Open Transactions on Shared Memory

Transactional memory has arisen as a good way for solving many of the issues of lock-based programming. However, most implementations admit isolated transactions only, which are not adequate when we have to coordinate communicating processes. To this end, in this paper we present OCTM, an Haskell-like language with open transactions over shared transactional memory: processes can join transactions at runtime just by accessing to shared variables. Thus a transaction can co-operate with the environment through shared variables, but if it is rolled-back, also all its effects on the environment are retracted. For proving the expressive power of TCCS we give an implementation of TCCS, a CCS-like calculus with open transactions

Three-body Thomas-Ehrman shifts of analog states of 17^{17}Ne and 17^{17}N

The lowest-lying states of the Borromean nucleus $^{17}$Ne ($^{15}$O+$p$ + $p$) and its mirror nucleus $^{17}$N ($^{15}$N+$n$ + $n$) are compared by using the hyperspheric adiabatic expansion. Three-body resonances are computed by use of the complex scaling method. The measured size of $^{15}$O and the low-lying resonances of $^{16}$F ($^{15}$O+$p$) are first used as constraints to determine both central and spin-dependent two-body interactions. The interaction obtained reproduces relatively accurately both experimental three-body spectra. The Thomas-Ehrman shifts, involving excitation energy differences, are computed and found to be less than 3% of the total Coulomb energy shift for all states.Comment: 9 pages, 3 postscript figures, revtex style. To be published in Phys. Rev.

Coexistence of bulk and surface states probed by Shubnikov-de Haas oscillations in Bi2_2Se3_3 with high charge-carrier density

Topological insulators are ideally represented as having an insulating bulk with topologically protected, spin-textured surface states. However, it is increasingly becoming clear that these surface transport channels can be accompanied by a finite conducting bulk, as well as additional topologically trivial surface states. To investigate these parallel conduction transport channels, we studied Shubnikov-de Haas oscillations in Bi$_2$Se$_3$ thin films, in high magnetic fields up to 30 T so as to access channels with a lower mobility. We identify a clear Zeeman-split bulk contribution to the oscillations from a comparison between the charge-carrier densities extracted from the magnetoresistance and the oscillations. Furthermore, our analyses indicate the presence of a two-dimensional state and signatures of additional states the origin of which cannot be conclusively determined. Our findings underpin the necessity of theoretical studies on the origin of and the interplay between these parallel conduction channels for a careful analysis of the material's performance.Comment: Manuscript including supplemental materia

Oscillatory Control over Representational States in Working Memory

In the visual world, attention is guided by perceptual goals activated in visual working memory (VWM). However, planning multiple-task sequences also requires VWM to store representations for future goals. These future goals need to be prevented from interfering with the current perceptual task. Recent findings have implicated neural oscillations as a control mechanism serving the implementation and switching of different states of prioritization of VWM representations. We review recent evidence that posterior alpha-band oscillations underlie the flexible activation and deactivation of VWM representations and that frontal delta-to-theta-band oscillations play a role in the executive control of this process. That is, frontal delta-to-theta appears to orchestrate posterior alpha through long-range oscillatory networks to flexibly set up and change VWM states during multitask sequences

Crisis signaling: how Italy's coronavirus lockdown affected incumbent support in other European countries

The COVID-19 pandemic is an unparalleled global crisis. Yet, despite the grave adversity faced by citizens, incumbents around the world experienced a boost in popularity during the onset of the outbreak. In this study, we examine how the response to the COVID-19 outbreak in one country affected incumbent support in other countries. Specifically, we leverage the fact that the first country-wide lockdown on European soil, in Italy on 9 March 2020, happened during the fieldwork of surveys conducted in four other European countries, France, Germany, Poland and Spain. This allows us to examine how an event abroad that alerted citizens to an imminent crisis-prior to a similar domestic government response-influenced incumbent support. Our results indicate a crisis signal effect of Italy's COVID-19 lockdown, as support for the incumbent increased domestically in other European countries after the lockdown. Importantly, these findings suggest that incumbents can benefit from a crisis unfolding in other countries, even when their own performance in response to the same crisis is not yet fully clear. They illustrate the importance of developments abroad for incumbent approval and the difficulty facing citizens seeking to disentangle performance signals from exogenous shocks

Conversion of the prodrug etoposide phosphate to etoposide in gastric juice and bile.

Etoposide phosphate is a water-soluble prodrug of etoposide. It was expected that this prodrug could be used to overcome the solubility limitations and erratic bioavailability of oral etoposide. To investigate the possibility of prodrug conversion to etoposide within the gastrointestinal lumen, etoposide phosphate was dissolved in water and incubated with human gastric juice or human bile in vitro. Samples were collected during 150 min and analysed for etoposide concentration with high-performance liquid chromatography. Conversion of prodrug to etoposide during incubation with gastric juice was negligible. There was significant conversion during incubation with bile at pH 7-8. The percentage of prodrug converted to etoposide at pH 8 after 60 min was 78 +/- 18% (mean +/- S.D.) for a 0.1 mg ml-1 prodrug solution and 36 +/- 26% for 0.5 mg ml-1. At pH 7, after 60 min 22% of prodrug was converted to etoposide when incubated at 0.1 mg ml-1 and 10% at 0.5 mg ml-1. No conversion was found after inactivation of alkaline phosphate (AP) by overnight heating of bile at 65 degrees C or by the addition of disodium edetate to the bile. In conclusion, because of AP in bile, variable conversion of etoposide phosphate to etoposide can be expected within the intestinal lumen after oral administration. This could have important pharmacokinetic consequences