Akagi M

Bader R

Bellamy N

Bergschmidt P

Bin SI

Brinker MR

Christoph Schulze

Eben R

Fink U

Guenther Kundt

Innocenti B

Kim YH

Kircher J

Krenn V

Majima T

Miner AL

Philipp Bergschmidt

Plitz W

Raimondi MT

Rainer Bader

Ranawat CS

Rau R

Susanne Finze

Thomas P

Thull R

Ware JE

Willmann G

Wolfram Mittelmeier

Open Orthopaedics Journal

English

PubMed


                    Background:
                    Hypersensitivity reactions to implant materials have become more important in total knee replacement (TKR). The purpose of this retrospective comparative study was to evaluate the clinical and radiological outcomes of unconstrained bicondylar total knee prostheses with and without anti-allergic titanium(niobium)nitrite (Ti(Nb)N) coating.
                
                
                    Methods:
                    Twenty-four patients (25 TKRs) underwent a preoperative clinical evaluation and then a postoperative evaluation after 26.2 months in the allergy group treated with coated implants (n=13 implants) and after 24.5 months in the control group treated with uncoated implants but identical geometry (n=12) using HSS, WOMAC and SF-36 scores. Radiological evaluations were performed using standard anterior-posterior (a.p.) and lateral X-rays.
                
                
                    Results:
                    During follow-up two patients of the allergy group had to undergo revision surgery due to non-implant-related reasons. A comparative analysis of both study groups showed a significant difference in the HSS scores at both evaluation time points (MW test p≤0.050); these findings are remarkable since the control group had a significantly lower score preoperatively (54.0 vs 65.0 points) and a significantly higher score (82.5 vs 75.0 points) postoperatively. The preoperative and postoperative WOMAC and SF-36 scores were comparable in both groups (MW test p≥0.052), although the postoperative increase in the score for the allergy group was lower. The radiological results were comparable in both groups and were unlikely to influence the results.
                
                
                    Conclusions:
                    This clinical study demonstrates the restricted outcome in postoperative function and quality of life in the allergy group compared to the control group.
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Comparative Study of Clinical and Radiological Outcomes of Unconstrained Bicondylar Total Knee Endoprostheses with Anti-allergic Coating

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