146 research outputs found

    A lyceum catechist of a provincial town in the conditions of the education system reformation in the Russian Empire of the 19<sup>th</sup> - early 20<sup>th</sup> centuries: Prosopographic reconstruction

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    © 2015 by the author(s). The importance of the research is caused by the significance of institutional history issues in modern history research, i.e. functioning of educational systems as a special field of interaction of state and society, various public institutions, science, an individual and generations (teachers and students). The purpose of the article is to determine the position of the lyceum catechist in a secular educational environment based on research of a particular era (19th - early 20th centuries) and a specific region (Kazan as a typical provincial center of the Russian Empire). The main methodology of the research has become the prosopography method used to create the collective biographies by identifying a specific group of persons related to a common field and interests, representing a corporate community (in this case - the Orthodox Church), implemented by the responses to the same questions. In the research, the authors obtained results showing a unique position of a lyceum catechist in the Russian Empire of specified period who belonged simultaneously to two corporations - the clergy of the Orthodox Church and members of the educational community of secular secondary education. The requirements of each of these corporations to be met by their members often came into conflict between particular individuals. These circumstances have contributed to the deepening crisis of religious education in secular educational environment of the Russian Empire. The results presented in the article may be useful for the studies within the institutional history of education and the church, as well as for modern Russian discussions about the place of religion in a secular educational environment

    The influence of forms of insurance coverage organization on population's life quality

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    © 2014, Mediterranean Center of Social and Educational Research. All rights reserved. Social insurance is essential for the development of population's quality of life because it fulfils social functions such as low- income citizens support; and economic functions such as the renewal of human resources; the development of the voluntary insurance market due to the increase in effective demand. For historical reasons, there are different types of correlation between compulsory social and voluntary insurance. These types depend on the stage of the development of national economies of countries, as well as from the historically formed principles of social security. Each type has its own purposes, negative and positive sides. Furthermore, we should not forget the specific features of each national economy

    Concorrência tributária entre regiões da Rússia e seus indicadores

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    The article focuses on approaches to assessing the competitive advantages of regions of Russia in the area of taxation, the main approaches to the definition of tax competition at the present stage used in the scientific literature, are considered; emphasis on the influence of internal tax competition on social and economic development of the regions; the possibilities of using a number of quantitative and qualitative indicators to assess the competitive advantages of the regions in the area of taxation are summarized; ranking of the regions of Russia by using tax authorities to provide tax benefits of corporate income tax paid to the budget of the Russian Federation constituent, was performed; the conclusion about the relationship of investment activity and the availability of competitive advantages in the area of taxation was made; the development problems of the regional competitive advantages in the area of taxation and prospects for their solution are described.El artículo se centra en los enfoques para evaluar las ventajas competitivas de las regiones de Rusia en el área de la tributación, se consideran los principales enfoques para la definición de competencia fiscal en la etapa actual utilizados en la literatura científica; énfasis en la influencia de la competencia fiscal interna sobre el desarrollo social y económico de las regiones; se resumen las posibilidades de utilizar una serie de indicadores cuantitativos y cualitativos para evaluar las ventajas competitivas de las regiones en el área de la tributación; clasificación de las regiones de Rusia mediante el uso de las autoridades fiscales para proporcionar los beneficios fiscales del impuesto sobre la renta corporativo pagado al presupuesto del constituyente de la Federación de Rusia; se llegó a la conclusión sobre la relación de la actividad inversora y la disponibilidad de ventajas competitivas en el área de tributación; se describen los problemas de desarrollo de las ventajas competitivas regionales en el área de impuestos y las perspectivas para su solución.&nbsp;O artigo enfoca as abordagens para avaliar as vantagens competitivas das regiões russas na área de tributação, considerando as principais abordagens para a definição de concorrência tributária no atual estágio utilizado na literatura científica; ênfase na influência da concorrência fiscal interna no&nbsp;desenvolvimento social e econômico das regiões; as possibilidades de utilizar uma série de indicadores&nbsp;quantitativos e qualitativos para avaliar as vantagens competitivas das regiões na área de tributação são&nbsp;resumidas; classificação das regiões da Rússia, usando as autoridades fiscais para fornecer os benefíciosfiscais do imposto de renda corporativo pago ao orçamento do constituinte da Federação Russa; chegouse&nbsp;à conclusão sobre a relação entre a atividade de investimento e a disponibilidade de vantagens&nbsp;competitivas na área de tributação; São descritos os problemas de desenvolvimento de vantagenscompetitivas regionais na área tributária e as perspectivas de sua solução

    Aspectos gerais de estudos regionais e tecnologias de facilitação no estudo de criações de pintores renomados e escritores destacados

