Phytochemical Screening and Blood Glucose Level Effects of Bhee Fruit Extract (Melastoma sp) on Diabetic Mice

Diabetes is a non-communicable disease among the highest causes of death worldwide, including in Indonesia. Factors that cause diabetes include pancreatic β-cell damage, genetic factors, and an unhealthy lifestyle. Diabetes is characterized by high blood glucose levels (hyperglycemia) beyond normal limits. Hyperglycaemia can be treated using synthetic chemical drugs or insulin therapy, which has adverse long-term effects. The community believes herbal medicine is an alternative diabetes treatment. Melastoma sp is a plant that has the potential as an antidiabetic agent. This study aimed to determine the effectiveness of ethanol extract of Bhee fruit (Melastoma sp) on blood glucose levels of diabetic mice. This study is a laboratory experiment using laboratory animals. The mice were divided into seven treatment groups with three replicates: KN (normal control), KP (treatment control), KD (diabetes control), KO (drug control), P1 (treatment dose of 100 mg/kgBB extract), P2 (treatment dose of 200 mg/kgBB extract), and P3 (treatment dose of 400 mg/kgBB extract). The study's results, the administration of doses of ethanol extract of the fruit 100, 200, and 300 mg /kgBB for 14 days reduced glucose levels in diabetic mice. However, they could not exceed the ability metformin at a dose of 500 mg/kgBB

Pengaruh Ekstrak Air Selada Laut (Ulva Lactuca) Terhadap Berat Badan Pada Tikus Diabetes

Unhealthy lifestyle is one of the leading causes to Diabetes Mellitus (DM) disorder which is characterized by beyond normal limits of high blood glucose levels. Seawed (Ulva lactuca) is one type of natural material that is potentially to be anti-DM. Unfortunately, it is not familiar yet to the wider community, especially in Aceh. The purpose of this study was to determine the effect of giving Ulva lactuca water extract to the body weight of DM rats. The research is an experimental completely randomized design (CRD). Rats were grouped into 5 treatments with three replications, namely: KN = normal control (only fed and distilled water), Ka = STZ control (rat induced STZ 65 mg), P1 = rat DM + extract dose 200 mg / KgBB, P2 = DM rats + extract dose 300 mg / KgBB, P3 = DM rats + extract dose 400 mg / KgBB. Measurement of body weight (BB) of rats was carried out for 28 days. Data analysis was performed statistically (ANOVA). The results showed that the water extract of Ulva lactuca affected the changes in body weight of DM rats. The treatment groups of P1, P2 and P3 gained weight after being given Ulva lactuca water extract. The highest percentage of weight increase was found in the P2 and P3 treatment groups.   Keywords: Diabetes Mellitus, Weight, Sea Lettuce (Ulva lactuca)Pola hidup tidak sehat merupakan salah satu penyebab munculnya penyakit Diabetes Mellitus (DM) yang ditandai oleh tingginya kadar glukosa darah melebihi batas normal. Selada laut (Ulva lactuca) merupakan  salah satu  jenis bahan alam yang berpotensi sebagai anti DM namun belum dikenal oleh masyarakat luas terutama di Aceh. Tujuan penelitian ini untuk mengetahui pengaruh pemberian  ekstak air Ulva lactuca terhadap berat badan tikus DM. Penelitian bersifat eksperimen Rancangan Acak Lengkap (RAL). Tikus dikelompokkan menjadi 5 pelakuan dengan tiga kali ulangan,yaitu:  KN= Kontrol normal (hanya diberi pakan dan akuades), Ka= Kontrol STZ (Tikus diinduksi STZ 65 mg), P1= Tikus DM + dosis ektrak 200 mg/KgBB, P2= Tikus DM + dosis ekstrak 300 mg/KgBB,  P3= Tikus DM + dosis ekstrak 400 mg/KgBB. Pengukuran Berat Badan (BB) tikus dilakukan selama 28 hari. Analisis data dilakukan secara statistik (ANOVA). Hasil penelitian menunjukkan bahwa ekstrak air Ulva lactuca berpengaruh terhadap perubahan berat badan tikus DM. Kelompok perlakuan P1, P2 dan P3 mengalami kenaikan berat badan setelah diberi ekstrak air Ulva lactuca. Persentase kenaikan tertinggi terdapat pada kelompok perlakuan P2 dan P3.   Kata Kunci: Diabetes Millitus, Berat, Selada laut (Ulva lactuca

