844 research outputs found
Hyperonic mixing in five-baryon double-strangeness hypernuclei in a two-channel treatment
Properties of hypernuclei H and He are studied in a two-channel approach with explicit treatment of
coupling of channels ^3\text{Z}+\Lambda+\Lambda and \alpha+\Xi. Diagonal
\Lambda\Lambda and coupling \Lambda\Lambda-\Xi N interactions are derived
within G-matrix procedure from Nijmegen meson-exchange models. Bond energy
\Delta B_{\Lambda\Lambda} in He exceeds significantly
that in H due to the channel coupling. Diagonal \Xi\alpha
attraction amplifies the effect, which is sensitive also to \Lambda-core
interaction. The difference of the \Delta B_{\Lambda\Lambda} values can be an
unambiguous signature of the \Lambda\Lambda-\Xi N coupling in \Lambda\Lambda
hypernuclei. However, improved knowledge of the hyperon-nucleus potentials is
needed for quantitative extraction of the coupling strength from future data on
the \Lambda\Lambda hypernuclear binding energies.Comment: 11 pages with 3 figures; Phys. Rev. C, accepte
Atomic Resonance and Scattering
Contains research objectives.Joint Services Electronics Programs (U. S. Army, U.S. Navy, and U.S. Air Force) under Contract DA 36-039-AMC-03200(E)Sloan Fund for Basic Research (M.I.T. Grant 95
Atomic Resonance and Scattering
Contains research objectives, summary of research and reports on three research projects.U. S. Navy (Office of Naval Research) under Contract N00014-67-A-0204-0006Joint Services Electronics Programs (U. S. Army, U.S. Navy, and U. S. Air Force) under Contract DA 28-043-AMC-02536(E
Mixing-induced CP violating sources for electroweak baryogenesis from a semiclassical approach
The effects of flavor mixing in electroweak baryogenesis is investigated in a
generalized semiclassical WKB approach. Through calculating the nonadiabatic
corrections to the particle currents it is shown that extra CP violation
sources arise from the off-diagonal part of the equation of motion of particles
moving inside the bubble wall. This type of mixing-induced source is of the
first order in derivative expansion of the Higgs condensate, but is oscillation
suppressed. The numerical importance of the mixing-induced source is discussed
in the Minimal Supersymmetric Standard Model and compared with the source term
induced by semiclassical force. It is found that in a large parameter space
where oscillation suppression is not strong enough, the mixing-induced source
can dominate over that from the semiclassical force.Comment: 19 pp, 2 figs, 1 table, some comments added, to appear in
Eur.Phys.J.
Atomic Resonance and Scattering
Contains report on one research project.Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 28-043-AMC-02536(E)Sloan Fund for Basic Research (M. I. T. Grant 170)U. S. Navy (Office of Naval Research) under Contract N00014-67-A-0204-000
Older cancer patients during the COVID-19 epidemic: Practice proposal of the international geriatric radiotherapy group
The coronavirus disease 19 (COVID-19) pandemic is unprecedented as it reached all countries in the world within a record short period of time. Even though COVID-19 infection may be just severe in any adults, older adults (65-year-old or older) may experience a higher mortality rate. Among those affected, cancer patients may have a worse outcome compared to the general population because of their depressed immune status. As the health resources of most countries are limited, clinicians may face painful decisions about which patients to save if they require artificial ventilation. Cancer patients, especially the older ones, may be denied supportive care because of their shorter life expectancy. Thus, special considerations should be taken to prevent infection of older cancer patients and to provide them with adequate social support during their cancer treatment. The following proposal was reached: (1) Education of health care providers about the special needs of older cancer patients and their risks of infection. (2) Special consideration such as surgical masks and separate scheduling should be made to protect them from being infected. (3) Social services such as patient navigators should be provided to ensure adequate medical supply, food, and daily transportation to cancer centers. (4) Close monitoring through phone calls, telecommunication to ensure social distancing and psychological support from patient family to prevent anxiety and depression. (5) Shorter course of radiotherapy by use of hypofractionation where possible to decrease the needs for daily transportation and exposure to infection. (6) Enrollment of older cancer patients in clinical trials for potential antiviral medications if infection does occur. (7) Home health care telemedicine may be an effective strategy for older cancer patients with COVID-19 infection to avoid hospital admission when health care resources become restricted. (8) For selected patients, immunotherapy and targeted therapy may become the systemic therapy of choice for older cancer patients and need to be tested in clinical trials
Structural, 57 Fe Mössbauer and XPS studies of mechanosynthesized nanocrystalline Nd0.33Eu0.67Fe1-xCrxO3 particles
We report on the structure and surface composition of Nd0.33Eu0.67Fe1-xCrxO3 (x = 0.0, 0.3, 0.5, 0.7, 0.9 and 1.0) nanoparticles (∼30 nm) mechanosynthesized at temperatures that are ∼ 470– 700 °C lower than those at which the pure and doped pristine materials conventionally form. XRD Rietveld and FT-IR analyses show that with increasing x the lattice parameters decrease and the bond lengths and angles vary in a way that reduces crystalline distortion. Whilst the majority of the Eu3+/Nd3+ and Fe3+/Cr3+ cations occupy the normal perovskite-related A- and B-sites, respectively, ∼ 5% of them exchange sites. 57Fe Mössbauer spectroscopy confirms the presence of these antisites and reveals a superparamagnetic behaviour at 298 K that enhances with increasing x. XPS measurement reveals a complex surface composition of the nanoparticles with traces of Eu2O3, Nd2O3, Cr2O3 and Fe2O3 as well as partial O2--deficiency
Adjuvant PD-1 and PD-L1 Inhibitors and Relapse-Free Survival in Cancer Patients: The MOUSEION-04 Study
Background: Adjuvant treatment has always been a cornerstone in the therapeutic approach of many cancers, considering its role in reducing the risk of relapse and, in some cases, increasing overall survival. Adjuvant immune checkpoint inhibitors have been tested in different malignancies. Methods: We performed a meta-analysis aimed to explore the impact of adjuvant PD-1 and PD-L1 inhibitors on relapse-free survival (RFS) in cancer patients enrolled in randomized controlled clinical trials. We retrieved all phase III trials published from 15 June 2008 to 15 May 2022, evaluating PD-1/PD-L1 inhibitors monotherapy as an adjuvant treatment by searching on EMBASE, Cochrane Library, and PubMed/ Medline, and international oncological meetings’ abstracts. The outcome of interest was RFS. We also performed subgroup analyses focused on age and gender. Results: Overall, 8 studies, involving more than 6000 patients, were included in the analysis. The pooled results highlighted that the use of adjuvant PD-1/PD-L1 inhibitors may reduce the risk of relapse compared to control treatments (hazard ratio, 0.72; 95% confidence intervals, 0.67–0.78). In addition, the subgroup analyses observed that this benefit was consistent in different patient populations, including male, female, younger, and older patients. Conclusions: Adjuvant anti-PD-1/PD-L1 treatment is associated with an increased RFS in the overall population and in subgroups divided according to age and gender
Faddeev calculations for the A=5,6 Lambda-Lambda hypernuclei
Faddev calculations are reported for Lambda-Lambda-5H, Lambda-Lambda-5He and
Lambda-Lambda-6He in terms of two Lambda hyperons plus the respective nuclear
clusters, using Lambda-Lambda central potentials considered in past non-Faddeev
calculations of Lambda-Lambda-6He. The convergence with respect to the
partial-wave expansion is studied, and comparison is made with some of these
Lambda-Lambda hypernuclear calculations. The Lambda-Lambda Xi-N mixing
effect is briefly discussed.Comment: submitted for publicatio
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