Reinforced concrete two-span continuous deep beams

Ye

The Histone 3'-Terminal Stem-Loop-Binding Protein Enhances Translation through a Functional and Physical Interaction with Eukaryotic Initiation Factor 4G (eIF4G) and eIF3

Metazoan cell cycle-regulated histone mRNAs are unique cellular mRNAs in that they terminate in a highly conserved stem-loop structure instead of a poly(A) tail. Not only is the stem-loop structure necessary for 3'-end formation but it regulates the stability and translational efficiency of histone mRNAs. The histone stem-loop structure is recognized by the stem-loop-binding protein (SLBP), which is required for the regulation of mRNA processing and turnover. In this study, we show that SLBP is required for the translation of mRNAs containing the histone stem-loop structure. Moreover, we show that the translation of mRNAs ending in the histone stem-loop is stimulated in Saccharomyces cerevisiae cells expressing mammalian SLBP. The translational function of SLBP genetically required eukaryotic initiation factor 4E (eIF4E), eIF4G, and eIF3, and expressed SLBP coisolated with S. cerevisiae initiation factor complexes that bound the 5' cap in a manner dependent on eIF4G and eIF3. Furthermore, eIF4G coimmunoprecipitated with endogenous SLBP in mammalian cell extracts and recombinant SLBP and eIF4G coisolated. These data indicate that SLBP stimulates the translation of histone mRNAs through a functional interaction with both the mRNA stem-loop and the 5' cap that is mediated by eIF4G and eIF3

Alternative Cropping Systems for Traditional Monoculture Wheat Acres in the Southern Plains for Two Farm Sizes

The economics of five alternative crop production systems for the Southern Plains winter wheat production region, for both conventional tillage and no-till, for two farm sizes, was determined. Yield data were obtained from a three-year experiment conducted on three farm fields in the region. Tillage costs differ across farm size.Crop Production/Industries, Farm Management,

Bilharziasis in the African Infant and Child in the Mtoko District, Southern Rhodesia

A CAJM study on Bilharziasis in the African Infant in Southern Rhodesia during the 1950's.This study was undertaken with several objects in view.. First of all we wanted to know how frequently bilharziasis is likely to infest infants up to the age of two years in an endemic area. On first thoughts it would seem reasonable for the disease to be rarely encountered at this stage of life, since the African babe is seldom exposed directly to the streams or the water’s edge for fear that it might be drowned or injured by crocodiles. On the other hand, it must be admitted that the infant is often washed in water carried from the river in buckets or gourds, and unless the water is kept standing for 24 hours or boiled soon after collection, many of these children can be expected to acquire the disease. Then there is the possibility that the African infant born of a mother, herself probably infected for many years, may have a passive immunity conferred on it by her and is therefore more able to resist infection by the cercariae at this age than when it is older

The Most Explosive Race Problem is in the North

https://egrove.olemiss.edu/citizens_clip/1111/thumbnail.jp

The Mtoko quintuplets

A journal article on multiple pregnancies in the then Southern Rhodesia colony.The ratio of twin pregnancies to single pregnancies in England and the United. States of America is reported to be approximately one in eighty. By Hellins Law the incidence of quintuplets is therefore approximately one in 40 million. Quintuplets in these countries are obviously of extreme rarity. It is known, however, that in Rhodesia the incidence of twins is much higher among the African population and one would, therefore, expect the incidence of quintuplets to be higher. The incidence of twins is reported to be in the region of one in thirty-five, and by application of Hellins Law the incidence of quintuplets should be approximately one in 1.5 million births

Interpreting Injunctions

Injunctions are powerful remedies. They can force a person to act or refrain from acting, dictate policies that the government must adopt, or even refashion public institutions. Violations of an injunction can result in contempt. Despite the importance of injunctions, courts have applied an astonishingly wide range of contradictory approaches to interpreting them. They have likewise disagreed over whether appellate courts should defer to trial courts’ interpretations or instead review those interpretations de novo. Virtually no scholarship has been written on these topics. This Article proposes that courts apply a modified textualist approach to injunctions. Under this scheme, courts would generally interpret injunctions according to the ordinary meaning of their language. When a provision in an injunction quotes or incorporates by reference an extrinsic legal authority, such as a statute or contract, however, courts would interpret that provision according to the methodology they would ordinarily apply to that extrinsic authority. This proposed approach ensures that injunctions provide regulated parties with adequate notice of the conduct proscribed, curtails judicial abuses of power, and aligns tightly with the procedural rules that govern injunctions in both federal and state courts. This Article further proposes that appellate courts review trial courts’ interpretations of injunctions de novo. Independent appellate review naturally aligns with the textualist goal of implementing the best reading of an injunction, promotes principles of notice, and prevents government overreach