Optimal Design of Box Composting Plant; A Case Study Of Pakistan

In this research, a feasible design framework has been developed in order to design a box composting facility. Box composting technique is potentially a sustainable method to deal with solid waste management issues. Three different existing composting facilities in the different provinces of Pakistan have been studied to investigate the duration of composting under different weather conditions and therefore baseline durations for composting against the varying climate of different regions in Pakistan have been established. The data validated that the duration of the composting decreases with the increase in temperature. Moreover, a design framework that incorporates the weather conditions, as well as the density of waste, has been presented to calculate the sizes of composting and maturing boxes. A numerical design example has been successfully solved by assuming the data which proved the feasibility of the developed framework to design the compost facility as per any given requirements

Load Frequency Control (LFC) Strategies in Renewable Energy‐Based Hybrid Power Systems:A Review

The hybrid power system is a combination of renewable energy power plants and conventional energy power plants. This integration causes power quality issues including poor settling times and higher transient contents. The main issue of such interconnection is the frequency variations caused in the hybrid power system. Load Frequency Controller (LFC) design ensures the reliable and efficient operation of the power system. The main function of LFC is to maintain the system frequency within safe limits, hence keeping power at a specific range. An LFC should be supported with modern and intelligent control structures for providing the adequate power to the system. This paper presents a comprehensive review of several LFC structures in a diverse configuration of a power system. First of all, an overview of a renewable energy-based power system is provided with a need for the development of LFC. The basic operation was studied in single-area, multi-area and multi-stage power system configurations. Types of controllers developed on different techniques studied with an overview of different control techniques were utilized. The comparative analysis of various controllers and strategies was performed graphically. The future scope of work provided lists the potential areas for conducting further research. Finally, the paper concludes by emphasizing the need for better LFC design in complex power system environments

Scheduling and Sizing of Campus Microgrid Considering Demand Response and Economic Analysis

Current energy systems face multiple problems related to inflation in energy prices, reduction of fossil fuels, and greenhouse gas emissions which are disturbing the comfort zone of energy consumers and the affordability of power for large commercial customers. These kinds of problems can be alleviated with the help of optimal planning of demand response policies and with distributed generators in the distribution system. The objective of this article is to give a strategic proposition of an energy management system for a campus microgrid (µG) to minimize the operating costs and to increase the self-consuming energy of the green distributed generators (DGs). To this end, a real-time based campus is considered that currently takes provision of its loads from the utility grid only. According to the proposed given scenario, it will contain solar panels and a wind turbine as non-dispatchable DGs while a diesel generator is considered as a dispatchable DG. It also incorporates an energy storage system with optimal sizing of BESS to tackle the multiple disturbances that arise from solar radiation. The resultant problem of linear mathematics was simulated and plotted in MATLAB with mixed-integer linear programming. Simulation results show that the proposed given model of energy management (EMS) minimizes the grid electricity costs by 668.8 CC/day ($) which is 36.6% of savings for the campus microgrid. The economic prognosis for the campus to give an optimum result for the UET Taxila, Campus was also analyzed. The general effect of a medium-sized solar PV installation on carbon emissions and energy consumption costs was also determined. The substantial environmental and economic benefits compared to the present situation have prompted the campus owners to invest in the DGs and to install large-scale energy storage

Development and validation of a chromatographic method for quantification of rasagiline in human plasma

Purpose: To develop a sensitive, reliable and cost-effective bioanalytical method for the pharmacokinetic analysis of rasagiline in human plasma.Method: Rasagiline was extracted by liquid-liquid extraction method and analyzed by reversed-phase high performance liquid chromatography (HPLC) using a mixture of ammonium acetate (pH 5.8) and acetonitrile (55:45, v/v) as mobile phase at a flow rate of 1 mL/min. The separation was performed on a Lichrosphere reverse-phase (RP) C18 column (250 x 4.6 mm, 5 μm particle size) at ambient temperature and rasagiline was detected at a wavelength of 265 nm by ultra-violet UV detection. The method was validated according to European Medicine Agency (EMA) guidelines. Results: The developed method was linear over a concentration range of 0.5 - 20 μg/ml with r2 ≥ 0.999 in human plasma. Run time was 10 min with rasagiline peak appearing at 7 min with no interference. Relative recovery and relative standard deviation (RSD) for accuracy and precision were within the acceptable limits prescribed in EMA guidelines. Rasagiline remained stable in human plasma for 24 h at room temperature, after three freeze and thaw cycles and also for 3 months at -20 °C.Conclusion: A simple and reliable method has been successfully developed and validated for the determination of rasagiline concentration in human plasma.Keywords: Rasagiline, Pharmacokinetics, Validation, Parkinson's diseas

An energy management system of campus microgrids:State-of-the-art and future challenges

The multiple uncertainties in a microgrid, such as limited photovoltaic generations, ups and downs in the market price, and controlling different loads, are challenging points in managing campus energy with multiple microgrid systems and are a hot topic of research in the current era. Microgrids deployed at multiple campuses can be successfully operated with an exemplary energy management system (EMS) to address these challenges, offering several solutions to minimize the greenhouse gas (GHG) emissions, maintenance costs, and peak load demands of the microgrid infrastructure. This literature survey presents a comparative analysis of multiple campus microgrids’ energy management at different universities in different locations, and it also studies different approaches to managing their peak demand and achieving the maximum output power for campus microgrids. In this paper, the analysis is also focused on managing and addressing the uncertain nature of renewable energies, considering the storage technologies implemented on various campuses. A comparative analysis was also considered for the energy management of campus microgrids, which were investigated with multiple optimization techniques, simulation tools, and different types of energy storage technologies. Finally, the challenges for future research are highlighted, considering campus microgrids’ importance globally. Moreover, this paper is expected to open innovative paths in the future for new researchers working in the domain of campus microgrids

