On the height variation of the E-region cowling conductivity ? effect of charged dust particles

International audienceHeight profiles of the Cowling conductivity in the electrojet region, estimated using the atmospheric parameters given by the existing models like CIRA or MSIS and measured electron density profiles, consistently show the heights of the electrojet current intensity peak to be more than 3 km below those estimated from in-situ measurements using magnetometers on board sounding rockets. Kulkarni and Muralikrishna (2005) attempted to explain this to be due to the effect of neutral dust particles. They reported that neutral dust particles, when they exist in sufficient numbers, can modify the collision parameters, especially in the lower E-region, where dust particles of meteoric origin are known to exist in large numbers, and thereby can modify the Cowling conductivity profile in the electrojet region. This work is extended here to include the effect of charged dust particles. Dust particles can become charged negatively by the attachment of ambient free electrons, and can thus reduce the number density of free electrons especially below the electrojet peak. This can alter the vertical profile of the east-west Hall current driven by the vertical Hall polarization field, thereby causing a net reduction in the electrojet current. Such a decrease in the electrojet current may be observed on the ground magnetograms. This mechanism, as proposed here, can operate only during periods of strong meteor shower activity, when the dust particle density at the assumed deposit height of 103 km can reach extreme values (for example, 5×104 cm?3 of 1-µm diameter dust particles). Such a dense dust layer may even cause a reversal in the normally upward vertical Hall polarization field, within the dust layer, causing a reversal of the electrojet currents below the current peak

Effect of Diluents on the Extraction of Mercury(II) by n-Butyl Acetate

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Surgical management of vaginal agenesis using a modified Mc Indoe’s technique: VIMS experience

Background: Mullerian agenesis is a challenge to reconstructive surgeons. In order to create a new vagina that mimic the normal one in size, lining and appearance, multiple techniques have been designed; among these techniques Mc Indoe’s vaginoplasty represents the simplest one with good results. Mc Indoe’s operation which involves the creation of a space between bladder and rectum, insertion of a mould covered with split-thickness skin graft into that neo-vaginal space, and use of postoperative vaginal mould for dilation and to avoid stenosis. However, many modifications have been introduced in time in an attempt to increase the success rates. The purpose of vaginal agencies treatment is to create an adequate passage for penetration during sexual intercourse.Methods: Between Jan 2010 to June 2017, ten patients with vaginal agenesis were admitted to Dept of Obstetrics and Gynaecology, VIMS Ballari for vaginal reconstruction. All cases underwent a modified Mc Indoe’s technique, and follow up was done for one year.Results: All ten cases of vaginal agenesis underwent vaginal reconstruction by modified Mc Indoe's technique. Post-operative vaginal length varied from 5 to 7 cm in patients who used mould regularly. Successful skin graft take was achieved in 6 cases. one case of perforation of rectum and one case of vaginal stricture was noted.Conclusions: To optimize sexual comfort, the clinical management of women with vaginal agenesis must be multidisciplinary and individually tailored. Our findings suggest that the modified Mc Indoe’s technique is a simple, effective procedure for the treatment of vaginal agenesis, but proper mould usage after surgery remains the cornerstone of the treatment

ASSESMENT OF QUALITY OF LIFE AND OXIDATIVE STRESS IN TUBERCULOSIS PATIENTS VISITING DIRECTLY OBSERVED TREATMENT SHORT COURSE CENTRES OF WARANGAL

ABSTRACTObjectives: Tuberculosis (TB) is a disease associated with a wide range of respiratory symptoms. It remains a major public health problem worldwide.In TB, oxidative stress is a result of tissue inflammation, poor dietary intake of micronutrients due to illness, and free radical burst from activatedmacrophages. In recent years, efforts have been dedicated for assessing the health-related quality of life (HRQoL) in TB patients. The objectives of thestudy were to evaluate the impairment of HRQoL in TB patients using by DR-12 questionnaire and to estimate oxidative stress parameters such asmalondialdehyde (MDA), glutathione (GSH), vitamins A, and C in TB patients.Methods: A total of 142 patients meeting the study criteria were recruited in the study to evaluate HRQOL. The patients were administered withDR-12 questionnaire at 0 week, 4 weeks and at the end of intensive phase of the treatment. A paired t-test was applied and a p<0.05 was consideredas significant. 40 patients meeting the study criteria were recruited for assessment of oxidative stress parameters. The blood samples were assessedfor the concentration of MDA, GSH, vitamin A, and vitamin C using suitable methods.Results: A significantly higher HRQOL scores were observed at the end of intensive phase of the treatment for both pulmonary and extrapulmonaryTB patients. There was a significant improvement in their QOL (p<0.05). An increased oxidative stress was obtained in plasma of TB patients ascompared to normal healthy controls. There was a significant increase in the MDA levels of TB patients (7 times greater than control) when comparedto normal population. There was a double decrease in GSH and vitamin A concentrations in TB cases compared with controls. The plasma levels ofvitamin C in TB cases obtained thrice lesser in TB cases than the control population.Conclusion: The study showed that in TB patients free radical activity is quite high and antioxidant levels are low. A suitable antioxidant therapy mayimprove QoL and prove beneficial supplementation for fast recovery.Keywords: Tuberculosis, Health-related quality of life, Directly observed treatment short course, DR-12 score, Antioxidants, Free radicals

Spectrophotometric Determination of Os(VIII) with Thioglycollic Acid

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Micropropagation of White Palash tree (Butea monosperma (Lam.) Taub. Var. lutea (Witt.)).

An efficient and reproducible protocol is established for rapid in vitro multiplication of an endangered, valuable medicinal plant, Butea monosperma (Lam.) Taub. Var. lutea, through cotyledonary nodes of mature seeds. Among various cytokinins tested, high frequency of direct shoot regeneration was induced on Murashige and skoog (MS) medium supplemented with BAP, which found to be more effective and showed optimal response at 2 mg/L with a maximum number of 8.35±0.32 multiple shoots per explant. Proliferation of shoots was established by repeated subculturing on to same regeneration medium with 2-3 weeks of time interval. Rooting of regenerated shoots was achieved after 3 weeks of culture on MS medium containing 1 mg/L IBA. In vitro raised plantlets were transferred to pots containing sterilized soil and vermiculate mixture in 1:1 ratio and then shifted to greenhouse. Well established plantlets exhibited 75% survival rate

Spectrophotometric Investigation of Os(VI)- Thiocyanate Complex

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Colocalization of intranuclear lamin foci with RNA splicing factors

The lamins form a fibrous network underlying the inner nuclear membrane termed the nuclear lamina. In order to gain insights into the role of lamins in nuclear organization, we have characterized a monoclonal antibody (LA-2H10) raised against recombinant rat lamin A that labels nuclei in a speckled pattern in all cells of unsynchronized populations of HeLa and rat F-111 fibroblast cells, unlike the typical nuclear periphery staining by another monoclonal antibody to lamin A, LA-2B3. In immunolocalization studies the lamin A speckles or foci were found to colocalize with the RNA splicing factors SC-35 and U5-116 kD, but not with p80 coilin found in coiled bodies. Lamin B1 was also associated with these foci. These foci dispersed when cells entered mitosis and reformed during anaphase. The differential reactivity of LA-2H10 and LA-2B3 was retained after nuclei were extracted with detergents, nucleases and salt to disrupt interactions of lamins with chromatin and other nuclear proteins. Using deletion fragments of recombinant lamin A, the epitope recognized by LA-2H10 was located between amino acids 171 and 246. Our findings are consistent with a structural role for lamins in supporting nuclear compartments containing proteins involved in RNA splicing