Transonic flutter and gust-response tests and analyses of a wind-tunnel model of a torsion free wing airplane

An exploratory study of a 1/5.5 size, complete airplane version of a torsion free wing (TFW) fighter aircraft was conducted. The TFW consisted of a wing/boom/canard assembly on each fuselage side that was interconnected by a common pivot shaft so that the TFW could rotate freely in pitch. The effect of the TFW was evaluated by comparing data obtained with the TFW free and the TFW locked to the fuselage. With the model mounted on cables to simulate an airplane free flying condition, flutter boundaries were measured at Mach number (M) from 0.85 to 1.0 and gust responses at M = 0.65 and 0.90. The critical flutter mode for the TFW free configuration was found experimentally to occur at M = 0.95 and had the rigid TFW pitch mode as its apparent aerodynamic driver

Laser-actuated mechanical device

Actuator is portable and can be used in high-temperature (over 500 C) environments by incorporating tungsten metal film and quartz window. Actuator can be triggered when it is not directly in laser beam path by utilizing fiber optics. It is advantageous for remotely switching ultra-high voltage systems

Optically actuated two position mechanical mover

An optically actuated mechanical mover adapted to be moved from an ambient position to an active position, is disclosed. The mechanical mover essentially comprises a piston/cylinder arrangement including a piston that is contained within an internal cylindrical chamber of a housing. The cylindrical chamber is configured to permit the piston to be moved for the length of the chamber as a work stroke. A lock pin extending through the piston, and diametrically opposed walls of the chamber housing, retain the piston in the ambient position at one end of the chamber. An actuator for producing a pressure or shock wave that drives the piston is positioned at the end of the chamber corresponding to the piston ambient position

Aircrew coordination and decisionmaking: Peer ratings of video tapes made during a full mission simulation

Six professionally active, retired captains rated the coordination and decisionmaking performances of sixteen aircrews while viewing videotapes of a simulated commercial air transport operation. The scenario featured a required diversion and a probable minimum fuel situation. Seven point Likert-type scales were used in rating variables on the basis of a model of crew coordination and decisionmaking. The variables were based on concepts of, for example, decision difficulty, efficiency, and outcome quality; and leader-subordin ate concepts such as person and task-oriented leader behavior, and competency motivation of subordinate crewmembers. Five-front-end variables of the model were in turn dependent variables for a hierarchical regression procedure. The variance in safety performance was explained 46%, by decision efficiency, command reversal, and decision quality. The variance of decision quality, an alternative substantive dependent variable to safety performance, was explained 60% by decision efficiency and the captain's quality of within-crew communications. The variance of decision efficiency, crew coordination, and command reversal were in turn explained 78%, 80%, and 60% by small numbers of preceding independent variables. A principle component, varimax factor analysis supported the model structure suggested by regression analyses

A shared mechanism of muscle wasting in cancer and Huntington's disease.

Skeletal muscle loss and dysfunction in aging and chronic diseases is one of the major causes of mortality in patients, and is relevant for a wide variety of diseases such as neurodegeneration and cancer. Muscle loss is accompanied by changes in gene expression and metabolism that lead to contractile impairment and likely affect whole-body metabolism and function. The changes may be caused by inactivity, inflammation, age-related factors or unbalanced nutrition. Although links with skeletal muscle loss have been found in diseases with disparate aetiologies, for example both in Huntingtons disease (HD) and cancer cachexia, the outcome is a similar impairment and mortality. This short commentary aims to summarize recent achievements in the identification of common mechanisms leading to the skeletal muscle wasting syndrome seen in diseases as different as cancer and HD. The latter is the most common hereditary neurodegenerative disorder and muscle wasting is an important component of its pathology. In addition, possible therapeutic strategies for anti-cachectic treatment will be also discussed in the light of their translation into possible therapeutic approaches for HD

Galaxies into the Dark Ages

We consider the capabilities of current and future large facilities operating at 2\,mm to 3\,mm wavelength to detect and image the [CII] 158\,$\mu$m line from galaxies into the cosmic "dark ages" ($z \sim 10$ to 20). The [CII] line may prove to be a powerful tool in determining spectroscopic redshifts, and galaxy dynamics, for the first galaxies. We emphasize that the nature, and even existence, of such extreme redshift galaxies, remains at the frontier of open questions in galaxy formation. In 40\,hr, ALMA has the sensitivity to detect the integrated [CII] line emission from a moderate metallicity, active star-forming galaxy [$Z_A = 0.2\,Z_{\odot}$; star formation rate (SFR) = 5\,$M_\odot$\,yr$^{-1}$], at $z = 10$ at a significance of 6$\sigma$. The next-generation Very Large Array (ngVLA) will detect the integrated [CII] line emission from a Milky-Way like star formation rate galaxy ($Z_{A} = 0.2\,Z_{\odot}$, SFR = 1\,$M_\odot$\,yr$^{-1}$), at $z = 15$ at a significance of 6$\sigma$. Imaging simulations show that the ngVLA can determine rotation dynamics for active star-forming galaxies at $z \sim 15$, if they exist. Based on our very limited knowledge of the extreme redshift Universe, we calculate the count rate in blind, volumetric surveys for [CII] emission at $z \sim 10$ to 20. The detection rates in blind surveys will be slow (of order unity per 40\,hr pointing). However, the observations are well suited to commensal searches. We compare [CII] with the [OIII] 88$\mu$m line, and other ancillary information in high $z$ galaxies that would aid these studies.Comment: 11pages, 8 figures, Accepted for the Astrophysical Journa