11 research outputs found
Solid aggregates: (a) ‘calcification’, (b) ‘free clot’ (c) and ‘filiform clot’.
<p>Solid aggregates: (a) ‘calcification’, (b) ‘free clot’ (c) and ‘filiform clot’.</p
Discrete multi-physics: A mesh-free model of blood flow in flexible biological valve including solid aggregate formation
<div><p>We propose a mesh-free and discrete (particle-based) multi-physics approach for modelling the hydrodynamics in flexible biological valves. In the first part of this study, the method is successfully validated against both traditional modelling techniques and experimental data. In the second part, it is further developed to account for the formation of solid aggregates in the flow and at the membrane surface. Simulations of various types of aggregates highlight the main benefits of discrete multi-physics and indicate the potential of this approach for coupling the hydrodynamics with phenomena such as clotting and calcification in biological valves.</p></div
Hard membrane: Comparison between simulations and experiments from [24].
<p>Hard membrane: Comparison between simulations and experiments from [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0174795#pone.0174795.ref024" target="_blank">24</a>].</p
Geometric parameters, fluid conditions, and membrane constants used in the simulations and in the experiments.
<p>Geometric parameters, fluid conditions, and membrane constants used in the simulations and in the experiments.</p
Valve geometry and types of particles used in the simulations.
<p>Valve geometry and types of particles used in the simulations.</p
106學年度-資訊工程學系學士班轉學考2年級-國文
<p>Velocity magnitude (a), velocity vectors (b) and shear stress (c) at 0.2 m s<sup>-1</sup> (left) and 0.9 m s<sup>-1</sup> (right) calculated with CFD.</p
Velocity vectors illustrating how the presence of the aggregate affects the hydrodynamics: (a) ‘calcification’, (b) ‘free clot’.
<p>Velocity vectors illustrating how the presence of the aggregate affects the hydrodynamics: (a) ‘calcification’, (b) ‘free clot’.</p
Algorithm for circular and filiform aggregates.
<p>Algorithm for circular and filiform aggregates.</p
Comparison between simulations and experiments from [24]: (a) intermediate membrane, (b) soft membrane.
<p>Comparison between simulations and experiments from [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0174795#pone.0174795.ref024" target="_blank">24</a>]: (a) intermediate membrane, (b) soft membrane.</p