Innovative Approaches To Nursing Administration Education; A Systematic Review Based Study

Background: Nursing administration education plays a crucial role in the development of skilled leaders in the ever-evolving healthcare industry. To meet the current challenges in healthcare, it is crucial to employ innovative pedagogical approaches. These approaches include the integration of virtual reality simulations, fostering interdisciplinary collaboration, utilizing real-world case studies, implementing telehealth platforms, and establishing mentorship programs. Addressing this need for forward-thinking nursing administrators is imperative. Aim: This study comprehensively examines the impact of these innovative strategies on nursing administration education. It assesses how their integration enhances decision-making, communication, strategic thinking, technological proficiency, and leadership skills among students. The goal is to illuminate the potential of these approaches in molding skilled healthcare leaders. Method: A mixed-methods approach is utilized. Qualitative interviews with nursing administration students exposed to innovative approaches provide insights. Thematic analysis is employed to extract meaningful patterns, capturing both subjective experiences and skill development outcomes. Results: Findings highlight the transformative potential of innovative approaches in nursing administration education. Virtual reality simulations enhance decision-making, interdisciplinary collaboration fosters effective communication and teamwork, real-world case studies cultivate strategic thinking, telehealth platforms enhance remote service proficiency, and mentorship programs empower leadership competencies. Conclusion: This study underscores the pivotal role of innovation in shaping adept nursing administrators. Integration of innovative approaches equips healthcare leaders with holistic perspectives, adaptable skills, and technological readiness. As healthcare systems evolve, these approaches offer promise for addressing challenges effectively. Innovative Contribution: By delving into cutting-edge nursing administration education, this study offers insights that reshape healthcare leadership. It bridges theory and practice, equipping future administrators to navigate the dynamic healthcare landscape

A Comprehensive Survey on Machine Learning Methods for Handover Optimization in 5G Networks

One of the key features of mobile networks in this age of mobile communication is seamless communication. Handover (HO) is a critical component of next-generation (NG) cellular communication networks, which requires careful management since it poses several risks to qualityof-service (QoS), including a decrease in average throughput and service disruptions. Due to the dramatic rise in base stations (BSs) and connections per unit area brought about by new fifthgeneration (5G) network enablers, such as Internet of things (IoT), network densification, and mmwave communications, HO management has become more challenging. The degree of difficulty is increased in light of the strict criteria that were recently published in the specifications of 5G networks. In order to address these issues more successfully and efficiently, this study has explored and examined intelligent HO optimization strategies using machine learning models. Furthermore, the significant goal of this review is to present the state of cellular networks as they are now, as well as to talk about mobility and home office administration in 5G alongside the overall features of 5G networks. This work presents an overview of machine learning methods in handover optimization and of the various data availability for evaluations. In the final section, the challenges and future research directions are also detailed

Effectiveness of a Separate Training Center for Peritoneal Dialysis Patients

The aim of this study is to analyze the patients′ database of the Baxter′s Training Peritoneal Dialysis Program (BTPDP) adopted at the Baxter Renal Education Center (BREC), Riyadh, Saudi Arabia in order to determine its effectiveness in the management, compliance, and outcome of the trained peritoneal dialysis (PD) patients. The study analyzes the database of the BTPDP, which includes the demographic data, duration of follow-up, complications, and outcome of the patients trained on PD between September 2003 and November 2007. Records of 376 patients with a mean age of 46.0 ± 22.6 years were available in the database for analysis. Of them, 187 (49.7%) were males, 312 (82.9%) were trained at the BREC, 315 (83.8%) were new PD patients, and 298 (79.3%) were trained on automated PD (APD). The dropouts during the study period included 172 patients (46%); 42 (24.4%) were transplanted, 45 (26.2%) switched to hemodialysis, 57 (33.1%) died and 28 (16.3%) were lost to follow-up. A comparison was made between the group trained at the BREC and the group trained at the hospital. There was an overwhelming adoption of BTPDP by the different hospitals during the study period (p < 0.00001). There were 264 (84.6%) patients trained on APD at the BREC vs. 34 (53.1%) at the hospital (p < 0.00001), and the patients trained at the BREC had significantly less dropouts than those trained at the hospital during the study period 135 (43.3%) vs. 38 (59.4%) respectively (p < 0.02). The mean period of follow-up was significantly different between the patients trained at the BREC and those trained at the referring hospital (390 ± 461 days vs. 679 ± 779 days respectively (p < 00000.8). Also, there was a trend for better technique survival after the second year, among the patients trained at the BREC. We conclude that the BREC model has increased the recruitment to PD, and helped in spreading this method of renal replacement therapy among patients. This model emphasizes the role of a designated training course by an expert team, and unifies the training standards. Furthermore, application of this model can be expanded nationwide and even to other countries

