41,287 research outputs found

    Thermal and structural modeling of superinsulation

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    Model permits direct physical measurement of the thermal response of critical components of space telescopes, thus providing flexibility for systems studies and design changes

    Pattern Formation by Boundary Forcing in Convectively Unstable, Oscillatory Media With and Without Differential Transport

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    Motivated by recent experiments and models of biological segmentation, we analyze the exicitation of pattern-forming instabilities of convectively unstable reaction-diffusion-advection (RDA) systems, occuring by means of constant or periodic forcing at the upstream boundary. Such boundary-controlled pattern selection is a generalization of the flow-distributed oscillation (FDO) mechanism that can include Turing or differential flow instability (DIFI) modes. Our goal is to clarify the relationships among these mechanisms in the general case where there is differential flow as well as differential diffusion. We do so by analyzing the dispersion relation for linear perturbations and showing how its solutions are affected by differential transport. We find a close relationship between DIFI and FDO, while the Turing mechanism gives rise to a distinct set of unstable modes. Finally, we illustrate the relevance of the dispersion relations using nonlinear simulations and we discuss the experimental implications of our results.Comment: Revised version with added content (new section and figures added), changes to wording and organizatio

    The timing of maternal depressive symptoms and child cognitive development: a longitudinal study.

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    Background: Maternal depression is known to be associated with impairments in child cognitive development, although the effect of timing of exposure to maternal depression is unclear. Methods: Data collected for the Avon Longitudinal Study of Parents and Children, a longitudinal study beginning in pregnancy, included self-report measures of maternal depression the Edinburgh Postnatal Depression Scale, completed on 6 occasions up to 3 years of age, and IQ of the index child (WISC) measured at aged 8 years. We used these data to assign women to 8 groups according to whether depression occurred in the antenatal, postnatal, preschool period, any combination of these times, or not at all. We compared a model comprising all patterns of depression (saturated model) with models nested within this to test whether there is a relationship between depression and child cognitive development and, if so, whether there is a sensitive period. We then investigated the relationship with child IQ for each model, following adjustment for confounders. Results: Six thousand seven hundred and thirty-five of 13,615 children from singleton births (49.5%, of eligible core sample) attended a research clinic at 8 years and completed a WISC with a score ā‰„ 70. A total of 5,029 mothers of these children had completed mood assessments over the 3 time periods. In unadjusted analyses, all three sensitive period models were as good as the saturated model, as was an accumulation model. Of the sensitive period models, only that for antenatal exposure was a consistently better fit than the accumulation model. After multiple imputation for missing data (to n = 6,735), there was no effect of postnatal depression on child IQ independent of depression at other times [-0.19 IQ points, 95% confidence interval (CI) -1.5 to 1.1 points]. There was an effect of antenatal depression (-3.19 IQ points, 95% CI: -4.33 to -2.06) which attenuated following adjustment (-0.64 IQ points, 95% CI: -1.68 to 0.40). Conclusions: The postnatal period is not a sensitive one for the effect of maternal depression on child cognitive development. Ā© 2011 The Authors. Journal of Child Psychology and Psychiatry

    Mapping the Outer Edge of the Young Stellar Cluster in the Galactic Center

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    We present new near-infrared spectroscopic observations of the outer edges of the young stellar cluster around the supermassive black hole at the Galactic center. The observations show a break in the surface-density profile of young stars at approximately 13 arcsec (0.52 pc). These observations spectroscopically confirm previous suggestions of a break based on photometry. Using Gemini North's Near-Infrared Integral Field Spectrometer (NIFS) we are able to detect and separate early- and late-type stars with a 75% completeness at Ks = 15.5. We sample a region with radii between 7" to 23" (0.28 pc to 0.92 pc) from Sgr A*, and present new spectral classifications of 144 stars brighter than Ks = 15.5, where 140 stars are late-type (> 1 Gyr) and only four stars are early-type (young, 4-6 Myr). A broken power-law fit of the early-type surface-density matches well with our data and previously published values. The projected surface-density of late-type stars is also measured and found to be consistent with previous results. We find that the observed early-type surface-density profile is inconsistent with the theory of the young stars originating from a tightly bound infalling cluster, as no significant trail of young stars is found at radii above 13". We also note that either a simple disk instability criterion or a cloud-cloud collision could explain the location of the outer edge, though we lack information to make conclusive remarks on either alternative. If this break in surface-density represents an edge to the young stellar cluster it would set an important scale for the most recent episode of star formation at the Galactic center.Comment: 17 pages, 11 figures, 3 tables, ApJ accepte

    Perceptual adaptation by normally hearing listeners to a simulated "hole" in hearing

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    Simulations of cochlear implants have demonstrated that the deleterious effects of a frequency misalignment between analysis bands and characteristic frequencies at basally shifted simulated electrode locations are significantly reduced with training. However, a distortion of frequency-to-place mapping may also arise due to a region of dysfunctional neurons that creates a "hole" in the tonotopic representation. This study simulated a 10 mm hole in the mid-frequency region. Noise-band processors were created with six output bands (three apical and three basal to the hole). The spectral information that would have been represented in the hole was either dropped or reassigned to bands on either side. Such reassignment preserves information but warps the place code, which may in itself impair performance. Normally hearing subjects received three hours of training in two reassignment conditions. Speech recognition improved considerably with training. Scores were much lower in a baseline (untrained) condition where information from the hole region was dropped. A second group of subjects trained in this dropped condition did show some improvement; however, scores after training were significantly lower than in the reassignment conditions. These results are consistent with the view that speech processors should present the most informative frequency range irrespective of frequency misalignment. 0 2006 Acoustical Society of America

    Brief of Amici Curiae Erika R. George and Kali N. Murray in Support of the Association for Molecular Pathology, et al

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    Amicus ("friend of the court") brief written by Erika George and Kali Murray in support of plaintiffs-appellees, Association for Molecular Pathology, et al (No. 2010-1406)
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