Dynamic clustering in active colloidal suspensions with chemical signaling

In this paper, we explore experimentally the phase behavior of a dense active suspension of self- propelled colloids. In addition to a solid-like and a gas-like phase observed for high and low densities, a novel cluster phase is reported at intermediate densities. This takes the form of a stationary assembly of dense aggregates, with an average size which grows with activity as a linear function of the self-propelling velocity. While different possible scenarii can be considered to account for these observations - such as a generic velocity weakening instability recently put forward -, we show that the experimental results are reproduced by a chemotactic aggregation mechanism, originally introduced to account for bacterial aggregation, and accounting here for diffusiophoretic chemical interaction between colloidal swimmers.Comment: supplementary video :http:// www-lpmcn.univ-lyon1.fr/~lbocquet/Movie-Theurkauff-SI.av

Matrix partitioning and EOF/principal component analysis of Antarctic Sea ice brightness temperatures

A field of measured anomalies of some physical variable relative to their time averages, is partitioned in either the space domain or the time domain. Eigenvectors and corresponding principal components of the smaller dimensioned covariance matrices associated with the partitioned data sets are calculated independently, then joined to approximate the eigenstructure of the larger covariance matrix associated with the unpartitioned data set. The accuracy of the approximation (fraction of the total variance in the field) and the magnitudes of the largest eigenvalues from the partitioned covariance matrices together determine the number of local EOF's and principal components to be joined by any particular level. The space-time distribution of Nimbus-5 ESMR sea ice measurement is analyzed

Enzyme kinetics for a two-step enzymic reaction with comparable initial enzyme-substrate ratios

We extend the validity of the quasi-steady state assumption for a model double intermediate enzyme-substrate reaction to include the case where the ratio of initial enzyme to substrate concentration is not necessarily small. Simple analytical solutions are obtained when the reaction rates and the initial substrate concentration satisfy a certain condition. These analytical solutions compare favourably with numerical solutions of the full system of differential equations describing the reaction. Experimental methods are suggested which might permit the application of the quasi-steady state assumption to reactions where it may not have been obviously applicable before

Intensity mapping cross-correlations II: HI halo models including shot noise

HI intensity mapping data traces the large-scale structure matter distribution using the integrated emission of neutral hydrogen gas (HI). The cross-correlation of the intensity maps with optical galaxy surveys can mitigate foreground and systematic effects, but has been shown to significantly depend on galaxy evolution parameters of the HI and the optical sample. Previously, we have shown that the shot noise of the cross-correlation scales with the HI content of the optical samples, such that the shot noise estimation infers the average HI masses of these samples. In this article, we present an adaptive framework for the cross-correlation of HI intensity maps with galaxy samples using our implementation of the halo model formalism (Murray et al 2018, in prep) which utilises the halo occupation distribution of galaxies to predict their power spectra. We compare two HI population models, tracing the spatial halo and the galaxy distribution respectively, and present their auto- and cross-power spectra with an associated galaxy sample. We find that the choice of the HI model and the distribution of the HI within the galaxy sample have minor significance for the shape of the auto- and cross-correlations, but highly impact the measured shot noise amplitude of the estimators, a finding we confirm with simulations. We demonstrate parameter estimation of the HI halo occupation models and advocate this framework for the interpretation of future experimental data, with the prospect of determining the HI masses of optical galaxy samples via the cross-correlation shot noise.Comment: 15 pages, 8 figures, 3 tables. Comments welcom

Relativistic Resonant Relations between Massive Black Hole Binary and Extreme Mass Ratio Inspiral

One component of a massive black hole binary (MBHB) might capture a small third body, and then a hierarchical, inclined triple system would be formed. With the post-Newtonian approximation including radiation reaction, we analyzed the evolution of the triple initially with small eccentricities. We found that an essentially new resonant relation could arise in the triple system. Here relativistic effects are crucial. Relativistic resonances, including the new one, stably work even for an outer MBHB of comparable masses, and significantly change the orbit of the inner small body.Comment: 9 pages, 5 figures, to appear in PR

Network formation of tissue cells via preferential attraction to elongated structures