The Effectiveness of Sea Lettuce (Ulva Lactuca) Water Extract from Aceh Waters as an Anti-Obesity

Obesity is a condition of weight excess above average weight. Obesity can happen due to calories continuing into the body without being offset by physical activity. This study aims to determine the effectiveness of the water extract of Ulva Lactuca against weight loss in obese mice. type of research used is laboratory experiments using the design posttest only control group design research. we grouped into 7 groups, namely: normal Control, Positive Control, Treatment Control, P1= the group of obese mice + extract 300 mg/kg, P2= the group of obese mice + extract 400 mg/kg, P3= the group of obese mice + extract 500 mg/kg P4=the group of obese mice + orlistat.The Aqueous Extract of Ulva Lactuca has not been able to lose obese mice for 28 days of treatment. Normal mice in treatment of the Extract did not show changes in body weigh

Food Intake of Overweight and Obesity in Children Aged 7-12 Years at Aceh Barat District

Nutrition problems in Indonesia are already classified as multiple nutritional problems, namely the problem of undernutrition and overweight obesity. In 2010 the prevalence of overweight and obesity in Aceh province was 11.2 percent and in 2013 was 14.8 percent (8.9 percent fat and 5.9 percent very fat) resulting in an increase of 3.6 percent. Food intake is one factor that can cause cause overweight and obesity. This study wanted to analyze the factors of food intake in children aged 7-12 years become the cause of overweight and obesity. This study was an observational analytic study with cross sectional design aimed at assessing relationship of food intake on obesity-related weight status in first-fifth grade elementary school children aged 7-12 years at Kabupaten Aceh Barat. The sample size is 289 students. Determination of child obesity status using Body Mass Index based on Age (IMT/U), that is overweight and obesity if IMT/U>1.0 SD. Data of food intake was obtained through interview using 24-hour food recall form for 3 days. From 289 respondents, 51.90% were overweight and obesity. Factors related to the incidence of overweight and obesity are energy and fat intake (OR = 4.56 and 4.03)

EDUKASI GEMARI (Gemar Makan Ikan) MELALUI METODE ROLE PLAY SERTA PENGOLAHAN IKAN SEBAGAI UPAYA PENINGKATAN GIZI PADA SISWA PESANTREN MODERN YAYASAN BABUL FIKRI KECAMATAN MEUREUBO KABUPATEN ACEH BARAT

Indonesia is a maritime country and produces a lot of fish, but according to BPS data, the average protein consumption, including Indonesian fish consumption, is 64.64 grams per capita a day, while Aceh is only 58.99 grams per capita a day. This service activity aims to educate students at Islamic boarding schools about the importance of fish consumption, invite students to eat processed fish so that it is hoped that they will be able to increase knowledge and change fish consumption behavior. The participants of this activity were 40 students of the Babul Fikri Islamic Boarding School. The method used is the Role Play method and also uses PPT tools about the importance of fish consumption. Educational results obtained an increase in students' knowledge related to fish consumption as seen from the average value of the level of knowledge, namely (2,625-4.725 = 2.1 points), so we can conclude that the love of eating fish education carried out can increase students' knowledge and will be able to change adolescent behavior behavior that is able to overcome the problem of fish consumption. In addition, it was also seen that there was an increase in fish consumption which was better than before education, from 42.5% to 63.5%

Effectiveness of Water Extract of Sea Lettuce (Ulva Lactuca) from Aceh to Reduce Blood Glucose Levels in Diabetic Rats

