Reconstructive surgery for oral cavity cancer

Treatment of patients with advanced oral cavity cancer remains challenging

Organ-preserving surgery using endografts from superelastic titanium-nickelid-based alloy for patients with laryngeal cancer

Our study has demonstrated feasibility of performing larynx preservation surgeries in patients with recurrent laryngeal cancer after failure of radiotherapy. The technique of combined laryngeal reconstruction with endografts from superelastic titanium-nickelid-based alloy results in improvement of life quality by preserving laryngeal functions.</jats:p

Reconstructive surgery for oral cavity cancer

Treatment of patients with advanced oral cavity cancer remains challenging

Sparing surgery with the use of TiNi-based endografts in larynx cancer patients

Background and Objective

Sparing surgery with the use of TiNi-based endografts in larynx cancer patients

Background and Objective

Possibilities traditional and liquid-based cytology combined with immunocytochemical detection of some molecular markers in the preoperative diagnosis of well-differentiated thyroid cancer

Aim. To establish the diagnostic value of liquid and traditional cytological diagnosis with immunocytochemical (ICC) detection proteins (galectin-3, nucleophosmin, Ki-67) in the preoperative diagnosis of well-differentiated thyroid cancer and analysis of the effect of the autoimmune process in the thyroid gland in the diagnostic accuracy. Materials and methods. The traditional liquid-based cytology was performed on 107 samples and immunocytochemistry performed on 56 samples with histological findings: colloid goiter in 24 cases, 4 cases of Hashimoto’s thyroiditis, 4 cases of follicular adenoma, 22 cases of papillary cancer. Results. The results of a comparison of cytological and histological findings. The results of studies of diagnostic accuracy expression of galectin-3, nucleophosmin, Ki-67 for the diagnosis of thyroid cancer. A formula was developed to help determine the presence of malignancy in thyroid with high accuracy. Conclusion. The diagnostic accuracy of the method of liquid-based cytology is higher than the traditional method of cytology. ICC expression of Ki-67 method has 81.8% of sensitivity and 100% of specificity for the preoperative diagnosis of thyroid cancer. Conjoint definition HS Ki-67 and liquid-based cytology increases the sensitivity and specificity of the diagnosis of well-differentiated thyroid cancer preoperative to 100%. There no detected relations between the expression of galectin-3, NFM, Ki-67 and the presence an autoimmune process in the thyroid