Multiwavelength analysis of brightness variations of 3C~279: Probing the relativistic jet structure and its evolution

We studied the correlation between brightness and polarization variations in 3C~279 at different wavelengths, over time intervals long enough to cover the time lags due to opacity effects. We used these correlations together with VLBI images to constrain the radio and high energy source position.We made 7 mm radio continuum and $R$-band polarimetric observations of 3C~279 between 2009 and 2014. The radio observations were performed at the Itapetinga Radio Observatory, while the polarimetric data were obtained at Pico dos Dias Observatory, both in Brazil. We compared our observations with the $\gamma$-ray Fermi/LAT and $R$-band SMARTS light curves. We found a good correlation between 7~mm and $R$-band light curves, with a delay of $170 \pm 30$ days in radio, but no correlation with the $\gamma$ rays. However, a group of several $\gamma$-ray flares in April 2011 could be associated with the start of the 7 mm strong activity observed at the end of 2011.We also detected an increase in $R$-band polarization degree and rotation of the polarization angle simultaneous with these flares. Contemporaneous VLBI images at the same radio frequency show two new strong components close to the core, ejected in directions very different from that of the jet.The good correlation between radio and $R$-band variability suggests that their origin is synchrotron radiation. The lack of correlation with $\gamma$-rays produced by the Inverse Compton process on some occasions could be due to the lack of low energy photons in the jet direction or to absorption of the high energy photons by the broad line region clouds. The variability of the polarization parameters during flares can be easily explained by the combination of the jet polarization parameters and those of newly formed jet components.Comment: 11 pages, 6 figures, 2 tables. Accepted by A&

A panchromatic spatially resolved study of the inner 500pc of NGC1052 -- II: Gas excitation and kinematics

We map the optical and near-infrared (NIR) emission-line flux distributions and kinematics of the inner 320$\times$535pc$^2$ of the elliptical galaxy NGC1052. The integral field spectra were obtained with the Gemini Telescope using the GMOS-IFU and NIFS instruments, with angular resolutions of 0''88 and 0''1 in the optical and NIR, respectively. We detect five kinematic components: (1 and 2) Two spatially unresolved components, being a broad line region visible in H$\alpha$, with a FWHM of $\sim$3200km s$^{-1}$ and an intermediate-broad component seen in the [OIII]$\lambda \lambda$4959,5007 doublet; (3) an extended intermediate-width component with 280<FWHM<450km s$^{-1}$ and centroid velocities up to 400km s$^{-1}$, which dominates the flux in our data, attributed either to a bipolar outflow related to the jets, rotation in an eccentric disc or a combination of a disc and large-scale gas bubbles; (4 and 5) two narrow (FWHM<150km s$^{-1}$) components, one visible in [OIII], and one visible in the other emission lines, extending beyond the field-of-view of our data, which is attributed to large-scale shocks. Our results suggest that the ionization within the observed field of view cannot be explained by a single mechanism, with photoionization being the dominant mechanism in the nucleus with a combination of shocks and photoionization responsible for the extended ionization.Comment: Accepted at MNRAS. 17 pages, 17 figure

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030