Individualized Education Plan Applied to Physical Education: Validation of Inventory in Portuguese Version

From specific needs of the countries of origin, an inventory called "Individualized Education Plan applied to Physical Education" (IEP-PE) was developed through international collaboration by faculty researchers from North and South America. Versionsin English, Spanish and Portuguese are being simultaneously validated. This essay aims to validate the Portuguese version of the Individualized Education Plan (IEP-PE) specifically designed for the area of physical education, in order to direct the planning of actions in this context. This is an exploratory study involving content validation of the IEP-PE. The invitation letter and the criteria for their validation of the instrument were sent to 10 Brazilian judges. Validated Portuguese version of IEP-PE, as well as the adjustments arising from the analysis of the judges, will be presented in this article

Author Correction: Ecology, evolution and spillover of coronaviruses from bats.

In the past two decades, three coronaviruses with ancestral origins in bats have emerged and caused widespread outbreaks in humans, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the first SARS epidemic in 2002–2003, the appreciation of bats as key hosts of zoonotic coronaviruses has advanced rapidly. More than 4,000 coronavirus sequences from 14 bat families have been identified, yet the true diversity of bat coronaviruses is probably much greater. Given that bats are the likely evolutionary source for several human coronaviruses, including strains that cause mild upper respiratory tract disease, their role in historic and future pandemics requires ongoing investigation. We review and integrate information on bat–coronavirus interactions at the molecular, tissue, host and population levels. We identify critical gaps in knowledge of bat coronaviruses, which relate to spillover and pandemic risk, including the pathways to zoonotic spillover, the infection dynamics within bat reservoir hosts, the role of prior adaptation in intermediate hosts for zoonotic transmission and the viral genotypes or traits that predict zoonotic capacity and pandemic potential. Filling these knowledge gaps may help prevent the next pandemic

Individualized Education Plan Applied to Physical Education: Validation of Inventory in Portuguese Version

From specific needs of the countries of origin, an inventory called "Individualized Education Plan applied to Physical Education" (IEP-PE) was developed through international collaboration by faculty researchers from North and South America. Versionsin English, Spanish and Portuguese are being simultaneously validated. This essay aims to validate the Portuguese version of the Individualized Education Plan (IEP-PE) specifically designed for the area of physical education, in order to direct the planning of actions in this context. This is an exploratory study involving content validation of the IEP-PE. The invitation letter and the criteria for their validation of the instrument were sent to 10 Brazilian judges. Validated Portuguese version of IEP-PE, as well as the adjustments arising from the analysis of the judges, will be presented in this article

Plano de Ensino Individualizado Aplicado à Educação Física: Validação de Inventário na Versão em Português

A partir de demandas específicas dos países de origem, o inventário denominado “Plano de Ensino Individualizado aplicado à Educação Física” (PEI-EF) foi elaborado em sistema de colaboração internacional por professores pesquisadores das Américas do Norte e do Sul. As versões em inglês, espanhol e português estão sendo validadas simultaneamente. Este ensaio tem como objetivo validar aversão em português do Plano de Ensino Individualizado especificamente concebido para o contexto da Educação Física Escolar (PEI-EF), visando direcionar o planejamento das ações nesse âmbito. Trata-se de um estudo exploratório envolvendo validação de conteúdo do PEIEF. A carta-convite e os respectivos critérios de validação do instrumento foram encaminhados a 10 juízes brasileiros. No presente artigo será apresentada a versão validada em Português do PEI-EF, bem como os respectivos ajustes decorrentes das análises dos juízes

Plano de Ensino Individualizado Aplicado à Educação Física: Validação de Inventário na Versão em Português

A partir de demandas específicas dos países de origem, o inventário denominado “Plano de Ensino Individualizado aplicado à Educação Física” (PEI-EF) foi elaborado em sistema de colaboração internacional por professores pesquisadores das Américas do Norte e do Sul. As versões em inglês, espanhol e português estão sendo validadas simultaneamente. Este ensaio tem como objetivo validar aversão em português do Plano de Ensino Individualizado especificamente concebido para o contexto da Educação Física Escolar (PEI-EF), visando direcionar o planejamento das ações nesse âmbito. Trata-se de um estudo exploratório envolvendo validação de conteúdo do PEIEF. A carta-convite e os respectivos critérios de validação do instrumento foram encaminhados a 10 juízes brasileiros. No presente artigo será apresentada a versão validada em Português do PEI-EF, bem como os respectivos ajustes decorrentes das análises dos juízes

