1,665 research outputs found
A database for the stocks and flows of sand and gravel
Increasing demand for sand and gravel globally is leading to social, environmental, and political issues that are becoming more widely recognised. Lack of data and poor accessibility of the few available data contribute to exacerbating these issues and impair evidence-based management efforts. This paper presents a database to store stocks and flows data for sand and gravel from different sources. The classification system underlying within it builds on the Universal Materials Information System (UMIS) nomenclature, which is used to construct hierarchical order in the data and in the same manner as the Yale Stocks and Flow Database (YSTAFDB), a common data format. To illustrate how the database is built and used, a case study using UK data is presented. The UK is chosen owing to relatively better access to data compared to other locations. Quantitative analyses of the data show the supply chain of these materials to be currently stable for the UK as indigenous extraction contributes 95.6% to UK sand and gravel production, with imports accounting for the rest of the inputs, of which 50% is reliant on only one nation
Investigating expectation and reward in human opioid addiction with [C-11]raclopride PET
Tunable magnetic exchange interactions in manganese-doped inverted core/shell ZnSe/CdSe nanocrystals
Magnetic doping of semiconductor nanostructures is actively pursued for
applications in magnetic memory and spin-based electronics. Central to these
efforts is a drive to control the interaction strength between carriers
(electrons and holes) and the embedded magnetic atoms. In this respect,
colloidal nanocrystal heterostructures provide great flexibility via
growth-controlled `engineering' of electron and hole wavefunctions within
individual nanocrystals. Here we demonstrate a widely tunable magnetic sp-d
exchange interaction between electron-hole excitations (excitons) and
paramagnetic manganese ions using `inverted' core-shell nanocrystals composed
of Mn-doped ZnSe cores overcoated with undoped shells of narrower-gap CdSe.
Magnetic circular dichroism studies reveal giant Zeeman spin splittings of the
band-edge exciton that, surprisingly, are tunable in both magnitude and sign.
Effective exciton g-factors are controllably tuned from -200 to +30 solely by
increasing the CdSe shell thickness, demonstrating that strong quantum
confinement and wavefunction engineering in heterostructured nanocrystal
materials can be utilized to manipulate carrier-Mn wavefunction overlap and the
sp-d exchange parameters themselves.Comment: To appear in Nature Materials; 18 pages, 4 figures + Supp. Inf
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Distribution of halon-1211 in the upper troposphere and lower stratosphere and the 1994 total bromine budget
Acquiring Tetanus After Hemorrhoid Banding and Other Gastrointestinal Procedures
Tetanus after hemorrhoidal banding is an extremely rare but serious complication of the procedure. We describe the second reported case of this complication and review the literature concerning tetanus after different gastrointestinal procedures. Although a rare complication, practicing physicians need to be aware of the clinical presentation of this deadly disease when encountered in at-risk patient populations. Such cases also reemphasize the importance of primary tetanus immunization and follow-up boosters for all vulnerable patients
Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease
<div><p>Background</p><p>In humans, acromegaly due to a pituitary somatotrophic adenoma is a recognized cause of increased left ventricular (LV) mass. Acromegalic cardiomyopathy is incompletely understood, and represents a major cause of morbidity and mortality. We describe the clinical, echocardiographic and histopathologic features of naturally occurring feline acromegalic cardiomyopathy, an emerging disease among domestic cats.</p><p>Methods</p><p>Cats with confirmed hypersomatotropism (IGF-1>1000ng/ml and pituitary mass; n = 67) were prospectively recruited, as were two control groups: diabetics (IGF-1<800ng/ml; n = 24) and healthy cats without known endocrinopathy or cardiovascular disease (n = 16). Echocardiography was performed in all cases, including after hypersomatotropism treatment where applicable. Additionally, tissue samples from deceased cats with hypersomatotropism, hypertrophic cardiomyopathy and age-matched controls (n = 21 each) were collected and systematically histopathologically reviewed and compared.</p><p>Results</p><p>By echocardiography, cats with hypersomatotropism had a greater maximum LV wall thickness (6.5mm, 4.1–10.1mm) than diabetic (5.9mm, 4.2–9.1mm; Mann Whitney, p<0.001) or control cats (5.2mm, 4.1–6.5mm; Mann Whitney, p<0.001). Left atrial diameter was also greater in cats with hypersomatotropism (16.6mm, 13.0–29.5mm) than in diabetic (15.4mm, 11.2–20.3mm; Mann Whitney, p<0.001) and control cats (14.0mm, 12.6–17.4mm; Mann Whitney, p<0.001). After hypophysectomy and normalization of IGF-1 concentration (n = 20), echocardiographic changes proved mostly reversible. As in humans, histopathology of the feline acromegalic heart was dominated by myocyte hypertrophy with interstitial fibrosis and minimal myofiber disarray.</p><p>Conclusions</p><p>These results demonstrate cats could be considered a naturally occurring model of acromegalic cardiomyopathy, and as such help elucidate mechanisms driving cardiovascular remodeling in this disease.</p></div
Derivation and validation of the NAFLD Cirrhosis Score (NCS) to distinguish bridging fibrosis from cirrhosis
On the role of different Skyrme forces and surface corrections in exotic cluster-decay
We present cluster decay studies of Ni formed in heavy-ion