The Chemical Composition and Health-Promoting Effects of the Grewia Species—A Systematic Review and Meta-Analysis

Globally grown and organoleptically appreciated Grewia species are known as sources of bioactive compounds that avert the risk of communicable and non-communicable diseases. Therefore, in recent years, the genus Grewia has attracted increasing scientific attention. This is the first systematic review which focusses primarily on the nutritional composition, phytochemical profile, pharmacological properties, and disease preventative role of Grewia species. The literature published from 1975 to 2021 was searched to retrieve relevant articles from databases such as Google Scholar, Scopus, PubMed, and Web of Science. Two independent reviewers carried out the screening, selection of articles, and data extraction. Of 815 references, 56 met our inclusion criteria. G. asiatica and G. optiva were the most frequently studied species. We found 167 chemical compounds from 12 Grewia species, allocated to 21 categories. Flavonoids represented 41.31% of the reported bioactive compounds, followed by protein and amino acids (10.7%), fats and fatty acids (9.58%), ash and minerals (6.58%), and non-flavonoid polyphenols (5.96%). Crude extracts, enriched with bioactive compounds, and isolated compounds from the Grewia species show antioxidant, anticancer, anti-inflammatory, antidiabetic, hepatoprotective/radioprotective, immunomodulatory, and sedative hypnotic potential. Moreover, antimicrobial properties, improvement in learning and memory deficits, and effectiveness against neurodegenerative ailments are also described within the reviewed article. Nowadays, the side effects of some synthetic drugs and therapies, and bottlenecks in the drug development pathway have directed the attention of researchers and pharmaceutical industries towards the development of new products that are safe, cost-effective, and readily available. However, the application of the Grewia species in pharmaceutical industries is still limited

Health and Safety Assessment in Lakhra Coal Mines and Its Mitigation Measures

oai:ojs.localhost:article/200The coal mine excavation, transportation and coal cutting process are involved in hazards and risks that can result in fatalities, injuries and diseases, if these are not properly managed. This study has been undertaken for assessment of the safety and health issues amongst the mines workers. Convenience sampling technique was exercised upon 97 mine workers and interviewed with the help of set questionnaire. Personnel protection to workplace environment was monitored by using physical observation and scientific analysis. All parameters were measured against national and international protocols pertaining to labor law at coal mines. It has been determined that very high risk was persisting while mine excavation, coal cutting and transportation processes. Previous record of last five years was suggesting that 04 deaths happened due to roof fall, 03 fatalities occurred through suffocation by inhaling toxic gases, one causality happened via rope haulage pulley, and also one death due to stone fall down from mine shaft. 121 workers injured in different kinds of accidents within five years. It has been learnt from in-depth analysis that maximum of health risk and subsequent health damages are triggering due to lack of awareness, non-compliance of labor as well as mines laws. Thus, it is recommended that government should not allow coal mining contractors and companies, those which are failing in compliance with the suggested standards

Phytochemical Profile, Biological Properties, and Food Applications of the Medicinal Plant Syzygium cumini

Syzygium cumini, locally known as Jamun in Asia, is a fruit-bearing crop belonging to the Myrtaceae family. This study aims to summarize the most recent literature related to botany, traditional applications, phytochemical ingredients, pharmacological activities, nutrition, and potential food applications of S. cumini. Traditionally, S. cumini has been utilized to combat diabetes and dysentery, and it is given to females with a history of abortions. Anatomical parts of S. cumini exhibit therapeutic potentials including antioxidant, anti-inflammatory, analgesic, antipyretic, antimalarial, anticancer, and antidiabetic activities attributed to the presence of various primary and secondary metabolites such as carbohydrates, proteins, amino acids, alkaloids, flavonoids (i.e., quercetin, myricetin, kaempferol), phenolic acids (gallic acid, caffeic acid, ellagic acid) and anthocyanins (delphinidin-3,5-O-diglucoside, petunidin-3,5-O-diglucoside, malvidin-3,5-O-diglucoside). Different fruit parts of S. cumini have been employed to enhance the nutritional and overall quality of jams, jellies, wines, and fermented products. Today, S. cumini is also used in edible films. So, we believe that S. cumini’s anatomical parts, extracts, and isolated compounds can be used in the food industry with applications in food packaging and as food additives. Future research should focus on the isolation and purification of compounds from S. cumini to treat various disorders. More importantly, clinical trials are required to develop low-cost medications with a low therapeutic inde

Structural performance of waste plastic bottles modified asphalt: A review

The usage of plastic materials in our daily life is increasing day by day. These plastic materials are somehow beneficial for us, but the disposal of waste plastic materials has become a serious problem. The use of plastic not only enhances road construction but also helps extend the life of roads and improves the environment. Waste plastics use in roads increases durability and also reduces water retention. This research reviews the use of waste plastics in asphalt pavement. In this study, the properties such as Marshall stability, flow, resilient modulus, fatigue, etc., are studied to boost the usage of waste plastic in asphalt pavements. It is concluded that with the use of waste plastic in asphalt pavement, the quality of roads will be enhanced, and it will also be very beneficial for our environment. The other major advantage is that it will be very cost-effective for underdeveloped countries.Web of Science121art. no. 1