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    The article deals with landscapes of painter I.I. Shishkin (1832–1898) and XIX century writer, poet and journalist D.I. Stakheev (1840–1918) as part of general regional studies. The research is based on the possibility of correlation of the main and regional educational components in school and college literary regional studies; on the analytical technologies based on comparative contextual analysis of literary works and canvases. Among the most productive methods there is an analysis of cross-cutting subject matters, motives and images. Literary works of D.I. Stakheev and paintings of I.I. Shishkin are viewed as part of their life, work and friendly interaction. Taking into account the fact that these cultural figures lived and worked in Yelabuga we may include historical, biographical, literary and analytical records into the so-called regional component of literary and general cultural education content. However, a special interest for us is in the possibility of combining two planes: local literature and painting of a particular region and “serious” literature and “high” art of all-Russian and even global scale. Among other things the article presents facilitation technology effectively ensuring high level of research projects implementation due to three components: speed, creativity and efficiency. Detailed consideration is given to “World Café” and “Trade Show” models which are recommended for use both for study of the creative workers life and work and for handling information about their work.El artículo trata sobre los paisajes del pintor I.I. Shishkin (1832–1898) y escritor, poeta y periodista del siglo XIX D.I. Stakheev (1840–1918) como parte de estudios regionales generales. La investigación se basa en la posibilidad de correlación de los componentes educativos principales y regionales en los estudios regionales literarios escolares y universitarios; En las tecnologías analíticas basadas en análisis comparativos contextuales de obras literarias y lienzos. Entre los métodos más productivos se encuentra un análisis de temas, motivos e imágenes transversales. Obras literarias de D.I. Stakheev y pinturas de I.I. Los shishkin son vistos como parte de su vida, trabajo e interacción amistosa. Teniendo en cuenta el hecho de que estas figuras culturales vivieron y trabajaron en Yelabuga, podemos incluir registros históricos, biográficos, literarios y analíticos en el llamado componente regional del contenido de la educación literaria y cultural en general. Sin embargo, un interés especial para nosotros radica en la posibilidad de combinar dos planos: la literatura local y la pintura de una región en particular y la literatura "seria" y el arte "alto" de toda escala rusa e incluso global. Entre otras cosas, el artículo presenta tecnología de facilitación que garantiza un alto nivel de implementación de proyectos de investigación debido a tres componentes: velocidad, creatividad y eficiencia. Se da una consideración detallada a los modelos "World Café" y "Trade Show", que se recomiendan tanto para el estudio de la vida y el trabajo de los trabajadores&nbsp;creativos como para el manejo de la información sobre su trabajo.O artigo trata das paisagens do pintor I.I. Shishkin (1832–1898) e escritor, poeta e jornalista do século XIX D.I. Stakheev (1840-1918) como parte de estudos regionais gerais. A pesquisa é baseada na possibilidade de correlação dos componentes educacionais principais e regionais em estudos regionais literários escolares e universitários; sobre as tecnologias analíticas baseadas em análise comparativa contextual de obras literárias e telas. Entre os métodos mais produtivos, há uma análise de assuntos transversais, motivos e imagens. Trabalhos literários de D.I. Stakheev e pinturas de I.I. Shishkin são vistos como parte de sua vida, trabalho e interação amigável. Levando em conta o fato de que essas figuras culturais viveram e trabalharam em Yelabuga, podemos incluir registros históricos, biográficos, literários e analíticos no chamado componente regional de conteúdo de educação cultural literária e geral. No entanto, um interesse especial para nós é a possibilidade de combinar dois planos: literatura local e pintura de uma região específica e literatura “séria” e arte “alta” de escala totalmente russa e até global. Entre outras coisas, o artigo apresenta tecnologia de facilitação que garante efetivamente alto nível de implementação de projetos de pesquisa devido a três componentes: velocidade, criatividade e eficiência. Consideração detalhada é dada aos modelos “World Café” e “Trade Show”, que são recomendados para uso tanto para o estudo da vida e do trabalho dos trabalhadores criativos quanto para o manuseio de informações sobre seu trabalho

    Acid Sensitive Ion Channels as Target of Hydrogen Sulfide in Rat Trigeminal Neurons

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    © 2016, Springer Science+Business Media New York.Hydrogen sulfide (H2S), an endogenous gasotransmitter, was proposed to act as a signaling molecule in a wide variety of pathophysiological processes including inflammation and nociception. Acid-sensing ion channels (ASICs) are voltage-insensitive, proton-gated cation channels activated by extracellular acidosis, and are involved in various pathologies of the nervous system including ischemia, stroke, and migraine. In this study, the effect of the H2S donor-sodium hydrogen sulfide (NaHS) on the firing of trigeminal (TG) nerve was explored using suction electrode recordings in peripheral branches of the TG nerve in isolated rat meninges, and patch clamp recordings of ASIC currents in isolated TG neurons. NaHS (100 μM) increased the action potential frequency of TG nerve and bath application of NaHS increased the amplitude of ASIC currents triggered by focal application of low pH solution on isolated TG neurons. We propose that activation of ASICs by H2S during chronic inflammation process contributes to the increased excitability of the TG system and may be implicated in the generation of nociceptive firing underlying migraine pain

    Case of the death due to drowning

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    Аналіз казуїстичних випадків смерті свідчить не лише про труднощі та особливості судово-медичних експертиз, але іноді не співпадає з танатогенезом від різних чинників смерті у воді, що може настати не лише від утоплення, але й від раптової зупинки серця, черепно-мозкової травми. Деякі автори виділяють рефлекторний тип утоплення пов’язаний з різким перепадом температур тіла людини і води

    Homocysteine augments BK channel activity and decreases exocytosis of secretory granules in rat GH3 cells

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    © 2016 Federation of European Biochemical SocietiesIn this study, we investigated the effects of L-homocysteine (Hcy) on maxi calcium-activated potassium (BK) channels and on exocytosis of secretory granules in GH3 rat pituitary-derived cells. A major finding of our study indicates that short-term application of Hcy increased the open probability of oxidized BK channels in inside-out recordings. Whole-cell recordings show that extracellular Hcy also augmented BK currents during long-term application. Furthermore, Hcy decreased the exocytosis of secretory granules. This decrease was partially prevented by the BK channel inhibitor paxilline and fully prevented by N-acetylcysteine, a reactive oxygen species scavenger. Taken together, our data show that elevation of cellular Hcy level induces oxidative stress, increases BK channel activity, and decreases exocytosis of secretory granules. These findings may provide insight into some of the developmental impairments and neurotoxicity associated with Hyperhomocysteinemia (HHcy), a disease arising due to abnormally elevated levels of Hcy in the plasma
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