Vascular and non-vascular cells often form an interconnected network in vitro, similar to the early vascular bed of warm blooded embryos. Our time-lapse recordings show that the network forms by extending sprouts, i.e., multicellular linear segments. To explain the emergence of such structures, we propose a simple model of preferential attraction to stretched cells. Numerical simulations reveal that the model evolves into a quasi-stationary pattern containing linear segments, which interconnect above the critical volume fraction of 0.2. In the quasi-stationary state the generation of new branches offset the coarsening driven by surface tension. In agreement with empirical data, the characteristic size of the resulting polygonal pattern is density-independent within a wide range of volume fractions

Brain GABA and Glutamate Concentrations Following Chronic Gabapentin Administration: A Convenience Sample Studied During Early Abstinence From Alcohol.

Gabapentin (GBP), a GABA analog that may also affect glutamate (Glu) production, can normalize GABA and Glu tone during early abstinence from alcohol, effectively treating withdrawal symptoms and facilitating recovery. Using in vivo magnetic resonance spectroscopy, we tested the degree to which daily GBP alters regional brain GABA and Glu levels in short-term abstinent alcohol-dependent individuals. Regional metabolite levels were compared between 13 recently abstinent alcohol-dependent individuals who had received daily GBP for at least 1 week (GBP+) and 25 matched alcohol-dependent individuals who had not received GBP (GBP-). Magnetic resonance spectra from up to five different brain regions were analyzed to yield absolute GABA and Glu concentrations. GABA and Glu concentrations in the parieto-occipital cortex were not different between GBP- and GBP+. Glu levels in anterior cingulate cortex, dorsolateral prefrontal cortex, and basal ganglia did not differ between GBP- and GBP+. However, in a subgroup of individuals matched on age, sex, and abstinence duration, GBP+ had markedly lower Glu in the frontal white matter (WM) than GBP-, comparable to concentrations found in light/non-drinking controls. Furthermore, lower frontal WM Glu in GBP+ correlated with a higher daily GBP dose. Daily GBP treatment at an average of 1,600 mg/day for at least 1 week was not associated with altered cortical GABA and Glu concentrations during short-term abstinence from alcohol, but with lower Glu in frontal WM. GBP for the treatment of alcohol dependence may work through reducing Glu in WM rather than increasing cortical GABA

Transient resonances in the inspirals of point particles into black holes

We show that transient resonances occur in the two body problem in general relativity, in the highly relativistic, extreme mass-ratio regime for spinning black holes. These resonances occur when the ratio of polar and radial orbital frequencies, which is slowly evolving under the influence of gravitational radiation reaction, passes through a low order rational number. At such points, the adiabatic approximation to the orbital evolution breaks down, and there is a brief but order unity correction to the inspiral rate. Corrections to the gravitational wave signal's phase due to resonance effects scale as the square root of the inverse of mass of the small body, and thus become large in the extreme-mass-ratio limit, dominating over all other post-adiabatic effects. The resonances make orbits more sensitive to changes in initial data (though not quite chaotic), and are genuine non-perturbative effects that are not seen at any order in a standard post-Newtonian expansion. Our results apply to an important potential source of gravitational waves, the gradual inspiral of white dwarfs, neutron stars, or black holes into much more massive black holes. It is hoped to exploit observations of these sources to map the spacetime geometry of black holes. However, such mapping will require accurate models of binary dynamics, which is a computational challenge whose difficulty is significantly increased by resonance effects. We estimate that the resonance phase shifts will be of order a few tens of cycles for mass ratios $\sim 10^{-6}$, by numerically evolving fully relativistic orbital dynamics supplemented with an approximate, post-Newtonian self-force.Comment: 4 pages, 1 figure, minor correction

Chemotactic Collapse and Mesenchymal Morphogenesis

We study the effect of chemotactic signaling among mesenchymal cells. We show that the particular physiology of the mesenchymal cells allows one-dimensional collapse in contrast to the case of bacteria, and that the mesenchymal morphogenesis represents thus a more complex type of pattern formation than those found in bacterial colonies. We finally compare our theoretical predictions with recent in vitro experiments

Icelandic debris flow and their relationship to martian gullies

Abstract not available