1,969 research outputs found

    Reproducibility of scientific workflows execution using cloud-aware provenance (ReCAP)

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    © 2018, Springer-Verlag GmbH Austria, part of Springer Nature. Provenance of scientific workflows has been considered a mean to provide workflow reproducibility. However, the provenance approaches adopted so far are not applicable in the context of Cloud because the provenance trace lacks the Cloud information. This paper presents a novel approach that collects the Cloud-aware provenance and represents it as a graph. The workflow execution reproducibility on the Cloud is determined by comparing the workflow provenance at three levels i.e., workflow structure, execution infrastructure and workflow outputs. The experimental evaluation shows that the implemented approach can detect changes in the provenance traces and the outputs produced by the workflow

    Spontaneous Aortic Thrombosis Causing Left Main Coronary Occlusion in a Man With Secondary Polycythemia

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    Community of Practice Theory Approach to Understanding Factors Influencing Informal M-Health Use among Janitors in an IT-Rich Context

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    Janitors have peculiar job responsibilities and adjoining healthcare needs. However, they are usually not allowed access to healthcare facilities of their organizations. Therefore, we assumed that janitors would use informal M-Health without conviction. Surprisingly, we observe that janitors do not use informal M-Health. Our observation is more worrisome because the janitors work in an IT-rich organization that could offer them the platform to use informal M-Health. Our assumption and observation indicate the need to understand the factors influencing the use of informal M-Health among janitors. We adopted the community of practice theory and the interpretive case study method and collected research data through interviews and participatory observation. Our findings reveal the factors that influence the use of informal M-Health. We conclude that janitors may need to use informal M-Health if they are continued to be deprived of access to formal healthcare outlets

    An alternative conformation of ERβ bound to estradiol reveals H12 in a stable antagonist position

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    FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOThe natural ligand 17β-estradiol (E2) is so far believed to induce a unique agonist-bound active conformation in the ligand binding domain (LBD) of the estrogen receptors (ERs). Both subtypes, ERα and ERβ, are transcriptionally activated in the presence o7FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO2014/22007-02013/08293-72012/24750-6301981/2011-6This work was supported by the São Paulo Research Foundation FAPESP (grants 2014/22007-0, 2013/08293-7, 2012/24750-6) and by CNPq (grant 301981/2011-6
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