13,710 research outputs found
Detection of Mycobacterium tuberculosis and Drug Resistance: Opportunies and Challenges in Morocco
365 Things I Learned in My Kitchen
Hello! I\u27m Katie, and I\u27ve been living in Belgium for about ten years. Belgian food is delicious, but sometimes you just need something that reminds you of home. Finding this can pose a problem in Belgium, so I often make this from scratch. I don\u27t grow our own or milk cows or anything like that, but I do cook with food that my grandmother would recognise. I also love Asian and Indian food and I often make this too (it’s the only way to guarantee you get the spiciness you need!). I try to cook low-fat, although some things I just refuse to meddle with (such as sticky toffee pudding)
CASCH: a tool for computer-aided scheduling
A software tool called Computer-Aided Scheduling (CASCH) for parallel processing on distributed-memory multiprocessors in a complete parallel programming environment is presented. A compiler automatically converts sequential applications into parallel codes to perform program parallelization. The parallel code that executes on a target machine is optimized by CASCH through proper scheduling and mapping.published_or_final_versio
COVID-19: Causes of anxiety and wellbeing support needs of healthcare professionals in the UK: A cross-sectional survey.
BACKGROUND: COVID-19 has caused acute changes in healthcare delivery; this may impact mental health and wellbeing needs of healthcare professionals (HCPs). AIMS: We aimed to identify the causes of anxiety in HCPs during the COVID-19 pandemic, to assess whether HCPs felt they had adequate mental health and wellbeing support and to identify their unmet support needs. METHOD: We used a web-based survey utilising an online tool circulated to UK HCPs over 5 weeks. Self-perceived anxiety levels prior to and during the COVID-19 pandemic were measured on a 10-point Likert-type rating scale. RESULTS: The survey was completed by 558 HCPs. During the pandemic, self-perceived anxiety scores significantly increased from a median of 2 to 7 (paired Wilcoxon signed-rank test; p<0.001). The main reasons were concerns about exposure to SARS-CoV-2 and lack of personal protective equipment. Other wide-ranging reasons were identified. Only 41% of respondents felt there was adequate support. Thematic analysis of what support HCPs wanted identified 13 wide-ranging themes; including effective leadership and peer support. CONCLUSION: Anxiety levels in HCPs significantly increased during the COVID-19 pandemic and the main causes were identified. Many HCPs felt there was inadequate support and identified what support they needed. Implementing effective strategies to support HCPs' unmet wellbeing needs are required as a matter of urgency
Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong
This study assessed the changes in serotype distribution and antibiotic resistance of Streptococcus pneumoniae isolates in children before and after introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in Hong Kong. Nasopharyngeal specimens were collected from 1978 and 2211 children (ages, 2 to 6 years) attending day care centers or kindergartens in period 1 (1999-2000) and period 2 (2009-2010), respectively. Carriage of PCV7 serotypes decreased from 12.8% to 8.6% (P < 0.01). The relative contribution of PCV7 serotypes 14 and 18C had decreased, whereas that for non-PCV7 serotypes 19A, 6A, 6C, 23A, and 15B had increased. In period 2, PCV7 penetration rate (at least 1 dose) for children aged 2, 3, 4, and 5 years was 43%, 35.7%, 26.7%, and 20.4%, respectively. In multivariate analysis, PCV7 use was the only independent variable associated with fewer PCV7 serotype carriages (odds ratio 0.5; P = 0.001). In period 2, high rates of dual penicillin/erythromycin nonsusceptibility were found in serotypes 6B (77.3%), 14 (100%), 19F (100%), 23F (78%), 19A (75%), 6A (87.8%), 6C (59.3%), and 23A (78.9%).postprin
Cd36 Is Expressed In A Defined Subpopulation Of Neurons In The Olfactory Epithelium
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)The sensory neurons in the olfactory epithelium (OSNs) are equipped with a large repertoire of olfactory receptors and the associated signal transduction machinery. In addition to the canonical OSNs, which express odorant receptors (ORs), the epithelium contains specialized subpopulations of sensory neurons that can detect specific information from environmental cues and relay it to relevant neuronal circuitries. Here we describe a subpopulation of mature OSNs in the main olfactory epithelium (MOE) which expresses CD36, a multifunctional receptor involved in a series of biological processes, including sensory perception of lipid ligands. The Cd36 expressing neurons coexpress markers of mature OSNs and are dispersed throughout the MOE. Unlike several ORs analyzed in our study, we found frequent coexpression of the OR Olfr287 in these neurons, suggesting that only a specific set of ORs may be coexpressed with CD36 in OSNs. We also show that CD36 is expressed in the cilia of OSNs, indicating a possible role in odorant detection. CD36-deficient mice display no signs of gross changes in the organization of the olfactory epithelium, but show impaired preference for a lipid mixture odor. Our results show that CD36-expressing neurons represent a distinct population of OSNs, which may have specific functions in olfaction.6Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [FAPESP: 2007/53732-8]Conselho Nacional de Desenvolvimento Cientifico e Tecnologico [CNPq 484869/2012-4]FAPESP [FAPESP11/51604-8]Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP
BENTONITE/CHITOSAN BIOCOMPOSITE AS AN ADSORBENT FOR HEXAVALENT CHROMIUM FROM AQUEOUS SOLUTIONS
The present work focuses on the study of the application of abundant and less expensive materials such as chitosan and bentonite/chitosan biocomposite in the removal of hexavalent chromium. Spectroscopic analysis like techniques FTIR, XRD and BET have been used to characterize the adsorbents. The data indicate that the adsorption of chromium proceeds kinetically according to a pseudo-second order model on both samples and the apparent activation energy (Ea) have been measured to be 22.9 kJ.mol−1 and 84.4 kJ.mol−1 for chitosan and 5%Bt/CS, respectively. The adsorption isotherm experiments show that the adsorption capacity depends on the studied chromium adsorption temperature. It has been found that the data could be well described by the Langmuir as well as the Freundlich models. Thermodynamic parameters (i.e., change in the free energy (DG°), the enthalpy (DH°), and the entropy (DS°) have been also, evaluated
Mannose binding lectin (MBL) codon 54 gene polymorphism and susceptibility to infection in patients with systemic lupus erythematosus (SLE)
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Effect of the immunosuppressant FK506 on glucose-induced insulin secretion from adult rat islets of langerhans
Incidence of anorexia nervosa and the prescribing of psychotropic medications from UK Primary Care, 1996-2016: A retrospective database study
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