are presented as LSmeans (± SE). One T stallion that had a disturbance in the spermatogenesis and one 22-year-old E stallion were not included in the analyses. The T stallions had on average 57.5 ± 4.1% and the E-stallions 74.4 ± 3.8% morphologically normal spermatozoa (p = 0.012). In 4 of 7 T stallions and 7 of 8 E stallions both ejaculates had >50% morphologically normal spermatozoa. There was a significant difference between breeds in mean percentage of proximal droplets (17.3 ± 2.7% and 2.9 ± 2.5% for T and E stallions, respectively; p = 0.003)

Meissner effect in honeycomb arrays of multi-walled carbon nanotubes

We report Meissner effect for type-II superconductors with a maximum Tc of 19 K, which is the highest value among those in new-carbon related superconductors, found in the honeycomb arrays of multi-walled CNTs (MWNTs). Drastic reduction of ferromagnetic catalyst and efficient growth of MWNTs by deoxidization of catalyst make the finding possible. The weak magnetic anisotropy, superconductive coherence length (- 7 nm), and disappearance of the Meissner effect after dissolving array structure indicate that the graphite structure of an MWNT and those intertube coupling in the honeycomb array are dominant factors for the mechanism.Comment: 6 page

Modified Spin Wave Thoery of the Bilayer Square Lattice Frustrated Quantum Heisenberg Antiferromagnet

The ground state of the square lattice bilayer quantum antiferromagnet with nearest and next-nearest neighbour intralayer interaction is studied by means of the modified spin wave method. For weak interlayer coupling, the ground state is found to be always magnetically ordered while the quantum disordered phase appear for large enough interlayer coupling. The properties of the disordered phase vary according to the strength of the frustration. In the regime of weak frustration, the disordered ground state is an almost uncorrelated assembly of interlayer dimers, while in the strongly frustrated regime the quantum spin liquid phase which has considerable N\'eel type short range order appears. The behavior of the sublattice magnetization and spin-spin correlation length in each phase is discussed.Comment: 15 pages, revtex, figures upon reques

Direct Calculation of the Spin Stiffness in the J1J_1--J2J_2 Heisenberg Antiferromagnet

We calculate the spin stiffness $\rho_s$ for the frustrated spin-$\frac{1}{2}$ Heisenberg antiferromagnet on a square lattice by exact diagonalizations on finite clusters of up to $36$ sites followed by extrapolations to the thermodynamic limit. For the non-frustrated case, we find that $\rho_s = (0.183\pm 0.003)J_1$, in excellent agreement with the best results obtained by other means. Turning on frustration, the extrapolated stiffness vanishes for $0.4 \lesssim J_2/J_1 \lesssim 0.6$. In this intermediate region, the finite-size scaling works poorly -- an additional sign that their is neither N\'eel nor collinear magnetic order. Using a hydrodynamic relation, and previous results for the transverse susceptibility, we also estimate the spin-wave velocity in the N\'eel-ordered region.Comment: 4 pages, uuencoded compressed ps-file (made with uufiles

The Feasibility of Societal Cost Equivalence between Robotic Hysterectomy and Alternate Hysterectomy Methods for Endometrial Cancer

Objectives. We assess whether it is feasible for robotic hysterectomy for endometrial cancer to be less expensive to society than traditional laparoscopic hysterectomy or abdominal hysterectomy. Methods. We performed a retrospective cohort analysis of patient characteristics, operative times, complications, and hospital charges from all (n = 234) endometrial cancer patients who underwent hysterectomy in 2009 at our hospital. Per patient costs of each hysterectomy method were examined from the societal perspective. Sensitivity analysis and Monte Carlo simulation were performed using a cost-minimization model. Results. 40 (17.1%) of hysterectomies for endometrial cancer were robotic, 91 (38.9%), were abdominal, and 103 (44.0%) were laparoscopic. 96.3% of the variation in operative cost between patients was predicted by operative time (R = 0.963, P < 0.01). Mean operative time for robotic hysterectomy was significantly longer than other methods (P < 0.01). Abdominal hysterectomy was consistently the most expensive while the traditional laparoscopic approach was consistently least expensive. The threshold in operative time that makes robotic hysterectomy cost equivalent to the abdominal approach is within the range of our experience. Conclusion. It is feasible for robotic hysterectomy to be less expensive than abdominal hysterectomy, but unlikely for robotic hysterectomy to be less expensive than traditional laparoscopy

