Systematic review of brucellosis in the Middle East: disease frequency in ruminants and humans and risk factors for human infection

This paper considers the problem of finding global states incoming to a specified global state in a Boolean network, which may be useful for pre-processing of finding a sequence of control actions for a Boolean network and for identifying the basin of attraction for a given attractor, We show that this problem is NP-hard in general along with related theoretical results, On the other hand, we present algorithms that are much faster than the naive exhaustive search-based algorithm. ©2007 IEEE.link_to_subscribed_fulltex

Mechanisms of Renal Disease in β-Thalassemia

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Thalassemia and Venous Thromboembolism

Although the life expectancy of thalassemia patients has markedly improved over the last few decades, patients still suffer from many complications of this congenital disease. The presence of a high incidence of thromboembolic events, mainly in thalassemia intermedia, has led to the identification of a hypercoagulable state in these patients. In this review, the molecular and cellular mechanisms leading to hypercoagulability in thalassemia are highlighted, with a special focus on thalassemia intermedia being the group with the highest incidence of thrombotic events as compared to other types of thalassemia. Clinical experience and available clues on optimal management are also discussed

Burkitt's lymphoma of the colon and bronchi: three case reports

This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens

Thalassaemia Intermedia: an Update

Our understanding of the molecular and pathophysiological mechanisms underlying the disease process in patients with thalassaemia intermedia (TI) has substantially increased over the past decade. TI encompasses a wide clinical spectrum of beta-thalassaemia phenotypes. Some TI patients are asymptomatic until adult life, whereas others are symptomatic from as young as 2 years of age. A number of clinical complications commonly associated with TI are rarely seen in thalassaemia major, including extramedullary hematopoiesis, leg ulcers, gallstones, thrombosis and pulmonary hypertension. There are a number of options currently available for managing patients with TI, including transfusion therapy, iron chelation therapy, modulation of foetal haemoglobin production and haematopoietic stem cell transplantation. However, at present, there are no clear guidelines for an orchestrated optimal treatment plan

The dynamics and determinants of Kuwait's long-run economic growth

This paper develops a quarterly macro-econometric model for the Kuwaiti economy estimated over the period 1979Q2-2013Q1, allowing us to investigate the long-run role of oil income in the development of Kuwait as well as the direct effects of oil revenue, foreign output, and equity price shocks on real output. More specifically, we examine to what extent Kuwaiti real output in the long run is shaped by oil revenue through their impact on capital accumulation, and technological transfers through foreign output. Using the same modelling strategy we also explore the role of oil income in terms of long-run private and public sector output growth (separately). The estimates suggest that real domestic output in the long run is influenced by oil revenues and foreign output (a proxy for technological progress), and technological growth in Kuwait is on a par with the rest of the world. Furthermore, while we show that both oil revenues and foreign output drive growth in the public sector, it seems that technological progress is the main (and only) driver for private sector real growth. Finally, our results show that oil revenue and global equity market shocks have a large and significant long-run impact on Kuwait's real output and public sector GDP. In comparison, the effects of the foreign output shock is muted

Coagulopathy in Beta-Thalassemia: Current Understanding and Future Perspectives

As the life expectancy of β-thalassemia patients has markedly improved over the last decade, several new complications are being recognized. The presence of a high incidence of thromboembolic events, mainly in thalassemia intermedia patients, has led to the identification of a hypercoagulable state in thalassemia. In this review, the molecular and cellular mechanisms leading to hypercoagulability in thalassemia are highlighted, and the current clinical experience is summarized. Recommendations for thrombosis prophylaxis are also discussed

Aspirin Resistance

The development of adverse cardiovascular events despite aspirin use has established an interest in a possible resistance to the drug. Several definitions have been set and various laboratory testing modalities are available. This has led to a wide range of prevalence reports in different clinical entities. The etiologic mechanism has been related to clinical, genetic, and other miscellaneous factors. The clinical implications of this phenomenon are significant and warrant concern. Management strategies are currently limited to dosing alteration and introduction of other anitplatelet agents. However, these measures have not met the expected efficacy or safety

Institutional Ownerships and Market Performance

This study examines the effects of institutional ownerships on market performance using a panel data from companies that are listed on Bursa Malaysia during the period of 2000 to 2009, this study uses Generalized Least Square (GLS) method. Results of GLS show that among seven Government-Linked Investment Companies (GLICs), only Permodalan Nasional Berhad (PNB) and Lembaga Tabung Angkatan Tentera (LTAT) have positive and significant impact on market performance. In addition, foreign and family ownerships also give positive impact on market performance. In contrast, the impacts of other five GLICs, state, domestic, board ownerships are not related to market performance. This study is one of first effort to examine each GLIC in Malaysian market. So far the previous studies have been done focusing GLICs as whole. The implications of this study will be for the policy maker and investors to make better decisions. DOI: 10.5901/mjss.2015.v6n4s3p57