710 research outputs found
The Effect of flashing in reducing the tonal range of a transparency for photomechanical reproduction
Photographic processing and lithographic printing reproduction are two different processes. In photography, the transparency reproduces the original scene in continuous tone. Whereas, in lithographic printing, the reproduction is a result of an all-or-nothing process. A transparency may have a tonal range that exceeds the range that can be reproduced in lithographic printing. So tone compression is performed on transparencies that exceed the tonal range for printing. Avoiding tone compression during lithographic production results in considerable savings in cost and time. One of the methods to reduce tonal range is for the photographer to understand the relationship between emulsion flashing and the tonal range of transparencies. Flashing is the process of projecting nonimage white light to the film emulsion either before or after exposure, but prior to processing. This study investigated the relationship between flashing and exposure for a transparency which would reduce its tonal range and make it suitable for printing. The hypotheses under investigation were: (1) it is possible to flash Ektachrome transparency film by a predetermined amount of light to produce a desired reduction in the tonal range of a transparency, making it more acceptable to the printing range of lithographic printing when using coated paper; (2) the post-flashing technique produces the most acceptable result in achieving the desired tonal range as compared to the pre-flashing technique; (3) the flashing technique produces the same result in a transparency as the image prepared by the use of adjusting the lighting ratio in measured photography. An experimental investigation was conducted. A setup consisting of standard scales was photographed at various exposures and different degrees of flashing. The photography was performed using a 4X5 camera. The setup was illuminated at 45 angles by means of two strobe lights. Exposure was controlled by altering the aperture opening of the lens or fstop. The degree of flashing was determined by pre-exposing or post-exposing the Ektachrome transparency film emulsion to non-image white light through sheets of parchment paper placed at a distance of three inches from the camera lens. The amount of light that could reach the lens during flashing was controlled by varying the number of sheets of parchment paper. Thirty-two transparencies were photographed. The transparencies were processed by E-6 process. The tonal ranges of the transparencies were measured by means of a transmission densitometer. A visual test was conducted to determine the visual appeal of the transparencies by professionals in the field of photography and printing. The outcome of the experimental investigation showed that the tonal range of a transparency is reduced when the film emulsion is flashed. The results suggest that preflashing by an amount of a little over one-third of the light required for normal exposure and then exposing the film to the subject or setup at one and a half stop below the normal exposure produces transparencies that have a tonal range within the limits of lithographic printing and that are visually appealing. It was also shown that pre-flashing the film had a greater effect on reducing the tonal range than post-flashing. Moreover, the flashing technique was compared with methods used to reduce the tonal range by adjusting the lighting ratio. Based on these results, the first hypothesis was confirmed, the second was rejected, and the third was qualitatively accepte
Spectrum of Paediatric Lysosomal Storage Disorders in Oman
Objectives: The aim of this study was to look at the spectrum of paediatric lysosomal disorders in Oman. Lysosomal storage disorders (LSDs) are a heterogeneous group of inherited metabolic diseases. Few studies on the birth prevalence and prevalence of LSDs have been reported from the Arabian Peninsula. Methods: We studied 86 children with LSDs diagnosed over a period of nine years, from June 1998 to May 2007. Detailed clinical data, including age of onset, sex, age and mode of first presentation, and presence of consanguinity were collected. Results: Our data showed the combined birth prevalence for all LSDs in Oman to be around 1 in 4,700 live births. Sphingolipidoses was the most common group of disorder encountered (47.7%), followed by neuronal ceroid lipofuscinoses (NCL) (23.2%) and mucopolysaccharidoses (MPS) (23.2%). The proportion of consanguineous marriages in our series was found to be 87.5%. Conclusion: Our data represent the birth prevalence and clinicalspectrum of such disorders in Oman, one of the highly consanguineous societies in the Middle East.