Topological quantum memory

We analyze surface codes, the topological quantum error-correcting codes introduced by Kitaev. In these codes, qubits are arranged in a two-dimensional array on a surface of nontrivial topology, and encoded quantum operations are associated with nontrivial homology cycles of the surface. We formulate protocols for error recovery, and study the efficacy of these protocols. An order-disorder phase transition occurs in this system at a nonzero critical value of the error rate; if the error rate is below the critical value (the accuracy threshold), encoded information can be protected arbitrarily well in the limit of a large code block. This phase transition can be accurately modeled by a three-dimensional Z_2 lattice gauge theory with quenched disorder. We estimate the accuracy threshold, assuming that all quantum gates are local, that qubits can be measured rapidly, and that polynomial-size classical computations can be executed instantaneously. We also devise a robust recovery procedure that does not require measurement or fast classical processing; however for this procedure the quantum gates are local only if the qubits are arranged in four or more spatial dimensions. We discuss procedures for encoding, measurement, and performing fault-tolerant universal quantum computation with surface codes, and argue that these codes provide a promising framework for quantum computing architectures.Comment: 39 pages, 21 figures, REVTe

Endometriosis classification, staging and reporting systems: a review on the road to a universally accepted endometriosis classification,

BACKGROUND: In the field of endometriosis, several classification, staging and reporting systems have been developed. However, endometriosis classification, staging and reporting systems that have been published and validated for use in clinical practice have not been systematically reviewed up to now. OBJECTIVES: The aim of the current review is to provide a historical overview of these different systems based on an assessment of published studies. MATERIALS AND METHODS: A systematic Pubmed literature search was performed. Data were extracted and summarised. RESULTS: Twenty-two endometriosis classification, staging and reporting systems have been published between 1973 and 2021, each developed for specific and different purposes. There is still no international agreement on how to describe the disease. Studies evaluating different systems are summarised showing a discrepancy between the intended and the evaluated purpose, and a general lack of validation data confirming a correlation with pain symptoms or quality of life for any of the current systems. A few studies confirm the value of the Enzian system for surgical description of deep endometriosis. With regards to infertility, the endometriosis fertility index has been confirmed valid for its intended purpose. CONCLUSIONS: Of the 22 endometriosis classification, staging and reporting systems identified in this historical overview, only a few have been evaluated, in 46 studies, for the purpose for which they were developed. It can be concluded that there is no international agreement on how to describe endometriosis or how to classify it, and that most classification/staging systems show no or very little correlation with patient outcomes. WHAT IS NEW? This overview of existing systems is a first step in working towards a universally accepted endometriosis classification

Schwinger-boson approach to quantum spin systems: Gaussian fluctuactions in the "natural" gauge

We compute the Gaussian-fluctuation corrections to the saddle-point Schwinger-boson results using collective coordinate methods. Concrete application to investigate the frustrated J1-J2 antiferromagnet on the square lattice shows that, unlike the saddle-point predictions, there is a quantum nonmagnetic phase for 0.53 < J2/J1 < 0.64. This result is obtained by considering the corrections to the spin stiffness on large lattices and extrapolating to the thermodynamic limit, which avoids the infinite-lattice infrared divergencies associated to Bose condensation. The very good agreement of our results with exact numerical values on finite clusters lends support to the calculational scheme employed.Comment: 4 pages, Latex, 3 figures included as eps files,minor correction

Elevated visual dependency in young adults after chemotherapy in childhood

Chemotherapy in childhood can result in long-term neurophysiological side-effects, which could extend to visual processing, specifically the degree to which a person relies on vision to determine vertical and horizontal (visual dependency). We investigated whether adults treated with chemotherapy in childhood experience elevated visual dependency compared to controls and whether any difference is associated with the age at which subjects were treated. Visual dependency was measured in 23 subjects (mean age 25.3 years) treated in childhood with chemotherapy (CTS) for malignant, solid, non-CNS tumors. We also stratified CTS into two groups: those treated before 12 years of age and those treated from 12 years of age and older. Results were compared to 25 healthy, age-matched controls. The subjective visual horizontal (SVH) and vertical (SVV) orientations was recorded by having subjects position an illuminated rod to their perceived horizontal and vertical with and without a surrounding frame tilted clockwise and counter-clockwise 20° from vertical. There was no significant difference in rod accuracy between any CTS groups and controls without a frame. However, when assessing visual dependency using a frame, CTS in general (p = 0.006) and especially CTS treated before 12 years of age (p = 0.001) tilted the rod significantly further in the direction of the frame compared to controls. Our findings suggest that chemotherapy treatment before 12 years of age is associated with elevated visual dependency compared to controls, implying a visual bias during spatial activities. Clinicians should be aware of symptoms such as visual vertigo in adults treated with chemotherapy in childhood