Sealing ceramic material in low melting point glass

A structured device placed in an aerated crucible to pack ceramics molding substance that is to be processed was designed. The structure is wrapped by sealing material made of pyrex glass and graphite foil or sheet with a weight attached on top of it. The crucible is made of carbon; the ceramics material to be treated through heat intervenient press process is molding substance consisting mainly of silicon nitride

Processing ceramics

A method of hot hydrostatic pressing of ceramics is described. A detailed description of the invention is given. The invention is explained through an example, and a figure illustrates the temperature and pressure during the hot hydrostatic pressing treatment

Low Serum Concentrations of Vitamin B6 and Iron Are Related to Panic Attack and Hyperventilation Attack

Patients undergoing a panic attack (PA) or a hyperventilation attack (HVA) are sometimes admitted to emergency departments (EDs). Reduced serotonin level is known as one of the causes of PA and HVA. Serotonin is synthesized from tryptophan. For the synthesis of serotonin, vitamin B6 (Vit B6) and iron play important roles as cofactors. To clarify the pathophysiology of PA and HVA, we investigated the serum levels of vitamins B2, B6, and B12 and iron in patients with PA or HVA attending an ED. We measured each parameter in 21 PA or HVA patients and compared the values with those from 20 volunteers. We found that both Vit B6 and iron levels were significantly lower in the PA/HVA group than in the volunteer group. There was no significant difference in the serum levels of vitamins B2 or B12. These results suggest that low serum concentrations of Vit B6 and iron are involved in PA and HVA. Further studies are needed to clarify the mechanisms involved in such differences

Association between Intra-Circuit Activated Clotting Time and Incidence of Bleeding Complications during Continuous Renal Replacement Therapy using Nafamostat Mesilate : a Retrospective Pilot Observational Study

It has been proposed that anticoagulant activity during continuous renal replacement therapy with nafamostat mesilate can be monitored by using intra-circuit activated clotting time. However, it is still unclear whether activated clotting time would be useful for this purpose. We conducted a retrospective study and included 76 patients who required continuous renal replacement therapy using nafamostat mesilate. We obtained information for pre- and post-filter activated clotting times and bleeding complications. We calculated time-weighted average activated clotting time. We divided the patients into three activated clotting time groups (low, middle, high) according to the tertiles of pre- and post-filter activated clotting times. Regarding post-filter time-weighted average activated clotting time, the incidence of bleeding complications in the high activated clotting time group was significantly higher than those in the low and middle activated clotting time groups (p=0.04). The incidences of bleeding complications were not significantly different among the three groups according to pre-filter time-weighted average activated clotting time (p=0.35). In sensitive analysis, the duration on continuous renal replacement therapy without bleeding complications was significantly longer for filters with post-tw ACT<262 than for those with post-tw ACT≧262 (p=0.03). This result suggested that post-filter time-weighted average activated clotting time might be a good predictor of bleeding complications during continuous renal replacement therapy with nafamostat mesilate. Further study is required to refute or confirm our findings

High pressure intensification of cassava resistant starch (RS3) yields

Cassava starch, typically, has resistant starch type 3 (RS3) content of 2.4%. This paper shows that the RS3 yields can be substantially enhanced by debranching cassava starch using pullulanase followed by high pressure or cyclic high-pressure annealing. RS3 yield of 41.3% was obtained when annealing was carried out at 400 MPa/60°C for 15 min, whereas it took nearly 8 h to obtain the same yield under conventional atmospheric annealing at 60°C. The yield of RS3 could be further significantly increased by annealing under 400MPa/60°C pressure for 15 min followed by resting at atmospheric pressure for 3 h 45 min, and repeating this cycle for up to six times. Microstructural surface analysis of the product under a scanning electron microscope showed an increasingly rigid density of the crystalline structure formed, confirming higher RS3 content

