Alien Registration- Murphy, Annie M. (Portland, Cumberland County)

https://digitalmaine.com/alien_docs/21949/thumbnail.jp

Alien Registration- Murphy, Annie (Auburn, Androscoggin County)

https://digitalmaine.com/alien_docs/30011/thumbnail.jp

Alien Registration- Murphy, Annie M. (Presque Isle, Aroostook County)

https://digitalmaine.com/alien_docs/33709/thumbnail.jp

Towards Identifying Peer Supervision Competencies for Graduate-level Occupational Therapy Students: A Scoping Review

In the occupational therapy (OT) profession, peer supervision groups are recommended for professional development, lessening attrition, and relieving stress. Peer supervision is under researched, thus competencies to support this practice are unknown. The purpose of this scoping review was to: (1) summarize the research knowledge around peer supervision to support evidence-based practice in OT, (2) map supervision competencies and key themes in the literature, and (3) isolate peer supervision competencies that may be especially relevant to graduate-level OT students. The long-term aim of this research is to develop a framework for evidence-based peer supervision training. Researchers investigated the question: What competencies related to peer supervision, supervision in OT clinical education, and supervision in allied health are relevant to the education of graduate-level OT students? Using a six-step methodological framework, a scoping review of empirical, conceptual, and grey literature was conducted. Studies relevant to peer supervision, supervision in OT clinical education, and supervision practices in allied health professions were searched and appraised, yielding 15 high quality studies. Competencies were extracted and mapped, resulting in the following OT peer supervision competencies: flexibility, professional enculturation, providing constructive feedback, psychosocial support, teaching, and clinical skill acquisition. Findings suggest OT peer supervision competencies center on skillful relationship abilities, as supervision skills are not innate, not dependent on clinical skill, and typically need to be taught. This study warrants the need for additional efforts around supervision practices

Effects of commercial clam aquaculture on biogeochemical cycling in shallow coastal ecosystems

The bivalve aquaculture industry is expanding worldwide; sustainability requires improved understanding of its interactions with the environment. As suspension feeders, bivalves, such as clams, reduce primary production through feeding, and thus dampen eutrophication. Additionally, enhanced rates of denitrification, the microbial removal of reactive nitrogen, have been reported in bivalve sediments due to increased organic matter supply through biodeposition; another potential, yet indirect, control on eutrophication. Simultaneously, bivalves can influence local ‘bottom-up’ effects on production by enhancing nutrient regeneration through excretion and microbial mineralization of biodeposits. At clam aquaculture sediments, respiration and nutrient regeneration rates were significantly higher compared to uncultivated sediments. The enhanced nutrient recycling facilitated by clam aquaculture directly fueled macroalgal production, which proliferate on the shallow predator-exclusion nets commonly used by US aquaculturists. The effect of clams on denitrification and dissimilatory nitrate reduction to ammonium (DNRA), microbial processes that compete for nitrate, was site and season dependent; strongly influenced by nitrate concentrations relative to organic carbon availability. DNRA was favored over denitrification in environments with low nitrate (i.e. Cherrystone Inlet, VA) while denitrification increased above DNRA in high nitrate conditions (i.e. low salinity sites in Sacca di Goro, Italy). As a bioextractive practice, bivalve aquaculture is a net sink for nitrogen via harvest, however, depending on the food source (e.g. external or internal), bivalves may increase nitrogen and subsequently production on a local scale. These results highlight the need to assess both nitrogen removal and regeneration pathways associated with bivalve aquaculture to determine the overall effect on eutrophication

Response to Comments of Peter G. Mantle

The apparently high yield of testis tumors (25%) in rats exposed long-term to Ochratoxin A (OTA) is uninterpretable without data on tumor yield in unexposed rats. Conversely, our demonstration that prenatal exposure to OTA induces DNA adducts in the testes of newborn mice and the absence of these adducts in the testes of mice not exposed prenatally to OTA, is evidence for the presumptive carcinogenicity of OTA in the testis. Together with recent data showing that prenatal exposure to OTA depresses expression of DMRT1, a tumor suppressor gene in the testis, our findings suggest that OTA may be a cause of testicular cancer

The Resolved Radio--FIR Correlation in Nearby Galaxies with Herschel and Spitzer

We investigate the correlation between the far-infrared (FIR) and radio continuum emission from NGC6946 on spatial scales between 0.9 and 17 kpc. We use the Herschel PACS (70, 100, 160$\mu$m) and SPIRE (250$\mu$m) data from the KINGFISH project. Separating the free-free and synchrotron components of the radio continuum emission, we find that FIR is better correlated with the free-free than the synchrotron emission. Compared to a similar study in M33 and M31, we find that the scale dependence of the synchrotron--FIR correlation in NGC6946 is more similar to M31 than M33. The scale dependence of the synchrotron--FIR correlation can be explained by the turbulent-to-ordered magnetic field ratio or, equivalently, the diffusion length of the cosmic ray electrons in these galaxies.Comment: 4 pages, 3 figures, The Spectral Energy Distribution of Galaxies Proceedings IAU Symposium No. 284, 2011, R.J. Tuffs & C.C.Popescu, ed

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.

Aging is a contributing factor in cancer occurrence. We recently demonstrated that systemic immunotherapy (IT) administration in aged, but not young, mice resulted in induction of rapid and lethal cytokine storm. We found that aging was accompanied by increases in visceral fat similar to that seen in young obese (ob/ob or diet-induced obese [DIO]) mice. Yet, the effects of aging and obesity on inflammatory responses to immunotherapeutics are not well defined. We determine the effects of adiposity on systemic IT tolerance in aged compared with young obese mice. Both young ob/ob- and DIO-generated proinflammatory cytokine levels and organ pathologies are comparable to those in aged ad libitum mice after IT, culminating in lethality. Young obese mice exhibited greater ratios of M1/M2 macrophages within the peritoneal and visceral adipose tissues and higher percentages of TNF(+) macrophages in response to αCD40/IL-2 as compared with young lean mice. Macrophage depletion or TNF blockade in conjunction with αCD40/IL-2 prevented cytokine storms in young obese mice and protected from lethality. Calorie-restricted aged mice contain less visceral fat and displayed reduced cytokine levels, protection from organ pathology, and protection from lethality upon αCD40/IL-2 administration. Our data demonstrate that adiposity is a critical factor in the age-associated pathological responses to systemic anti-cancer IT