What pops out in positional priming of pop-out: insights from event-related EEG lateralizations

It is well established that, in visual pop-out search, reaction time (RT) performance is influenced by cross-trial repetitions versus changes of target-defining attributes. One instance of this is referred to as “positional priming of pop-out” (pPoP; Maljkovic and Nakayama, 1996). In positional PoP paradigms, the processing of the current target is examined depending on whether it occurs at the previous target or a previous distractor location, relative to a previously empty location (“neutral” baseline), permitting target facilitation and distractor inhibition to be dissociated. The present study combined RT measures with specific sensory- and motor-driven event-related lateralizations to track the time course of four distinct processing levels as a function of the target’s position across consecutive trials. The results showed that, relative to targets at previous target and “neutral” locations, the appearance of a target at a previous distractor location was associated with a delayed build-up of the posterior contralateral negativity wave, indicating that distractor positions are suppressed at early stages of visual processing. By contrast, presentation of a target at a previous target, relative to “neutral” and distractor locations, modulated the elicitation of the subsequent stimulus-locked lateralized readiness potential wave, indicating that post-selective response selection is facilitated if the target occurred at the same position as on the previous trial. Overall, the results of present study provide electrophysiological evidence for the idea that target location priming (RT benefits) does not originate from an enhanced coding of target saliency at repeated (target) locations; instead, they arise (near-) exclusively from processing levels subsequent to focal-attentional target selection

Out of equilibrium quantum field dynamics of an initial thermal state after a change in the external field

The effects of the initial temperature in the out of equilibrium quantum field dynamics in the presence of an homogeneous external field are investigated. We consider an initial thermal state of temperature T for a constant external field J. A subsequent sign flip of the external field, J to -J, gives rise to an out of equilibrium nonperturbative quantum field dynamics. The dynamics is studied here for the symmetry broken lambda(Phi^2)^2 scalar N component field theory in the large N limit. We find a dynamical effective potential for the expectation value that helps to understand the dynamics. The dynamics presents two regimes defined by the presence or absence of a temporal trapping close to the metastable equilibrium position of the potential. The two regimes are separated by a critical value of the external field that depends on the initial temperature. The temporal trapping is shorter for larger initial temperatures or larger external fields. Parametric resonances and spinodal instabilities amplify the quantum fluctuations in the field components transverse to the external field. When there is a temporal trapping this is the main mechanism that allows the system to escape from the metastable state for large N. Subsequently backreaction stops the growth of the quantum fluctuations and the system enters a quasiperiodic regime.Comment: LaTeX, 19 pages, 12 .eps figures, improved version to appear in Phys Rev

Reducing Global Warming and Adapting to Climate Change: The Potential of Organic Agriculture

Climate change mitigation is urgent and adaptation to climate change is crucial, particularly in agriculture, where food security is at stake. Agriculture, currently responsible for 20-30% of global greenhouse gas emissions counting direct and indirect agricultural emissions), can however contribute to both climate change mitigation and adaptation. The main mitigation potential lies in the capacity of agricultural soils to sequester CO2 through building organic matter. This potential can be realized by employing sustainable agricultural practices, such as those commonly found within organic farming systems. Examples of these practices are the use of organic fertilizers and crop rotations including legumes leys and cover crops. Mitigation is also achieved in organic agriculture through the avoidance of open biomass burning and the avoidance of synthetic fertilizers and the related production emissions from fossil fuels. Common organic practices also contribute to adaptation. Building soil organic matter increases water retention capacity, and creates more stabile, fertile soils, thus reducing vulnerability to drought, extreme precipitation events, floods and water logging. Adaptation is further supported by increased agro-ecosystem diversity of organic farms, due to reduced nitrogen inputs and the absence of chemical pesticides. The high diversity together with the lower input costs of organic agriculture is key in reducing production risks associated with extreme weather events. All these advantageous practices are not exclusive to organic agriculture. However, they are core parts of the organic production system, in contrast to most non-organic agriculture, where they play a minor role only. Mitigation in agriculture cannot be restricted to the agricultural sector alone, though. Consumer behaviour strongly influences agricultural production systems, and thus their mitigation potential. Significant factors are meat consumption and food wastage. Any discussion on mitigation climate change in agriculture needs to address the entire food chain and needs to be linked to general sustainable development strategies. The main challenges to climate change mitigation and adaptation in organic agriculture and agriculture in general concern a)the understanding of some of the basic processes, such as the interaction of N2O emissions and soil carbon sequestration, contributions of roots to soil carbon sequestration and the life-cycle emissions of organic fertilizers such as compost; b) approaches for emissions accounting that adequately represent agricultural production systems with multiple and diverse outputs and that also encompass ecosystem services; c) the identification and implementation of most adequate policy frameworks for supporting mitigation and adaptation in agriculture, i.e: not putting systemic approaches at a disadvantage due to difficulties in the quantification of emissions, and in their allocation to single products; d) how to assure that the current focus on mitigation does not lead to neglect of the other sustainability aspects of agriculture, such as pesticide loads, eutrophication, acidification or soil erosion and e) the question how to address consumer behaviour and how to utilize the mitigation potential of changes in consumption patterns

Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development

<p>Background: Plasmodium falciparum contains three genes encoding potential glutamate dehydrogenases. The protein encoded by gdha has previously been biochemically and structurally characterized. It was suggested that it is important for the supply of reducing equivalents during intra-erythrocytic development of Plasmodium and, therefore, a suitable drug target.</p> <p>Methods: The gene encoding the NADP(H)-dependent GDHa has been disrupted by reverse genetics in P. falciparum and the effect on the antioxidant and metabolic capacities of the resulting mutant parasites was investigated.</p> <p>Results: No growth defect under low and elevated oxygen tension, no up-or down-regulation of a number of antioxidant and NADP(H)-generating proteins or mRNAs and no increased levels of GSH were detected in the D10(Delta gdha) parasite lines. Further, the fate of the carbon skeleton of [(13)C] labelled glutamine was assessed by metabolomic studies, revealing no differences in the labelling of a-ketoglutarate and other TCA pathway intermediates between wild type and mutant parasites.</p> <p>Conclusions: First, the data support the conclusion that D10(Delta gdha) parasites are not experiencing enhanced oxidative stress and that GDHa function may not be the provision of NADP(H) for reductive reactions. Second, the results imply that the cytosolic, NADP(H)-dependent GDHa protein is not involved in the oxidative deamination of glutamate but that the protein may play a role in ammonia assimilation as has been described for other NADP(H)dependent GDH from plants and fungi. The lack of an obvious phenotype in the absence of GDHa may point to a regulatory role of the protein providing glutamate (as nitrogen storage molecule) in situations where the parasites experience a limiting supply of carbon sources and, therefore, under in vitro conditions the enzyme is unlikely to be of significant importance. The data imply that the protein is not a suitable target for future drug development against intra-erythrocytic parasite development.</p&gt

Deep ALMA imaging of the merger NGC1614 - Is CO tracing a massive inflow of non-starforming gas?

Observations of the molecular gas over scales of 0.5 to several kpc provide crucial information on how gas moves through galaxies, especially in mergers and interacting systems, where it ultimately reaches the galaxy center, accumulates, and feeds nuclear activity. Studying the processes involved in the gas transport is an important step forward to understand galaxy evolution. 12CO, 13CO and C18O1-0 high-sensitivity ALMA observations were used to assess properties of the large-scale molecular gas reservoir and its connection to the circumnuclear molecular ring in NGC1614. The role of excitation and abundances were studied in this context. Spatial distributions of the 12CO and 13CO emission show significant differences. 12CO traces the large-scale molecular gas reservoir, associated with a dust lane that harbors infalling gas. 13CO emission is - for the first time - detected in the large-scale dust lane. Its emission peaks between dust lane and circumnuclear molecular ring. A 12CO-to-13CO1-0 intensity ratio map shows high values in the ring region (~30) typical for the centers of luminous galaxy mergers and even more extreme values in the dust lane (>45). This drop in ratio is consistent with molecular gas in the dust lane being in a diffuse, unbound state while being funneled towards the nucleus. We find a high 16O-to-18O abundance ratio in the starburst region (>900), typical of quiescent disk gas - by now, the starburst is expected to have enriched the nuclear ISM in 18O relative to 16O. The massive inflow of gas may be partially responsible for the low 18O/16O abundance since it will dilute the starburst enrichment with unprocessed gas from greater radii. The 12CO-to-13CO abundance is consistent with this scenario. It suggests that the nucleus of NGC1614 is in a transient phase of evolution where starburst and nuclear growth are fuelled by returning gas from the minor merger event.Comment: 10 pages, 9 figures, accepted for publication in A&