Programa de formação de colegas tutores: a tutoria no processo de inclusão escolar nas aulas de Educação Física

A presente pesquisa pretendeu analisar o efeito da atuação do colega tutor junto a um estudante com deficiência nas aulas de Educação Física. Este estudo apoiou-se em abordagem metodológica de natureza qualitativa, caracterizada como estudo de caso. A pesquisa foi desenvolvida em escola da Rede Municipal de Ensino localizada no interior do Estado da Bahia. Os participantes desta pesquisa foram: um estudante com deficiência intelectual associada ao transtorno do espectro autista e cinco colegas tutores. Como instrumento de coleta de dados, utilizou-se a observação sistemática ou estruturada, não participante, em ambiente natural. Foram realizadas filmagens das aulas de Educação Física, antes e após o treinamento dos tutores. Os resultados demonstraram que a intervenção dos colegas tutores, com estratégias de ensino, culminou no aumento do nível de participação do estudante com deficiência, contribuindo com o processo de inclusão nas aulas de Educação Física

Randomized Trial of Lisinopril Versus Carvedilol to Prevent Trastuzumab Cardiotoxicity in Patients With Breast Cancer

BackgroundTrastuzumab is highly effective for human epidermal growth factor receptor type 2 (HER2)-positive breast cancer but is associated with a decline in left ventricular ejection fraction.ObjectivesThe purpose of this study was to determine whether angiotensin-converting enzyme inhibitors or beta-blockers reduce the rate of trastuzumab-induced cardiotoxicity (left ventricular ejection fraction decrease >10%, or >5% if below 50%) and limit treatment interruptions.MethodsIn this double-blind, multicenter, placebo-controlled trial, cardiotoxicity and treatment interruptions in patients with HER2-positive breast cancer treated with trastuzumab for 12 months were evaluated over a 2-year period. Patients were stratified by anthracycline use and then randomized to receive lisinopril, carvedilol, or placebo.ResultsThe study included 468 women, age 51 ± 10.7 years. For the entire cohort, cardiotoxicity was comparable in the 3 arms and occurred in 32% of patients on placebo, 29% on carvedilol, and 30% on lisinopril. For patients receiving anthracyclines, the event rates were higher in the placebo group (47%) than in the lisinopril (37%) and the carvedilol (31%) groups. Cardiotoxicity-free survival was longer on both carvedilol (hazard ratio: 0.49; 95% confidence interval: 0.27 to 0.89; p = 0.009) and lisinopril (hazard ratio: 0.53; 95% confidence interval: 0.30 to 0.94; p = 0.015) than on placebo. In the whole cohort, as well as in the anthracycline arm, patients on active therapy with either angiotensin-converting enzyme inhibitor or beta-blockers experienced fewer interruptions in trastuzumab than those on placebo.ConclusionsIn patients with HER2-positive breast cancer treated with trastuzumab, both lisinopril and carvedilol prevented cardiotoxicity in patients receiving anthracyclines. For such patients, lisinopril or carvedilol should be considered to minimize interruptions of trastuzumab. (Lisinopril or Coreg CR in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab; NCT01009918)

Ecology, evolution and spillover of coronaviruses from bats.

In the past two decades, three coronaviruses with ancestral origins in bats have emerged and caused widespread outbreaks in humans, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the first SARS epidemic in 2002-2003, the appreciation of bats as key hosts of zoonotic coronaviruses has advanced rapidly. More than 4,000 coronavirus sequences from 14 bat families have been identified, yet the true diversity of bat coronaviruses is probably much greater. Given that bats are the likely evolutionary source for several human coronaviruses, including strains that cause mild upper respiratory tract disease, their role in historic and future pandemics requires ongoing investigation. We review and integrate information on bat-coronavirus interactions at the molecular, tissue, host and population levels. We identify critical gaps in knowledge of bat coronaviruses, which relate to spillover and pandemic risk, including the pathways to zoonotic spillover, the infection dynamics within bat reservoir hosts, the role of prior adaptation in intermediate hosts for zoonotic transmission and the viral genotypes or traits that predict zoonotic capacity and pandemic potential. Filling these knowledge gaps may help prevent the next pandemic