Impact of earnings components on future profitability of banking and insurance companies in Jordan
This study aimed to examine the impact of a firm’s total accruals and operating cash flows on future profitability (one-year-ahead ROA) using a static model on unbalanced panel data for all the (15) banks and (18) insurance companies listed on the Amman Stock Exchange from 2002 to 2019. The final sample of the study, for analysis, consisted of 280 observations taken from the banking sector and 410 observations from the insurance sector. The pooled sample of banks’ observations showed no significant impact of a firm’s total accruals and operating cash flows on one-year-ahead ROA. This result is consistent with previous studies’ results, which are still under debate, especially in developed countries. The investors of the Jordanian banks are not counting on the accrual earnings components, which are affected by the different estimation procedures of GAAP and managerial discretion. The pooled sample of the insurance companies’ observations showed a significant impact of a firm’s total accruals and operating cash flows on one-year-ahead ROA. The result showed a higher variable value of a firm’s operating cash flow than the firm’s total accruals for the pooled sample of insurance companies. This result indicates a more incrementally negative relation between the growth in operating assets and a one-year-ahead ROA in addition to the probable impact of the lower rate of economic profits and the conservative bias in accounting
Glycogen Synthase Kinase (GSK) 3β phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation to activate rDNA transcription in early G1 cells
Nuclear myosin 1c (NM1) mediates RNA polymerase I (pol I) transcription activation and cell cycle progression by facilitating PCAF-mediated H3K9 acetylation, but the molecular mechanism by which NM1 is regulated remains unclear. Here, we report that at early G1 the glycogen synthase kinase (GSK) 3β phosphorylates and stabilizes NM1, allowing for NM1 association with the chromatin. Genomic analysis by ChIP-Seq showed that this mechanism occurs on the rDNA as active GSK3β selectively occupies the gene. ChIP assays and transmission electron microscopy in GSK3β-/- mouse embryonic fibroblasts indicated that at G1 rRNA synthesis is suppressed due to decreased H3K9 acetylation leading to a chromatin state incompatible with transcription. We found that GSK3β directly phosphorylates the endogenous NM1 on a single serine residue (Ser-1020) located within the NM1 C-terminus. In G1 this phosphorylation event stabilizes NM1 and prevents NM1 polyubiquitination by the E3 ligase UBR5 and proteasome-mediated degradation. We conclude that GSK3β-mediated phosphorylation of NM1 is required for pol I transcription activation
Fast Computing Betweenness Centrality with Virtual Nodes on Large Sparse Networks
Betweenness centrality is an essential index for analysis of complex networks. However, the calculation of betweenness centrality is quite time-consuming and the fastest known algorithm uses time and space for weighted networks, where and are the number of nodes and edges in the network, respectively. By inserting virtual nodes into the weighted edges and transforming the shortest path problem into a breadth-first search (BFS) problem, we propose an algorithm that can compute the betweenness centrality in time for integer-weighted networks, where is the average weight of edges and is the average degree in the network. Considerable time can be saved with the proposed algorithm when , indicating that it is suitable for lightly weighted large sparse networks. A similar concept of virtual node transformation can be used to calculate other shortest path based indices such as closeness centrality, graph centrality, stress centrality, and so on. Numerical simulations on various randomly generated networks reveal that it is feasible to use the proposed algorithm in large network analysis
Pan-genome inversion index reveals evolutionary insights into the subpopulation structure of Asian rice
Comparative Study of Clinical and Radiological Outcomes of Unconstrained Bicondylar Total Knee Endoprostheses with Anti-allergic Coating
Risk factors for pre-term birth in Iraq: a case-control study
BACKGROUND: Preterm birth (PTB)is a major clinical problem associated with perinatal mortality and morbidity. The aim of the present study is to identify risk factors associated with PTB in Mosul, Iraq. METHODS: A case-control study was conducted in Mosul, Iraq, from 1(st )September, 2003 to 28(th )February, 2004. RESULTS: A total of 200 cases of PTB and 200 controls of full-term births were screened and enrolled in the study. Forward logistic regression analysis was used in the analysis. Several significant risk associations between PTB and the following risk factors were identified: poor diet (OR = 4.33), heavy manual work (OR = 1.70), caring for domestic animals (OR = 5.06), urinary tract infection (OR = 2.85), anxiety (OR = 2.16), cervical incompetence (OR = 4.74), multiple pregnancies (OR = 7.51), direct trauma to abdomen (OR = 3.76) and abortion (OR = 6.36). CONCLUSION: The main determinants of PTB in Iraq were low socio-economic status and factors associated with it, such as heavy manual work and caring for domestic animals, in addition to urinary tract infections and poor obstetric history
ENVIRONMENTAL ASSESSMENT OF AL-HILLAH RIVER POLLUTION AT BABIL GOVERNORATE (IRAQ)
In this study, the environmental characteristics of Al-Hillah River were studied using geoinformatics applications, which is one of the geospatial techniques (GST). Applying this methodology, a geographic information system was developed, and it was supplied with laboratory data for the physical and chemical properties of 16 parameters for 2021. These data were linked to their spatial locations, using radar imagery of the Digital Elevation Model (Shuttle Radar Topography Mission), and Landsat ETM+7 satellite image. The results indicated that Al-Hillah River was affected by the liquid discharges of factories, cities, and farms spread on its sides, especially in the cities of Sadat Al-Hindiya, Al-Hillah, and Al-Hashimiyah. The seasonal changes in the climate affected some characteristics, including water temperature, pH, turbidity, total dissolved solids, and total hardness. The study showed that the concentration of sulfate (SO4) has risen above the permissible limits for the waters of Iraqi rivers. There are relatively high hardness and alkalinity values, but they were within the permissible limits. The study also showed that most of the results of environmental parameters that were used in the laboratory, were within the permissible limits of Iraqi water, except for sulfates. The justification for conducting this study is to help government agencies and decision-makers to adopt a correct vision for development projects that serve Babil Governorate. Also, it is the first time that the environmental characteristics of Al-Hillah River are studied using geoinformatics applications
A collection of annotated and harmonized human breast cancer transcriptome datasets, including immunologic classification
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