Impact of Stress on Job Satisfaction of Managerial Employees working in Commercial Banks: a case study of District Ghotki Sindh

Job stress is well thought-out as the injurious physical and mental response that occurs when there is a meager match between work demands and abilities, resources or needs of the employee This  research  was  carried out  to  compute  the  impact  of  job  pressure  on the degree of  job  satisfaction  of managerial employees working in Domestic Commercial Banks. Job satisfaction describes how comfortable an individual is with own job. A self develop research model was experienced where job stress is stated as the independent variable.  All the branches of domestic commercial banks located in ghotki district were investigated and it was carried out on a sample of 30 branch managers. A self develop questionnaire was used to collect data. . Researcher found that there is a high degree of job stress among branch managers of private commercial banks. Findings revealed that women managers have a higher degree of job stress than male managers. Study concluded that job stress is significantly correlated with job satisfaction. Key Words:  job stress, Domestic Commercial Banks, Job Satisfaction

Post tuberculosis radiological sequelae in patients treated for pulmonary and pleural tuberculosis at a tertiary center in Pakistan

Treating tuberculosis (TB) is not the end of the disease because of the wide spectrum of post TB sequelae associated with the disease. There is insufficient data on post TB radiological sequelae. The aim of this study is to evaluate the post TB radiological sequelae on chest x-rays in patients who had completed the treatment for pulmonary and pleural TB at a tertiary care hospital of a high TB burden country. This is a retrospective cross-sectional study conducted on patients treated for pulmonary and pleural TB. Adult patients (18 years or above) with a clinical or microbiological diagnosis of pulmonary or pleural TB were included. Patients were classified on the basis of site of TB into pulmonary and pleural TB. Post-treatment radiological sequelae on chest x-ray were evaluated and divided into three main types i.e. fibrosis, bronchiectasis and pleural thickening. During the study period a total of 321 patients were included with a mean age of 44(SD±19) years. Only 17.13% (n=55) patients had normal chest x-rays at the end of treatment and 82.87% (n=266) patients had post-TB radiological sequelae with fibrosis being the most common followed by pleural thickening. The post TB radiological sequelae were high in patients who had diabetes mellitus (78.94%), AFB smear-positive (90.19%), AFB culture-positive (89.84%), Xpert MTB/Rif positive (88.40%) and with drug-resistant TB (100%). As a clinician, one should be aware of all the post TB sequelae so that early diagnosis and management can be facilitated

Sistem Informasi Pemasaran Paket Tour Koperasi Karya Wisata Senggigi Berbasis Web

Sektor pariwisata sebagai kegiatan perekonomian telah menjadi andalan potensial dan prioritas pengembangan bagi sejumlah Negara.Terlebih bagi negara berkembang seperti Indonesia yang memiliki potensi wilayah yang luas dengan daya tarik wisata yang cukup besar. Koperasi Karya Wisata Senggigi (KOPKARWIS) adalah sebuah koperasi yang bergerak dalam bidang pariwisata dengan menyediakan jasa Tour and Travel di daerah Senggigi. Masalah yang di hadapai Koperasi Karya Wisata Senggigi adalah tentang pemasaran paket-paket tour yang mereka tawarkan dan menghubungi driver/guide. Adapun tujuan dari penelitian ini, yaitu Membangun sebuah Sistem Informasi Pemasaran Paket Tour Koperasi KARYA WISATA Senggigi Berbasis Web. Perancangan dan Pembuatan Aplikasi menggunakan metodologi Waterfall, yaitu metode mengembangan perangkat lunak yang diawali dengan menganalisa kebutuhan perusahaan, membuat merancang, membangun aplikasi dengan tools, dan melakukan ujicoba pada pengguna. Hasil yang dicapai yaitu berupa Sistem Informasi Pemasaran Paket Tour Koperasi KARYA WISATA Senggigi yang dapat membantu operasional koperasi. Berdasarkan hasil quisioner yang diberikan kepada pengguna, aplikasi yang dibangun dapat dipahami dan mudah digunakan dalam memberikan informasi pemesanan serta meningkatkan pemesanan dan sesuai dengan kebutuhan pengguna. Aplikasi Sistem Informasi Pemasaran Paket Tour Koperasi KARYA WISATA Senggigi Berbasis Web telah berhasil dibangun

Effects of Magnesium Sulfate Therapy on GCS Scores in Patients with Severe Traumatic Brain Injury

Objective:  Traumatic brain injury (TBI) is the number one cause of death under 44 years of age; in spite of this fact, there is no standard available pharmacological agent for the treatment of brain injury. We evaluated the effectiveness of magnesium sulfate treatment for the management and outcome of TBI. Material and Methods:  The prospective cases (n = 60) of TBI were included with non-probability consecutive sampling. They received standard protocol treatment for TBI and magnesium sulfate as an add on therapy. GCS was noted on two occasions, at the time of admission and on the 3rd day. T-test was used to compare the results and for identification of significance/insignificance results. Results:  Mean age of the patients was 37.12 ± 13.25 years. Majority were male (68.3%), while females were 31.7%. Mean duration of an elapsed post traumatic brain injury was 5.06 ± 2.32 hours. Mean GCS before magnesium sulfate treatment (on admission) was 5.46 ± 1.521; mean Glasgow coma (GCS) after magnesium sulfate treatment (on 3rd day) was 8.03 ± 2.56. There existed a significant difference between the GCS scores at the time of admission and on 3rd day (p value < 0.0001). Mean GCS was 7.69 ± 2.55 in age < 30 years and it was 8.29 ± 2.57 in age > 30 years, but this difference was not statistically significant.  Conclusion:  A significant improvement was found in the GCS after magnesium sulfate therapy in patients with TBI