Sustainability assessment of symbiotic processes for the reuse of phosphogypsum

The conversion of by-products to resources is a novel approach for enhancing circular economy through increasing the lifecycle of resources, however, it does not always achieve sustainability outcomes. A life cycle assessment has been conducted to assess the economic and environmental implications of the conversion of phosphogypsum, which is a by-product from phosphoric acid manufacture, to useful resources such as paper and fertilizer. The current research found that the phosphogypsum based paper and fertilizer are neither environmentally nor economically better than conventional products due to the raw materials used that leads to higher environmental impact and economic cost. However, phosphogypsum based products offers some social benefits such as additional employment creation and enhanced intergenerational equity. Further investigation into chemical process design in terms of reagent selection for precipitation reactions is needed to achieve the economic and environmental feasibility of the products based on these by-products

Cytotoxic Potential of Alternaria tenuissima AUMC14342 Mycoendophyte Extract: A Study Combined with LC-MS/MS Metabolic Profiling and Molecular Docking Simulation

Breast, cervical, and ovarian cancers are among the most serious cancers and the main causes of mortality in females worldwide, necessitating urgent efforts to find newer sources of safe anticancer drugs. The present study aimed to evaluate the anticancer potency of mycoendophytic Alternaria tenuissima AUMC14342 ethyl acetate extract on HeLa (cervical cancer), SKOV-3 (ovarian cancer), and MCF-7 (breast adenocarcinoma) cell lines. The extract showed potent effect on MCF-7 cells with an IC50 value of 55.53 μg/mL. Cell cycle distribution analysis of treated MCF-7 cells revealed a cell cycle arrest at the S phase with a significant increase in the cell population (25.53%). When compared to control cells, no significant signs of necrotic or apoptotic cell death were observed. LC-MS/MS analysis of Alternaria tenuissima extract afforded the identification of 20 secondary metabolites, including 7-dehydrobrefeldin A, which exhibited the highest interaction score (−8.0156 kcal/mol) in molecular docking analysis against human aromatase. Regarding ADME pharmacokinetics and drug-likeness properties, 7-dehydrobrefeldin A, 4’-epialtenuene, and atransfusarin had good GIT absorption and water solubility without any violation of drug-likeness rules. These findings support the anticancer activity of bioactive metabolites derived from endophytic fungi and provide drug scaffolds and substitute sources for the future development of safe chemotherapy

Evaluating the role of next-generation sequencing and radiological techniques in rare disease diagnosis: Challenges and opportunities

Aim: This article evaluates the utility of next-generation sequencing (NGS) and radiological techniques in the diagnosis of rare diseases, emphasizing the challenges and opportunities presented by these technologies. Methods: A comprehensive review of existing literature on NGS technologies, including first, second, and third-generation sequencing methods, as well as their applications in genomics, transcriptomics, and epigenomics, was conducted alongside radiological imaging techniques such as MRI and CT scans. Results: NGS has revolutionized rare disease diagnosis by enabling high-throughput, cost-effective sequencing, facilitating the identification of pathogenic mutations, and advancing personalized medicine. Radiological techniques provide complementary insights into anatomical abnormalities and disease progression. Despite significant advantages, challenges such as data interpretation, cost, and ethical considerations persist. Conclusion: NGS and radiological imaging offer transformative potential in rare disease diagnosis, enhancing our understanding of genetic and anatomical aspects of disorders and enabling targeted therapeutic approaches. Continued technological advancements and integrative analyses with other omics data and imaging findings will further enhance their diagnostic utility

Global economic burden of unmet surgical need for appendicitis

Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US $92 492 million using approach 1 and$73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was $95 004 million using approach 1 and$75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially

Global economic burden of unmet surgical need for appendicitis

Background There is a substantial gap in provision of adequate surgical care in many low- and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US $92 492 million using approach 1 and$73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was $95 004 million using approach 1 and$75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially