頭部の特徴的なメラノフォア斑点パターンに基づく近交系メダカの個体識別

京都大学新制・課程博士博士(人間健康科学)甲第24809号人健博第115号新制||人健||8(附属図書館)京都大学大学院医学研究科人間健康科学系専攻(主査)教授 中尾 恵, 教授 岡 昌吾, 教授 浅野 雅秀学位規則第4条第1項該当Doctor of Human Health SciencesKyoto UniversityDFA

On the pilot's behavior of detecting a system parameter change

The reaction of a human pilot, engaged in compensatory control, to a sudden change in the controlled element's characteristics is described. Taking the case where the change manifests itself as a variance change of the monitored signal, it is shown that the detection time, defined to be the time elapsed until the pilot detects the change, is related to the monitored signal and its derivative. Then, the detection behavior is modeled by an optimal controller, an optimal estimator, and a variance-ratio test mechanism that is performed for the monitored signal and its derivative. Results of a digital simulation show that the pilot's detection behavior can be well represented by the model proposed here

Reductions for monotone Boolean circuits

AbstractThe large class, say NLOG, of Boolean functions, including 0-1 Sort and 0-1 Merge, have an upper bound of O(nlogn) for their monotone circuit size, i.e., they have circuits with O(nlogn) AND/OR gates of fan-in two. Suppose that we can use, besides such normal AND/OR gates, any number of more powerful “F-gates” which realize a monotone Boolean function F with r(≥2) inputs and r′(≥1) outputs. Note that the cost of each AND/OR gate is one and we assume that the cost of each F-gate is r. Now we define: A Boolean function f in NLOG is said to be F-Easy if f can be constructed by a circuit with AND/OR/F gates whose total cost is o(nlogn). In this paper we show that 0-1 Merge is not F-Easy for an arbitrary monotone function F such that r′≤r/logr

Varying clinical presentations of NTM disease

The incidence rate of pulmonary nontuberculous mycobacterial disease (PNTMD) in Japan is the highest among major industrialized nations. Although the typical clinical course and radiological manifestations of PNTMD are different from those of pulmonary tuberculosis (TB), confusion about these mycobacterial diseases leads to a diagnostic pitfall. Diagnostic challenges include the coexistence of Mycobacterium tuberculosis (MTB) and nontuberculous mycobacteria (NTM), false positives for NTM in MTB nucleic acid amplification tests, microbial substitution, and abnormal radiological manifestations caused by NTM. Features of extrapulmonary NTM diseases, such as pleurisy, vertebral osteomyelitis, and disseminated disease, are different from the corresponding tuberculous diseases. Moreover, the immunological background of the patient (status of human immunodeficiency virus infection with or without antiviral therapy, continuation or discontinuation of immunosuppressive therapy, use of immune checkpoint inhibitor, pregnancy and delivery, etc.) influences the pathophysiology of mycobacterial diseases. This review describes the varying clinical presentations of NTM disease with emphasis on the differences from TB

Elderly patient with 5q spinal muscular atrophy type 4 markedly improved by Nusinersen

Available online 17 May 2020.ArticleJournal of the Neurological Sciences.415:116901(2020)journal articl

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