Organizacija i izvođenje kolegija Praksa u nastavi japanskog jezika i kulture

Considering the global increase in the number of Japanese language learners, the need to establish educational institutions (primary, secondary, higher education, non-school education) for Japanese language learning also arose in Croatia and, subsequently, the necessity to foster a new generation of qualified teachers with sufficient theoretical and practical background in teaching Japanese as a foreign language. The purpose of this paper is to examine and describe the process of implementing the graduate course Practice Teaching of the Japanese Language and Culture, along with its challenges such as online classes due to the Covid-19 pandemic. The paper discusses the role of teachers as facilitators, the role of students as trainees and the role of learners, i.e. the participants of an intensive two-week Japanese language course, which is part of the abovementioned graduate course. Furthermore, the paper discusses the learner survey and the trainee self-evaluation report with respect to the improvement of their knowledge.Globalni trend sve većeg rasta broja učenika japanskog jezika ukazao je i na pojavu potrebe u Hrvatskoj za osnivanjem obrazovnih ustanova (osnovno, srednje i visoko obrazovanje; neformalno obrazovanje) za učenje japanskog jezika, a posljedično i obrazovanjem i stvaranjem nove generacije kvalificiranih mladih učitelja, s adekvatnom teorijskom i praktičnom pozadinom i znanjem japanske didaktike i pedagogije. Cilj ovog rada je analizirati i opisati organizaciju i izvođenje kolegija Praksa u nastavi japanskog jezika i kulture na prvoj godini diplomskog studija Japanologije, osvrćući se i na izazove i ograničenja koja su proizašla zbog situacije s pandemijom bolesti Covid-19 i online izvođenja nastave. Nadalje, rad će također raspraviti i ulogu nastavnika kao moderatora/facilitatora, studenata kao praktikanta i polaznika kao učenika na intenzivnom dvotjednom online tečaju za građane, koji je dio gore spomenutog diplomskog kolegija. Na kraju, rad će se, na temelju rezultata i odgovara dobivenih iz ankete provedene na polaznicima tečaja (učenici), zatim saznanja iz izvješća samoevaluacije studenata (praktikanata) o obavljenoj praksi te evaluacije nastavnika, osvrnuti na poboljšanje znanja i vještina praktikanata na praksi

ジュウショウ カンジャ ノ ケットウ カンリ

Acute hyperglycemia is common in critically ill patients. In acute illness,“stress”in response to tissue injury or infection can have profound effects on carbohydrate metabolism. This type of hyperglycemia occurs despite elevation in insulin levels（insulin resistance）. It is well-known that stress-induced hyperglycemia reflects severity of illness and is associated with mortality and morbidity in various patient groups. Until２００1, stress induced hyperglycemia was believed to be a beneficial physiological response which promoted cellular glucose uptake. A single center prospective randomized control trial has shown that ventilated post-operative ICU patients allocated to intensive insulin therapy（IIT）（target glucose : 80-110 mg/dl）, had a 43 percent risk reduction in ICU mortality when compared with patients receiving conventional glucose control（target glucose level : 180-210 mg/dL）. In the Surviving Sepsis Campaign guidelines３０）, maintenance of blood glucose levels less than 150 mg/dl using continuous infusion of insulin and glucose was recommended with a Grade D recommendation. Using this approach, frequent glucose measurements（after introducing lowering blood glucose（every 30-60 mins）and on a regular basis（every 4 hrs）once the blood glucose concentration has stabilized）was also recommended. Using current available evidence, target blood glucose range for critically ill patients would be around 150 mg/dL and insulin should be started when blood glucose become ＞180 mg/dL. To provide safe blood glucose management, physicians should create well-developed insulin protocol and understand the reliability of blood glucose measurements on each device

Pathological Features of New Animal Models for Primary Biliary Cirrhosis

Primary biliary cirrhosis (PBC) is an autoimmune liver disease characterized by immune mediated biliary damage and frequent appearance of autoantibodies against mitochondrial enzymes. There is almost no useful animal model that is globally recognized and routinely used, however, several unique animal models manifested the characteristic clinical and pathological features of human PBC within the last 5 years. Herein, we compare the pathological features of previously reported and newly introduced novel animal models of PBC. Knowledge and understanding of the strengths and the limitations of each animal model have led to the development of promising therapies and novel tools to characterize these clinical conditions. Moreover, suitability of the model for the intended purpose should be confirmed by further research and analysis