EMPLOYEE PERFORMANCE APPRAISAL SYSTEM BASED ON RANKING AND REVIEWS

Objective: In many organizations, employee data have to be maintained and utilized for many purposes. Here, in this paper, we are going to use such data to calculate an employee's performance.Methods: This employee data may be converted into useful information using data mining techniques such as K-means and decisions tree. K-means is used to find the rank of the employee means that the employee may come under in his criteria. Decision tree is used to find the review of an employee means that the employee needs improvement or he/she meets expectation.Results: This algorithm when utilized can identify the top employee who can be considered for appraisal or the eligible candidates for promotion. Hence, these algorithms such as K-mean and decision tree that help to find best employees for any association and help us to take a good decision in less time.Conclusion: There are various factors which should be considered and are limited to this algorithm, so human intervention is required to consider those factors. However, ranking and appraisal are seen in many companies, and this algorithm will definitely identify the potential candidates

Molecular phylogeny of silkmoths reveals the origin of domesticated silkmoth, Bombyx mori from chinese Bombyx mandarina and paternal inheritance of Antheraea proylei mitochondrial DNA

Molecular phylogeny of some of the economically important silkmoths was derived using three mitochondrial genes, 12S rRNA, 16S rRNA, and COI, and the control region (CR). Maximum likelihood (ML) analyses showed two distinct clades, one consisting of moths from Bombycidae family and the other from Saturniidae family. The mitochondrial CR showed length polymorphisms with indels. The ML analyses for complete mitochondrial genome sequences of Bombyx mori (strains Aojuku, C108, Backokjam, and Xiafang), Japanese and Chinese strains of B. mandarina (Japanese mandarina and Chinese mandarina) and, Antheraea pernyi revealed two distinct clades, one comprising of B. mori strains and the other with B. mandarina, and A. pernyi forming an outgroup. Pairwise distances revealed that all of the strains of B. mori studied are closer to Chinese than to Japanese mandarina. Phylogenetic analyses based on whole mitochondrial genome sequences, the finding of a tandem triplication of a 126 bp repeat element only in Japanese mandarina, and chromosome number variation in B. mandarina suggest that B. mori must have shared its recent common ancestor with Chinese mandarina. Another wild species of the Bombycidae family, Theophila religiosa, whose phylogenetic status was not clear, clustered together with the other bombycid moths in the study. Analysis of the interspecific hybrid, A. proylei gave evidence for paternal inheritance of mitochondrial DNA

Genetic evidence from Indian red jungle fowl corroborates multiple domestication of modern day chicken

<p>Abstract</p> <p>Background</p> <p>Domestication of chicken is believed to have occurred in Southeast Asia, especially in Indus valley. However, non-inclusion of Indian red jungle fowl (RJF), <it>Gallus gallus murghi </it>in previous studies has left a big gap in understanding the relationship of this major group of birds. In the present study, we addressed this issue by analyzing 76 Indian birds that included 56 <it>G. g. murghi </it>(RJF), 16 <it>G. g. domesticus </it>(domestic chicken) and 4 <it>G. sonneratii </it>(Grey JF) using both microsatellite markers and mitochondrial D-loop sequences. We also compared the D-loop sequences of Indian birds with those of 779 birds obtained from GenBank.</p> <p>Results</p> <p>Microsatellite marker analyses of Indian birds indicated an average F_STof 0.126 within <it>G. g. murghi</it>, and 0.154 within <it>G. g. domesticus </it>while it was more than 0.2 between the two groups. The microsatellite-based phylogenetic trees showed a clear separation of <it>G. g. domesticus </it>from <it>G. g. murghi</it>, and <it>G. sonneratii</it>. Mitochondrial DNA based mismatch distribution analyses showed a lower Harpending's raggedness index in both <it>G. g. murghi </it>(0.001515) and in Indian <it>G. g. domesticus </it>(0.0149) birds indicating population expansion. When meta analysis of global populations of 855 birds was carried out using median joining haplotype network, 43 Indian birds of <it>G. g. domesticus </it>(19 haplotypes) were distributed throughout the network sharing haplotypes with the RJFs of different origins.</p> <p>Conclusion</p> <p>Our results suggest that the domestication of chicken has occurred independently in different locations of Asia including India. We found evidence for domestication of Indian birds from <it>G. g. spadiceus </it>and <it>G. g. gallus </it>as well as from <it>G. g. murghi</it>, corroborating multiple domestication of Indian and other domestic chicken. In contrast to the commonly held view that RJF and domestic birds hybridize in nature, the present study shows that <it>G. g. murghi </it>is relatively pure. Further, the study also suggested that the chicken populations have undergone population expansion, especially in the Indus valley.</p

Determination of V(V) & Cr(VI) in Presence of Chloride

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Hairpins in the conformations of a confined polymer

If a semiflexible polymer confined to a narrow channel bends around by 180 degrees, the polymer is said to exhibit a hairpin. The equilibrium extension statistics of the confined polymer are well understood when hairpins are vanishingly rare or when they are plentiful. Here we analyze the extension statistics in the intermediate situation via experiments with DNA coated by the protein RecA, which enhances the stiffness of the DNA molecule by approximately one order of magnitude. We find that the extension distribution is highly non-Gaussian, in good agreement with Monte Carlo simulations of confined discrete wormlike chains. We develop a simple model that qualitatively explains the form of the extension distribution. The model shows that the tail of the distribution at short extensions is determined by conformations with one hairpin.Comment: Revised version. 22 pages, 7 figures, 2 tables, supplementary materia

