A Dual Read-Out Assay to Evaluate the Potency of Compounds Active against Mycobacterium tuberculosis

PMCID: PMC3617142This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Direct Experimental Observation of 3D Vortex States in Multilayer Fe/Gd using Scanning Electron Microscopy with Polarization Analysis (SEMPA)

The global market for power solely for data center usage is estimated to be $12.4 billion by 2027[1]. In 2021, data center electricity consumption was ∼400 TW h, representing almost 2% of the global energy demand[2]. Ongoing efforts in spintronics, which use spin currents instead of traditional charge currents at a fraction of the power[3], are paving the way for significant savings, both financially and environmentally. There has been considerable research into alternatives for memory[4–6] including a magnetic structure known as a skyrmion, a self-supporting magnetic texture characterized by a non-trivial topology. Recent advances in creating room-temperature stable skyrmions has reignited interest in these objects. Building on previous work in the McMorran group, this research set out to build a more complete understanding of the 3D structure of metastable magnetic skyrmions, specifically in Fe/Gd thin films. This was done using traditional trans- mission electron microscope (TEM) techniques along with a unique scanning elec- tron microscope with polarization analysis at the University, the SEMPA. Data col- lected using a TEM in Lorentz mode, providing information integrated through the bulk of the material, was combined with data from SEMPA, providing surface- sensitive information about the top of the material. Analysis of the data suggests atopologically complex winding nature for the magnetization of skyrmions in this material. Presented herein is a brief introduction of the magnetic structures found in Fe/Gd multilayer thin films; an analysis using new analytical tools built for this purpose of the data collected; and a user’s manual for SEMPA, including mainte- nance and troubleshooting guidance

QRC Door: gerenciamento e controle de acesso físico

Orientador: Luiz Antonio Pereira NevesTrabalho (Graduação) - Universidade Federal do Paraná, Setor de Educação Profissional e Tecnológica, Curso de Tecnologia em Análise e Desenvolvimento de Sistema

História da educação física no ensino secundário : um estudo comparativo entre o Gymnásio Paranaense, o Ginásio Nacional e Ginásio Mineiro entre 1840a 1930

Orientador: professor Ms. Sérgio Roberto Chaves JuniorMonografia (licenciatura) - Universidade Federal do Paraná. Setor de Ciências Biológicas. Curso de Educação Físic

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety

A series of 3-methylidene-1H-indol-2(3H)-ones substituted with a 5- or 6- pentafluorosulfanyl group has been synthesized by a Knoevenagel condensation reaction of SF5-substituted oxindoles with a range of aldehydes. The resulting products were characterized by x-ray crystallography studies and were tested for biological activity versus a panel of cell lines and protein kinases. Some exhibited single digit nM activity