An efficient synthesis and spectroscopic characterization of Schiff bases containing 9,10-anthracenedione moiety

A new method has been developed for the synthesis of novel Schiff bases containg anthraquinone moiety using dodeca-Tungstosilicic acid/P2O5 under solvent free conditions at room temperature. The reaction was completed in 1-3 minutes with excellent yields. This method was found to be more efficient, easy and hazardous free for the synthesis of azomethines. The development of these type of methadologies in synthetic chemistry may contribute to green chemistry. The structures of synthesized novel Schiff bases was elucidated using 1H-NMR, 13C-NMR, LCMS, FTIR and CHN analysis

Frequency of translocation t(11;22)(q24;q12) using fluorescence in situ hybridization (FISH) in histologically and immunohistochemically diagnosed cases of ewing\u27s sarcoma

Introduction: Ewing sarcoma (ES) family of tumors is one of the most common groups of malignancies arising in children, adolescents, and young adults. Although characteristic histology with immunohistochemical expression of CD99 and FLI1 after exclusion of other small round blue cell tumors is considered diagnostic of ES, frequency of typical ES translocation, i.e., t(11;22)(q24;q12) is not known in our population. Therefore, in this study, we aimed to evaluate the frequency of this translocation in histologically and immunohistochemically diagnosed cases of ES along with its association with other pathological parameters.Methods: A total of 43 morphologically and immunohistochemically diagnosed cases of ES were included in the study. Fluorescence in situ hybridization (FISH) was performed on representative paraffin blocks to identify t(11;22)(q24;q12) translocation. Association with various clinicopathological characteristics was determined.Results: Mean age of the patients was 18.23±9.57 years. Bone was the most commonly involved site (22; 51.2%) followed by soft tissue (17; 39.5%) and parenchymal organs (4; 9.3%). A total of 88.4% of cases were found to be FISH-positive for t(11;22)(q24;q12). No significant association of translocation positive cases was noted with tumor size or disease-free survival. Similarly, no significant association of tumor size with disease-free survival was found.Conclusions: A significant proportion of cases of histologically diagnosed cases of ES exhibited characteristic t(11;22)(q24;q12). This signifies that histology along with immunohistochemistry is reliable for the diagnosis of this tumor; however, in difficult cases, FISH can be performed to detect characteristic translocation. Moreover, we did not find tumor size to be a significant prognostic indicator of survival in ES

Non-linear control law for articulated serial manipulators: Simulation augmented with hardware implementation

The performance of a robotic arm includes accuracy, repeatability and reliability to accomplish a task. These parameters, in turn, are function of associated control law. Multi-Degree Of Freedom (DOF) robotic arms, because of their inherent highly non-linear dynamics, demand sophisticated control laws. Trivial control strategies fail to cope with disturbances and uncertainties that are common in today's plants. This paper presents the design, simulation and physical implementation of a non-linear control technique Variable Structure Control (VSC) for a 6 DOF arm. Based on the derived dynamic model of the arm and designed control law, simulations have been conducted in MATLAB/Simulink. The controller parameters have been tuned for optimal response. Various desired trajectories characterize the tracking performance of the control law. The simulation results have been then validated by implementing the law on a customdeveloped novel AUTonomous Articulated Robotic Educational Platform (AUTAREP). Coupling effects between various joints of the robot have also been investigated. Results of this research find potential in industrial control of robotic manipulators to perform complex tasks

Evaluation of Antibiotics Pattern of Extended Spectrum Beta-Lactamase Producing Multi-Drug Resistant Pseudomonas aeruginosa

Background: Pseudomonas aeruginosa (Ps. aeruginosa) is considered as an opportunistic pathogen and the leading cause of morbidity and mortality in immunocompromised individuals. Globally, approximately 10-15% of the nosocomial infections are caused by Ps. aeruginosa. The Ps. aeruginosa can acquire resistance against broad-spectrum antibiotics. According to recent studies increased mortality has been observed due to infection with extended-spectrum-beta-lactamase (ESBL) producing Ps. aeruginosa strains. This study was designed to determined antibiogram of ESBL producing multi-drug resistant Ps. aeruginosa in Khyber Pakhtunkhwa.Methods: The clinical confirmed Ps. aeruginosa samples were collected according to the standard protocol, at Khyber Teaching Hospital (KTH), Peshawar. All collected samples were sub- cultured on appropriate culture media. After isolation and identification, the antibiotics susceptibility testing was performed. The detection of ESBL was carried out by the double-disc diffusion method. Carbapenemase-producing bacteria was confirmed by the modified Hodge test. Descriptive analysis was performed for statistical analysis of collected data.Results: A total of one hundred and sixty-two (n=162) Ps. aeruginosa confirmed isolates were collected, in which 59.3% were male and 40.7% were from female patients. The percentages of ESBL and carbapenemase producing Ps. aeruginosa isolates were 5.5% and 23.5%, respectively. The multidrug resistance was observed against 27.2% isolates. Among tested antibiotics highest percentages of resistance was observed against ciprofloxacin (43%) and ceftazidime (39.5%). Conclusion: We observed highest level of drug resistance in Ps. aeruginosa clinical isolates against tested antibiotics and majority of the isolates were Multi-drug resistant (MDR).Keywords: Pseudomonas; Multi-Drug Resistant; Extended Spectrum Beta Lactamases; Antibiotics Susceptibilit