IoT end-user applications provisioning in the cloud: State of the art

© 2016 IEEE. Internet of Things (IoT) is expected to enable a myriad of end-user applications by interconnecting physical objects. Cloud computing is a promising paradigm for provisioning IoT end-user applications in a cost-efficient manner. IoT end-user applications are provisioned in cloud settings using PaaS and offered as SaaS. This paper focuses on the PaaS aspects of IoT end-user applications provisioning. It critically reviews the state of the art. The critical review discusses the PaaS on the whole spectrum of IoT verticals and also the PaaS dealing with specific IoT verticals

A comprehensive survey on Fog Computing: State-of-the-art and research challenges

Cloud computing with its three key facets (i.e., Infrastructure-as-a-Service, Platform-as-a-Service, and Softwareas- a-Service) and its inherent advantages (e.g., elasticity and scalability) still faces several challenges. The distance between the cloud and the end devices might be an issue for latencysensitive applications such as disaster management and content delivery applications. Service level agreements (SLAs) may also impose processing at locations where the cloud provider does not have data centers. Fog computing is a novel paradigm to address such issues. It enables provisioning resources and services outside the cloud, at the edge of the network, closer to end devices, or eventually, at locations stipulated by SLAs. Fog computing is not a substitute for cloud computing but a powerful complement. It enables processing at the edge while still offering the possibility to interact with the cloud. This paper presents a comprehensive survey on fog computing. It critically reviews the state of the art in the light of a concise set of evaluation criteria. We cover both the architectures and the algorithms that make fog systems. Challenges and research directions are also introduced. In addition, the lessons learned are reviewed and the prospects are discussed in terms of the key role fog is likely to play in emerging technologies such as tactile Internet

Lactation and neonatal nutrition: defining and refining the critical questions.

This paper resulted from a conference entitled "Lactation and Milk: Defining and refining the critical questions" held at the University of Colorado School of Medicine from January 18-20, 2012. The mission of the conference was to identify unresolved questions and set future goals for research into human milk composition, mammary development and lactation. We first outline the unanswered questions regarding the composition of human milk (Section I) and the mechanisms by which milk components affect neonatal development, growth and health and recommend models for future research. Emerging questions about how milk components affect cognitive development and behavioral phenotype of the offspring are presented in Section II. In Section III we outline the important unanswered questions about regulation of mammary gland development, the heritability of defects, the effects of maternal nutrition, disease, metabolic status, and therapeutic drugs upon the subsequent lactation. Questions surrounding breastfeeding practice are also highlighted. In Section IV we describe the specific nutritional challenges faced by three different populations, namely preterm infants, infants born to obese mothers who may or may not have gestational diabetes, and infants born to undernourished mothers. The recognition that multidisciplinary training is critical to advancing the field led us to formulate specific training recommendations in Section V. Our recommendations for research emphasis are summarized in Section VI. In sum, we present a roadmap for multidisciplinary research into all aspects of human lactation, milk and its role in infant nutrition for the next decade and beyond

Blockchain and the Tokenization of the Individual: Societal Implications

We are living in a world where the very systems upon which trust is based are being challenged by new and exciting paradigm shifts. Centralization whether in the form of governments, financial institutions, enterprises and organizations is simply being challenged because of the lack of trust associated with data governance often experienced in the form of data breaches or simply a monetization of our data without our permission and/or incentives to participate in this emerging decentralization of structures. We see this trust deficit challenging the very institutions we have depended on including but not limited to financial institutions, private enterprises or government bodies. A new “social contract” is required as we continuously evolve into more decentralized and self-governing (or semi self-governing) entities. We will see more development in digital sovereignty with the caveat that a governance model will need to be defined. This position paper will present evidence that supports the premise that blockchain and individual tokenization could provide a new social contract

Lactation and neonatal nutrition: defining and refining the critical questions.

This paper resulted from a conference entitled "Lactation and Milk: Defining and refining the critical questions" held at the University of Colorado School of Medicine from January 18-20, 2012. The mission of the conference was to identify unresolved questions and set future goals for research into human milk composition, mammary development and lactation. We first outline the unanswered questions regarding the composition of human milk (Section I) and the mechanisms by which milk components affect neonatal development, growth and health and recommend models for future research. Emerging questions about how milk components affect cognitive development and behavioral phenotype of the offspring are presented in Section II. In Section III we outline the important unanswered questions about regulation of mammary gland development, the heritability of defects, the effects of maternal nutrition, disease, metabolic status, and therapeutic drugs upon the subsequent lactation. Questions surrounding breastfeeding practice are also highlighted. In Section IV we describe the specific nutritional challenges faced by three different populations, namely preterm infants, infants born to obese mothers who may or may not have gestational diabetes, and infants born to undernourished mothers. The recognition that multidisciplinary training is critical to advancing the field led us to formulate specific training recommendations in Section V. Our recommendations for research emphasis are summarized in Section VI. In sum, we present a roadmap for multidisciplinary research into all aspects of human lactation, milk and its role in infant nutrition for the next decade and beyond

A Core Outcome Measurement Set for Pediatric Critical Care

Objectives: To identify a PICU Core Outcome Measurement Set (PICU COMS), a set of measures that can be used to evaluate the PICU Core Outcome Set (PICU COS) domains in PICU patients and their families. Design: A modified Delphi consensus process. Setting: Four webinars attended by PICU physicians and nurses, pediatric surgeons, rehabilitation physicians, and scientists with expertise in PICU clinical care or research (n = 35). Attendees were from eight countries and convened from the Pediatric Acute Lung Injury and Sepsis Investigators Pediatric Outcomes STudies after PICU Investigators and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network PICU COS Investigators. Subjects: Measures to assess outcome domains of the PICU COS are as follows: cognitive, emotional, overall (including health-related quality of life), physical, and family health. Measures evaluating social health were also considered. Interventions: None. Measurements and Main Results: Measures were classified as general or additional based on generalizability across PICU populations, feasibility, and relevance to specific COS domains. Measures with high consensus, defined as 80% agreement for inclusion, were selected for the PICU COMS. Among 140 candidate measures, 24 were delineated as general (broadly applicable) and, of these, 10 achieved consensus for inclusion in the COMS (7 patient-oriented and 3 family-oriented). Six of the seven patient measures were applicable to the broadest range of patients, diagnoses, and developmental abilities. All were validated in pediatric populations and have normative pediatric data. Twenty additional measures focusing on specific populations or in-depth evaluation of a COS subdomain also met consensus for inclusion as COMS additional measures. Conclusions: The PICU COMS delineates measures to evaluate domains in the PICU COS and facilitates comparability across future research studies to characterize PICU survivorship and enable interventional studies to target long-term outcomes after critical illness.</p