479 research outputs found

    Manipulated Manipulation: The Political Origins and Implications of Shakespeare\u27s Henry V

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    Shakespeare’s Henry V has long been one of the most ambiguous adaptations of the story of England’s most celebrated historical figure: King Henry V. This adaptation raises the question of why Shakespeare presents Henry V in a way that not only differs significantly from the other accounts of Henry V’s life, but is also entirely ambiguous as to whether this presentation of Henry V’s character is optimistic or pessimistic in nature. In my thesis, I will argue that the ambiguities present in Henry V are actually a result of Shakespeare\u27s own stress over the political succession looming over England at the time of the play’s creation, and how those fears, questions, and concerns over leadership seep into his work

    Uncomplicating the business of repositories

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    In this presentation, we discuss how our library runs our repository in production to meet the needs of our “business” as efficiently as possible. We have an interest in limiting the number of digital platforms we manage, for the purposes of sustainability and efficiency, but we must also consider how well a general platform can meet specific user needs. A governance group of administrators, in conference with stakeholders and developers, seeks to find the best way to accommodate each collection or functional need, with an eye to minimizing technical complexity, offering stakeholders self-serve options when possible, and maintaining a single canonical copy of each object. We will present some case studies of how material has been handled in our developing digital ecosystem, where preservation and access sometimes present conflicting priorities. We are exploring how our repository can best evolve to support our aims of making data and documents freely available

    Defensive Design: Developing a System-Agnostic Repository for Sustainable Long-Term Preservation

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    Colenda, the University of Pennsylvania Libraries’ digital repository, was designed to promote longterm preservation. Its infrastructure is comprised of components selected to concentrate on factors that are of the most importance and that pose the greatest risks for long-term preservation of digital assets: safe file storage, the ability to track changes to objects over time, mechanisms for object management and discoverability, and migration paths that guarantee that objects can be safely migrated to new software and new versions of existing systems while preventing data loss. Favoring a pluggable architecture and preservation of software-agnostic representations of objects in order to keep future repository development plans flexible and open, our approach minimizes the risk of data loss in the long term and has allowed us to design a system in which the right tools for the task are always an option. In this paper, we will enumerate the risks/concerns influencing our design decisions and show how our approach addresses them while retaining a connection to the central open-source projects of the community, Fedora and Samvera, that make up significant portions of our stack

    Introduction

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    This article explores the interplay between journalism and experience in narrative and literary forms of journalism

    Protective efficacy of a recombinant plague vaccine when co-administered with another sub-unit or live attenuated vaccine.

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    Vaccines against bioterrorism agents offer the prospect of providing high levels of protection against airborne pathogens. However, the diversity of the bioterrorism threat means that it may be necessary to use several vaccines simultaneously. In this study we have investigated whether there are changes to the protective immune response to a recombinant sub-unit plague vaccine when it is co-administered with other sub-unit or live attenuated vaccines. Our results indicate that the co-administration of these vaccines did not influence the protection afforded by the plague vaccine. However, the co-administration of the plague sub-unit vaccine with a live vaccine resulted in markedly increased levels of IgG2a subclass antibodies, and markedly reduced levels of IgG1 subclass antibodies, to the plague sub-unit vaccine. This finding might have implications when considering the co-administration of other vaccine combinations

    A3_1 ”Scared Potter?”: The Force of Spells

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    In this paper we investigate the magnitude of the force experienced by a body following an impact from a spell in the Harry Potter film series. After comparing five different spells we determined that the strongest spell was cast by the character Dobby, producing a force of 3600N. Comparing this to the force of a static push, we find that this force is not large enough to propel a human several meters in the real world

    A3_5 Fifty Shades of CO2

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    In this article we consider the environmental effects if the Fifty Shades of Grey series had not been published. We investigate the number of trees required to produce all the books sold and relate this to the amount of carbon that could have been stored had these trees remained in place since date of publishing. Using this we found the amount of CO2 that could have been stored in these trees to be 179,200 tonnes. This is a negligible amount when compared to road transport and power station emissions for just one day

    Assessment of Feeding Behavior in Laboratory Mice

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    The global obesity epidemic has heightened the need for an improved understanding of how body weight is controlled, and research using mouse models is critical to this effort. In this perspective, we provide a conceptual framework for investigation of feeding behavior in this species, with an emphasis on factors that influence study design, data interpretation, and relevance to feeding behavior in humans. Although we focus on the mouse, the principles presented can be applied to most other animal models. This document represents the current consensus view of investigators from the National Institutes of Health (NIH)-funded Mouse Metabolic Phenotyping Centers (MMPCs)

    Assessment of health in human faces is context-dependent

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    This work was supported by the National Environment Research Council, UK (KM), Unilever Research & Development USA and the Economic and Social Research Council (RW, DP).When making decisions between options, humans are expected to choose the option that returns the highest benefit. In practice, however, adding inferior alternatives to the choice set can alter these decisions. Here we investigated whether decisions over the facial features that people find healthy looking can also be affected by the context in which they see those faces. To do this we examined the effect of choice set on the perception of health of images of faces of light-skinned Caucasian females. We manipulated apparent facial health by changing yellowness of the skin: the healthy faces were moderately yellow and the less healthy faces were either much more yellow or much less yellow. In each experiment, two healthy faces were presented along with a third, less healthy face. When the third face was much more yellow, participants chose the more yellow of the two healthy faces more often as the most healthy. However, when the third face was the least yellow, participants chose the less yellow of the two healthy faces more often. A further experiment confirmed that this result is not due to a generalised preference for an intermediate option. These results extend our understanding of context-dependent decision-making in humans, and suggest that comparative evaluation may be a common feature across many different kinds of choices that humans have to make.PostprintPeer reviewe
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