480 research outputs found

    Development of trade unionism in India

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    Thesis (M.B.A.)--Boston Universit

    Application of a Third Order Upwind Scheme to Viscous Flow over Clean and Iced Wings

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    A 3-D compressible Navier-Stokes solver has been developed and applied to 3-D viscous flow over clean and iced wings. This method uses a third order accurate finite volume scheme with flux difference splitting to model the inviscid fluxes, and second order accurate symmetric differences to model the viscous terms. The effects of turbulence are modeled using a Kappa-epsilon model. In the vicinity of the sold walls the kappa and epsilon values are modeled using Gorski's algebraic model. Sampling results are presented for surface pressure distributions, for untapered swept clean and iced wings made of NACA 0012 airfoil sections. The leading edge of these sections is modified using a simulated ice shape. Comparisons with experimental data are given

    Inverse relationship between serum high density lipoprotein and negative syndrome in antipsychotic-naive schizophrenia

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    Background: Recent literature suggests a role for apolipoprotein L (apoL) aberrations in the pathogenesis of schizophrenia. ApoL is almost exclusively associated with apolipoprotein A-I in high-density lipoproteins (HDLs). The objective of this study was to examine the correlation between symptom scores and serum HDL in antipsychotic-naive schizophrenia patients. Methods: In this cross-sectional study, 60 antipsychotic-naive schizophrenia patients were systematically examined for their symptom scores, with good inter-rater reliability. Concurrently, an overnight fasting serum lipid profile from these patients was assessed. Results: Serum HDL had a significant inverse correlation with a total negative syndrome score (ρ=−0.43; p=0.001). Conclusions: The study observation supports the potential role for HDL abnormalities in the genesis of negative symptoms in schizophrenia. Clin Chem Lab Med 2010;48:95–8.Peer Reviewe

    Metasurface-based Mueller Matrix Microscope

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    In conventional optical microscopes, image contrast of objects mainly results from the differences in light intensity and/or color. Muller matrix optical microscopes (MMMs), on the other hand, can provide significantly enhanced image contrast and rich information about objects by analyzing their interactions with polarized light. However, state-of-art MMMs are fundamentally limited by bulky and slow polarization state generators and analyzers. Here, we demonstrated the feasibility of applying metasurfaces to enable a fast and compact MMM, i.e., Meta-MMM. We developed a dual-color MMM, in both reflection and transmission modes, based on a chip-integrated high-speed (>20fps) metasurface polarization state analyzer (Meta-PSA) and realized high measurement accuracy for Muller matrix (MM) imaging. We then applied our Meta-MMM to nanostructure characterization, surface morphology analysis and discovered birefringent structures in honeybee wings. Our meta-MMMs hold the promise to revolutionize various applications from biological imaging, medical diagnosis, material characterization to industry inspection and space exploration

    Silicon based substrate with calcium aluminosilicate environmental/thermal barrier layer

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    A barrier layer for a silicon containing substrate which inhibits the formation of gaseous species of silicon when exposed to a high temperature aqueous environment comprises a calcium alumino silicate

    Silicon based substrate with calcium aluminosilicate/thermal barrier layer

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    A barrier layer for a silicon containing substrate which inhibits the formation of gaseous species of silicon when exposed to a high temperature aqueous environment comprises a calcium alumino silicate

    Auxiliary subunit regulation of high-voltage activated calcium channels expressed in mammalian cells

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    The effects of auxiliary calcium channel subunits on the expression and functional properties of high-voltage activated (HVA) calcium channels have been studied extensively in the Xenopus oocyte expression system, but are less completely characterized in a mammalian cellular environment. Here, we provide the first systematic analysis of the effects of calcium channel beta and alpha(2)-delta subunits on expression levels and biophysical properties of three different types (Ca(v)1.2, Ca(v)2.1 and Ca(v)2.3) of HVA calcium channels expressed in tsA-201 cells. Our data show that Ca(v)1.2 and Ca(v)2.3 channels yield significant barium current in the absence of any auxiliary subunits. Although calcium channel beta subunits were in principle capable of increasing whole cell conductance, this effect was dependent on the type of calcium channel alpha(1) subunit, and beta(3) subunits altogether failed to enhance current amplitude irrespective of channel subtype. Moreover, the alpha(2)-delta subunit alone is capable of increasing current amplitude of each channel type examined, and at least for members of the Ca(v)2 channel family, appears to act synergistically with beta subunits. In general agreement with previous studies, channel activation and inactivation gating was regulated both by beta and by alpha(2)-delta subunits. However, whereas pronounced regulation of inactivation characteristics was seen with the majority of the auxiliary subunits, effects on voltage dependence of activation were only small (< 5 mV). Overall, through a systematic approach, we have elucidated a previously underestimated role of the alpha(2)-delta(1) subunit with regard to current enhancement and kinetics. Moreover, the effects of each auxiliary subunit on whole cell conductance and channel gating appear to be specifically tailored to subsets of calcium channel subtypes
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