The effect of cattle slurry in combination with nitrate and the nitrification inhibitor dicyandiamide on in situ nitrous oxide and dinitrogen emissions

peer-reviewedA field study was conducted to determine the effect of the nitrification inhibitor dicyandiamide (DCD) on N2O and N2 emissions after cattle slurry (CS) application in the presence of nitrate (NO3) fertiliser on seven different occasions (between March 2009 and March 2011). N2O emissions from CS in the presence of NO3 fertiliser were very high (0.4–8.7% of applied N) over a 20-day period, under mild moist conditions. Emissions were significantly larger from the CS treatment compared to an NH4+-N source, supplying the same rate of N as in the slurry. This study supports the view that organic fertilisers should not be applied at the same time as nitrate-based fertilisers, as significant increases in N2O emissions occur. The average N2O mole fraction (N2O/(N2O + N2)) over all seven application dates was 0.34 for CSNO3 compared to 0.24 for the NH4ClNO3 treatment, indicating the dominance of N2 emissions. The rate of nitrification in CSNO3 was slower than in NH4ClNO3, and DCD was found to be an effective nitrification inhibitor in both treatments. However, as N2O emissions were found to be predominantly associated with the NO3 pool, the effect of DCD in lowering N2O emissions is limited in the presence of a NO3 fertiliser. To obtain the maximum cost-benefit of DCD in lowering N2O emissions, under mild moist conditions, it should not be applied to a nitrate containing fertiliser (e.g. ammonium nitrate or calcium ammonium nitrate), and therefore the application of DCD should be restricted to ammonium-based organic or synthetic fertilisers.This research was funded by the Irish National Development Plan, through the Research Stimulus Fund (RSF 07 519), administered by the Irish Department of Agriculture, Food and the Marine

Mortality Model for a Perennial Grass in Australian Semi-Arid Wooded Grasslands Grazed by Sheep

Grazing of sheep in marginal semi-arid environments is risky because grazing appears to predispose grass plants, especially palatable species, to sudden death (Hodgkinson, 1994; 1995). These early observations were based on a preliminary analysis of perennial grass survival in a single drought and supported the concept of tactical grazing proposed by Westoby et al. (1989) as a preferred management. Later this idea was developed by suggesting the existence of critical thresholds for perennial grass survival, which when crossed, collapses grass populations (Hodgkinson, 1994). Here we examine the relationship between mortality of a palatable perennial grass, Thyridolepis mitchelliana, and a number of variables measured during a 10-year period

LSST optical beam simulator

We describe a camera beam simulator for the LSST which is capable of illuminating a 60mm field at f/1.2 with realistic astronomical scenes, enabling studies of CCD astrometric and photometric performance. The goal is to fully simulate LSST observing, in order to characterize charge transport and other features in the thick fully depleted CCDs and to probe low level systematics under realistic conditions. The automated system simulates the centrally obscured LSST beam and sky scenes, including the spectral shape of the night sky. The doubly telecentric design uses a nearly unit magnification design consisting of a spherical mirror, three BK7 lenses, and one beam-splitter window. To achieve the relatively large field the beam-splitter window is used twice. The motivation for this LSST beam test facility was driven by the need to fully characterize a new generation of thick fully-depleted CCDs, and assess their suitability for the broad range of science which is planned for LSST. Due to the fast beam illumination and the thick silicon design [each pixel is 10 microns wide and over 100 microns deep] at long wavelengths there can be effects of photon transport and charge transport in the high purity silicon. The focal surface covers a field more than sufficient for a 40x40 mm LSST CCD. Delivered optical quality meets design goals, with 50% energy within a 5 micron circle. The tests of CCD performance are briefly described.Comment: 9 pages, 9 figure