Phytochemicals in prostate cancer: From bioactive molecules to upcoming therapeutic agents

Prostate cancer is a heterogeneous disease, the second deadliest malignancy in men and the most commonly diagnosed cancer among men. Traditional plants have been applied to handle various diseases and to develop new drugs. Medicinal plants are potential sources of natural bioactive compounds that include alkaloids, phenolic compounds, terpenes, and steroids. Many of these naturally-occurring bioactive constituents possess promising chemopreventive properties. In this sense, the aim of the present review is to provide a detailed overview of the role of plant-derived phytochemicals in prostate cancers, including the contribution of plant extracts and its corresponding isolated compounds.This work was supported by CONICYT PIA/APOYO CCTE AFB170007. N. Martins would like to thank the Portuguese Foundation for Science and Technology (FCT–Portugal) for the Strategic project ref. UID/BIM/04293/2013 and “NORTE2020 - Programa Operacional Regional do Norte” (NORTE-01-0145-FEDER-000012) and C. F. Rodrigues for the UID/EQU/00511/2019 Project—Laboratory of Process Engineering, Environment, Biotechnology, and Energy—LEPABE financed by national funds through FCT/MCTES (PIDDAC)

Review of plant health clinics: a recent phenomenon for effective plant pests and diseases diagnosis

Plant health clinic is a mechanism in which farmers are able to access basic plant healthcare and services from relevant authority in relation to infested or suspected infested plants and plant products for diagnostic purposes. Plant health clinic is an integral part of the plant health system which provides early pest diagnostic and advisory services to farmers. In this paper, it can be further defined as a basic plant healthcare rendered to farmers to enhance and improve plant production thereby diagnosing plant pests and diseases with the aim of employing appropriate pest management strategy. In many countries, plant health clinics operators are extension experts, plant doctors, inspectors and scientists within government and NGOs. Extension support in particular is critical in the operation of plant health clinics. The purpose of this paper is to provide a global overview of plant clinic as a recent ways of plant diseases diagnosis. This paper concluded that plant health clinics are valuable tools which need to be adopted by various countries for smallholder farmers to understand more about plant pests and diseases as well as management strategy. To the contrary, many countries are dependent on national diagnostic services as opposed to basic plant healthcare which is more accessible to the smallholders. This review paper further revealed that plant health clinics’ knowledge, awareness, accessibility and satisfaction of the smallholder farmers are very important. Plant clinics may not efficiently and effectively operate in the absence of the aforementioned aspects. Plant clinics were found to be the most efficient way to reach smallholder farmers for advice.

Investigating the strength of linkages of plant health institutional and legislative framework in South Africa

This paper presents existing linkages within the spheres of government on plant health institutional and legislative framework and further identifies the existing limitations and risks on the current existing framework on the plant health system. A survey was conducted in South Africa with the relevant scientists from the National Department of Agriculture, Land Reform and Rural Development (DALRRD) formerly known as the Department of Agriculture, Forestry and Fisheries (DAFF) and Department of Environment, Forestry and Fisheries (DAFF) formerly known as Department of Environmental Affair (DEA) as well as extensionist and agricultural advisors from 7 Provincial Departments of Agriculture (PDAs). The sample size of the study was 60 government officials from both the national and provincial departments of agriculture. A semi-structured questionnaire was used to collect the data. The data were analysed statistically using the one-way frequency and Spearman’s Rank correlation coefficients. This paper revealed that there were no formal linkages between the relevant national government and PDAs in terms of legislative and policy prescripts on plant health issues. The study further revealed that there is a need to establish a plant health unit to coordinate plant health matters from the National Plant Protection Organisation of South Africa. On the aspect of biosecurity legislative framework affecting food production and security as well as trade, the study found that there is no cross-referencing amongst relevant legislation; therefore, there is a need for harmonisation of relevant legislation