collisions using different Skyrme forces. Our study reveals that different
Skyrme forces do not alter the transfer structure of fractional yields
significantly. The cluster decay half-lives of different clusters lies within
\pm 10% for PCM and \pm 15% for UFM.Comment: 13 pages,6 figures and 1 table; in press Pramana Journal of Physics
(2010
Biodiversity Loss and the Taxonomic Bottleneck: Emerging Biodiversity Science
Human domination of the Earth has resulted in dramatic changes to global and local patterns of biodiversity. Biodiversity is critical to human sustainability because it drives the ecosystem services that provide the core of our life-support system. As we, the human species, are the primary factor leading to the decline in biodiversity, we need detailed information about the biodiversity and species composition of specific locations in order to understand how different species contribute to ecosystem services and how humans can sustainably conserve and manage biodiversity. Taxonomy and ecology, two fundamental sciences that generate the knowledge about biodiversity, are associated with a number of limitations that prevent them from providing the information needed to fully understand the relevance of biodiversity in its entirety for human sustainability: (1) biodiversity conservation strategies that tend to be overly focused on research and policy on a global scale with little impact on local biodiversity; (2) the small knowledge base of extant global biodiversity; (3) a lack of much-needed site-specific data on the species composition of communities in human-dominated landscapes, which hinders ecosystem management and biodiversity conservation; (4) biodiversity studies with a lack of taxonomic precision; (5) a lack of taxonomic expertise and trained taxonomists; (6) a taxonomic bottleneck in biodiversity inventory and assessment; and (7) neglect of taxonomic resources and a lack of taxonomic service infrastructure for biodiversity science. These limitations are directly related to contemporary trends in research, conservation strategies, environmental stewardship, environmental education, sustainable development, and local site-specific conservation. Today’s biological knowledge is built on the known global biodiversity, which represents barely 20% of what is currently extant (commonly accepted estimate of 10 million species) on planet Earth. Much remains unexplored and unknown, particularly in hotspots regions of Africa, South Eastern Asia, and South and Central America, including many developing or underdeveloped countries, where localized biodiversity is scarcely studied or described. ‘‘Backyard biodiversity’’, defined as local biodiversity near human habitation, refers to the natural resources and capital for ecosystem services at the grassroots level, which urgently needs to be explored, documented, and conserved as it is the backbone of sustainable economic development in these countries. Beginning with early identification and documentation of local flora and fauna, taxonomy has documented global biodiversity and natural history based on the collection of ‘‘backyard biodiversity’’ specimens worldwide. However, this branch of science suffered a continuous decline in the latter half of the twentieth century, and has now reached a point of potential demise. At present there are very few professional taxonomists and trained local parataxonomists worldwide, while the need for, and demands on, taxonomic services by conservation and resource management communities are rapidly increasing. Systematic collections, the material basis of biodiversity information, have been neglected and abandoned, particularly at institutions of higher learning. Considering the rapid increase in the human population and urbanization, human sustainability requires new conceptual and practical approaches to refocusing and energizing the study of the biodiversity that is the core of natural resources for sustainable development and biotic capital for sustaining our life-support system. In this paper we aim to document and extrapolate the essence of biodiversity, discuss the state and nature of taxonomic demise, the trends of recent biodiversity studies, and suggest reasonable approaches to a biodiversity science to facilitate the expansion of global biodiversity knowledge and to create useful data on backyard biodiversity worldwide towards human sustainability
Designing an information system for updating land records in Bangladesh: action design ethnographic research (ADER)
Open Access. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.This article has been made available through the Brunel Open Access Publishing Fund.Information Systems (IS) has developed through adapting, generating and applying diverse methodologies, methods, and techniques from reference disciplines. Further, Action Design Research (ADR) has recently developed as a broad research method that focuses on designing and redesigning IT and IS in organizational contexts. This paper reflects on applying ADR in a complex organizational context in a developing country. It shows that ADR requires additional lens for designing IS in such a complex organizational context. Through conducting ADR, it is seen that an ethnographic framework has potential complementarities for understanding complex contexts thereby enhancing the ADR processes. This paper argues that conducting ADR with an ethnographic approach enhances design of IS and organizational contexts. Finally, this paper aims presents a broader methodological framework, Action Design Ethnographic Research (ADER), for designing artefacts as well as IS. This is illustrated through the case of a land records updating service in Bangladesh
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