Diabetes mellitus (DM) is a non-communicable disease characterized by high blood glucose levels caused by damage to the pancreas, which cannot produce insulin. Antidiabetic drugs and insulin injections in the long term have specific side effects, so herbal medicine is considered safer to use. Sea lettuce (Ulva lactuca) is one of the herbal medicines that have the potential as an antidiabetic. Methods: Experimental using a completely randomized design. Rats were divided into five groups with three replicates, namely: Kn = normal control, Ka = STZ control, P1 = DM rats + 200 mg/KgBB extract dose, P2 = DM rats + 300 mg/KgBB extract dose, and P3 = DM rats + 400 mg/KgBB extract dose. The stages of this study began with the preparation of tools and materials, phytochemical tests, the preparation of test animals and testing extracts on test animals, and the measurement of blood glucose levels in rats before and after they were given extracts. Blood glucose levels were measured using a glucometer. Data analysis was performed statistically (ANOVA). The results of the phytochemical tests detected were steroids, saponins, and phenols/tannins, while alkaloids, terpenoids, and flavonoids were not. The most effective blood glucose level measurement result is at a dose of 400 mg/KgBB

The Relationship between Parenting Patterns and Fish Consumption in Elementary School-Age Children in West Aceh District

Seafood is a nutrient-dense food that is needed by children in their infancy. Sea fish is rich in protein, vitamins and minerals as well as omega 3 fatty acids which are very important for the growth of both body cells and brain cells. Several factors are identified as the cause of low fish consumption in Indonesia, among others, the lack of public understanding of nutrition and the benefits of fish consumption for health and intelligence, socio-economy and culture. So that it affects the parenting style of parents in providing food intake to children. The large protein content in fish is expected to be able to improve the nutritional needs of the Indonesian people and the increase in fish consumption is also expected to have an effect on increasing the intelligence of the Indonesian people. The research aimed to determine the relationship between parenting and fish consumption among school-age children in Aceh Barat District. This study was a cross-sectional study. The sample in this study amounted to 173 elementary school age children in grades IV and V. The data was collected by means of direct interviews which included the patterns of upbringing and fish consumption. Data analysis includes univariate and bivariate analysis with independent sample t-test. From 173 children, it was found that 80.3% of children consumed fish well, while only 19.7% of children with poor fish consumption. Maternal parenting affects children's fish consumption with an OR = 12.865 (95% CI 4.933-3.552) so that maternal parenting has a 12.86 times chance of influencing fish consumption in children

Mother’s Perception of Obesity with Overweight and Obesity in Children Aged 7-12 Years at Kabupaten Aceh Barat

Nutrition problems in Indonesia are already classified as multiple nutritional problems, not just nutritional deficiency problems, but the prevalence of overweight and obesity also increases. In 2010 the prevalence of overweight and obesity in Aceh province was 11.2 percent and in 2013 was 14.8 percent resulting in an increase of 3.6 percent. Mother's perception is one factot that can cause cause overweight and obesity. This study wanted to analyze the factors This study wanted to analyze the factors of mother perception in children aged 7-12 years become the cause of overweight and obesity. This study was an observational analytic study with cross sectional design aimed at assessing relationship of mother's perception on obesity-related weight status in first-fifth grade elementary school children aged 7-12 years at Kabupaten Aceh Barat. The sample size is 289 students. Determination of child obesity status using Body Mass Index based on Age (IMT/U), that is overweight and obesity if IMT/U>1.0 SD. Data of mother's perception were obtained through questionnaire. There are 51.90% of 289 respondents who had overweight and obesity. There is no relationship between mother perception of obesity with overweight and obesity (p=0.426). But it is different when viewed specifically about the mother's perception related to the child's weight status. Wrong mother's perception of child's weight status has a risk of 4.15 times greater than the right one. There is a correlation between mother’s perception of child's weight status with overweight and obesity