2 research outputs found
Alterations in the coagulation markers did not showdifferences with the severity of COVIDâ19 in Peruvianpatients: A crossâsectional singleâcenter study
Background and Aims:COVIDâ19 is a pandemic disease that can lead to alteredlung function, systemic inflammatory events, and altered coagulation. During severestages of the disease, changes in coagulation homeostasis increase, leading tothrombosis, and increased risk of death. In this crossâsectional study, we aimedto assess coagulation markers by COVIDâ19 severity in Peruvian adults.Methods:During the second wave of infections, we included 186 adults diagnosedwith COVIDâ19 (mean age 53.3 ± 16.3 years). Patients were divided into mild,moderate, and severe stages of COVIDâ19, and coagulation markers includedprothrombin time (PT), activated partial prothrombin time (aPTT), fibrinogen,Dâdimer, and platelet count.Results:Of the total, 120 (64.5%) were males and 39 (21%) were in the intensivecare unit. We determine 104 (55.9%), 43 (24.7%), and 36 (19.4%) patients in mild,moderate, and severe stages of COVIDâ19, respectively. In the severe stage ofCOVIDâ19, patients had an average concentration of PT, aPTT, fibrinogen,Dâdimer,and platelets of 13.2 ± 0.9 s, 28.9 ± 4.3 s, 679.4 ± 185.1 mg/dL, 1.9 ± 3.1 ÎŒg/mL, and272.8 ± 88.9 cel/10 mm,3respectively. We found no differences in the concentra-tion of each marker according to severity (p< 0.05). Patients with severe COVIDâ19had altered the aPTT, fibrinogen,Dâdimer, and PT in 31 (57.4%), 48 (88.9%), 37(68.5%), and 15 (27.8%) cases, respectively.Conclusions:Our results showed that although there is an alteration in coagulationmarkers, mainly fibrinogen andDâfiber, there are no differences in concentrationaccording to the severity of COVIDâ19
RevisiĂłn del sistema de vigilancia de lesiones y enfermedades durante juegos multideportivos
El objetivo de este estudio fuer presentar al Sistema de Vigilancia de Lesiones y Enfermedades (SVLE) del ComitĂ©OlĂmpico Internacional (COI) diseñado para eventos multideportivos como un insumo para la planificaciĂłn de los recursosnecesarios para competencias deportivas. Desarrollamos una revisiĂłn sistemĂĄtica siguiendo la guĂa PRISMA considerandocomo criterio de inclusiĂłn los eventos multideportivos con implementaciĂłn de la SVLE del COI. La bĂșsqueda fue realizadaen los principales buscadores cientĂficos (PubMed, Scopus, Scielo, ScientDirect, LILACS, y Latindex), en servidores pĂșblicosde pre-publicaciones (bioRxiv, SocArXiv, medRxiv y Preprints) y en metabuscadores (Google Scholar y Yahoo!). En laselecciĂłn inicial se obtuvieron 367 estudios, incluyĂ©ndose 19 estudios para su anĂĄlisis, donde solo 4 fueron deportes unitarioscomo fĂștbol, atletismo y balonmano. El SVLE del COI se ha usado inicialmente a gran escala en los Juegos OlĂmpicos deBeijing 2008 en 7 idiomas, al dĂa de hoy mĂĄs de 56,063 atletas en 19 eventos deportivos. En SudamĂ©rica este sistema fueempleado en el I Juegos Deportivos Nacionales de Chile, los Juegos OlĂmpicos de Verano y los Juegos OlĂmpicos Rio 2016,y en los Juegos Panamericanos Lima 2019. Esta revisiĂłn muestra la experiencia documentada del SVLE del COI a lo largo demĂĄs de una dĂ©cada de uso de este instrumento, demostrando que el SVLE representa una herramienta Ăștil, sencilla y ĂĄgil parael monitoreo de incidencias sanitarias