YBCO-buffered NdBCO film with higher thermal stability in seeding REBCO Growth

In this work, we report a strengthened superheating effect caused by a buffering YBa2Cu3Oy (Y123 or YBCO) layer in the Nd1+xBa2-xCu3O7-y (Nd123 or NdBCO) thin film with MgO substrate (i.e., NdBCO/YBCO/MgO thin film). In the cold-seeding melt-textured (MT) growth, the NdBCO/YBCO/MgO film presented an even higher superheating level, about 20 {\deg}C higher than that of non-buffered NdBCO film (i.e., NdBCO/MgO film). Using this NdBCO/YBCO/MgO film as seeds and undergoing a maximum processing temperature (Tmax) up to 1120 {\deg}C, we succeeded in growing various RE1+xBa2-xCu3O7-y (REBCO, RE=rare elements) bulk superconductors, including Gd1+xBa2-xCu3O7-y (GdBCO), Sm1+xBa2-xCu3O7-y (SmBCO) and NdBCO that have high peritectic temperatures (Tp). The pole figure (X-Ray \phi-scan) measurement reveals that the NdBCO/YBCO/MgO film has better in-plane alignment than the NdBCO/MgO film, indicating that the induced intermediate layer improves the crystallinity of the NdBCO film, which could be the main origin of the enhanced thermal stability. In short, possessing higher thermal stability and enduring a higher Tmax in the MT process, the NdBCO/YBCO/MgO film is beneficial to the growth of bulk superconductors in two aspects: (1) broad application for high-Tp REBCO materials; (2) effective suppression against heterogeneous nucleation, which is of great assistance in growing large and high-performance REBCO crystals.Comment: 9 pages, 4 figure

Evaluation of Wound Healing Properties of Bioactive Fractions from the Extract of Butea monosperma (Lam) Stem Bark.

The study aims to evaluate the wound healing properties of bioactive fractions from the extract of Butea monosperma (Lam) stem bark. In this study the stem bark powder was extracted with ethanol, further the ethanolic extract was fractionated with different solvents (petroleum ether, benzene, chloroform and acetone) in increasing order of polarity. Thus prepared extracts were subjected to preliminary phytochemical analysis. The wound healing activity of the ethanolic extract and the fractions isolated from the stem bark of Butea monosperma were evaluated in excision, incision and dead space wound healing models using Albino wistar rats. The wound healing activity was assessed by the breaking strength in case of incision wounds, epithelialization and wound contraction in case of excision wound and granulation tissue dry weight, breaking strength and hydroxyproline content in case of dead space wound. The ethanolic extract and the acetone fraction showed the significant wound healing activity on all three wound models. The phytochemical investigations revealed the presence of alkaloids, tannins, flavonoids, phenolic compounds and steroids. The increased rate of wound contraction and hydroxyproline content in the ethanolic extract and the acetone fraction treated animals provides a scientific base to the ethno medicinal use of Butea monosperma, which is largely attributable to the additive or synergistic effect of their constituents. Keywords: Butea monosperma, Dead space wound, Excision wound, Incision wound

Evaluation of Wound Healing Properties of Bioactive Fractions from the Extract of Butea monosperma (Lam) Stem Bark.

The study aims to evaluate the wound healing properties of bioactive fractions from the extract of Butea monosperma (Lam) stem bark. In this study the stem bark powder was extracted with ethanol, further the ethanolic extract was fractionated with different solvents (petroleum ether, benzene, chloroform and acetone) in increasing order of polarity. Thus prepared extracts were subjected to preliminary phytochemical analysis. The wound healing activity of the ethanolic extract and the fractions isolated from the stem bark of Butea monosperma were evaluated in excision, incision and dead space wound healing models using Albino wistar rats. The wound healing activity was assessed by the breaking strength in case of incision wounds, epithelialization and wound contraction in case of excision wound and granulation tissue dry weight, breaking strength and hydroxyproline content in case of dead space wound. The ethanolic extract and the acetone fraction showed the significant wound healing activity on all three wound models. The phytochemical investigations revealed the presence of alkaloids, tannins, flavonoids, phenolic compounds and steroids. The increased rate of wound contraction and hydroxyproline content in the ethanolic extract and the acetone fraction treated animals provides a scientific base to the ethno medicinal use of Butea monosperma, which is largely attributable to the additive or synergistic effect of their constituents. Keywords: Butea monosperma, Dead space wound, Excision wound, Incision wound

Regulation of Oxidized Base Repair in Human Chromatin by Posttranslational Modification

Base excision repair (BER) is the major pathway for the repair of oxidized bases and apurinic/apyrimidinic (abasic; AP) sites produced by reaction with reactive oxygen/nitrogen species (ROS/RNS). These metabolites are generated spontaneously by endogenous cellular processes and also by environmental agents. Because most of these lesions are promutagenic, linked to diverse disease-associated somatic mutations, as well as heritable single nucleotide polymorphisms (SNPs) in the normal human population, their prompt repair is warranted. Impairment of repair leading to mutation, a hallmark of cancer, underscores the essentiality of BER for maintaining genome integrity in humans and other mammals. In mammals, repair of oxidized bases and other BER substrates is initiated by DNA glycosylases (DGs), which excise the damaged bases and cleave the DNA strands at the resulting AP sites, followed by sequential end processing, gap-filling DNA synthesis, and ligation. In vitro BER performed with naked DNA substrates has been extensively studied, which delineates its basic mechanistic steps and subpathways. However, recent interest is directed to unraveling BER in cell chromatin, including its regulation via posttranslational modifications (PTMs), which occurs possibly in concert with nucleosome remodeling. Emerging reports on various PTMs of BER enzymes indicate that the PTMs, while dispensable for the enzymatic activity, regulate overall repair by modulating interactions with other repair proteins and chromatin factors, assembly of BER complexes, as well as turnover of the proteins, and may ultimately dictate the cellular phenotype. Here, we discuss recent advances in the BER field by reviewing the PTMs and how they regulate BER in chromatin