17 research outputs found

    A simple biodiversity assessment scheme supporting nature-friendly farm management

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    Farmers are important actors for regional development and biodiversity protection. Agri-environment-climate measures (AECM) are therefore a central tool of the European Union to support its biodiversity conservation policy. AECM generally reward farmers for fulfilling predefined management actions or avoiding specific practices. In contrast, result oriented AECM are intended to reward farmers for the outcome of nature friendly management practices. This approach gives more flexibility in management and hence promotes farmers engagement and autonomy. Besides educational activities and agricultural advisory services farmers need user friendly tools to assess biodiversity in order to meet result oriented AECM. Thus, we present a biodiversity assessment scheme for farmland using a set of indicators, which covers different aspects of biodiversity (flower colour index, butterfly abundance, landscape structuring degree, patch diversity index, aggregated biodiversity index) and can be applied at different spatial scales. The assessment scheme is applied on 44 farms in five countries (France, Switzerland, Germany, Italy, and Austria). To evaluate its appropriateness the relationship between the indicators and land-use intensity and plant species richness is investigated. Grasslands with low land-use intensity are more colourful grasslands, have significantly more butterflies and a higher aggregated biodiversity index than moderately and intensively used grasslands. The influence of management intensity on the landscape structuring degree is not significant. All indicators correlate with plant species richness at all spatial scales. The proposed assessment scheme serves as a tool for the detection of differences in biodiversity resulting from land-use practices, and can assist the monitoring of ROMs

    Patient-reported outcomes in metastatic castration-resistant prostate cancer

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    Many novel therapies are available for use in patients with metastatic castration-resistant prostate cancer (mCRPC), some of which convey substantial progression-free survival and overall survival benefits. Delaying disease progression and providing palliation of symptoms are primary therapeutic aims of treating patients with mCRPC; therefore, ensuring that the benefit-to-harm ratios are acceptable to patients, through systematic measurement of patient-reported outcomes (PROs) using validated tools, is vital. In this Perspectives, we appraised the published reports from clinical trials testing treatments of mCRPC over the past 5 years and found that PROs were either not being measured routinely, or if used, were often not reported adequately, thus hampering evaluation of the true effects of many of these treatments on patients' quality of life. Improvements are needed because data collected directly from patients, not just physician-collected safety data and adverse events, are crucial to inform clinical decision-making on treatment options

    A simple biodiversity assessment scheme supporting nature-friendly farm management

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    International audienceFarmers are important actors for regional development and biodiversity protection. Agri-environment-climate measures (AECM) are therefore a central tool of the European Union to support its biodiversity conservation policy. AECM generally reward farmers for fulfilling predefined management actions or avoiding specific practices. In contrast, result oriented AECM are intended to reward farmers for the outcome of nature friendly management practices. This approach gives more flexibility in management and hence promotes farmers engagement and autonomy. Besides educational activities and agricultural advisory services farmers need user friendly tools to assess biodiversity in order to meet result oriented AECM. Thus, we present a biodiversity assessment scheme for farmland using a set of indicators, which covers different aspects of biodiversity (flower colour index, butterfly abundance, landscape structuring degree, patch diversity index, aggregated biodiversity index) and can be applied at different spatial scales. The assessment scheme is applied on 44 farms in five countries (France, Switzerland, Germany, Italy, and Austria). To evaluate its appropriateness the relationship between the indicators and land-use intensity and plant species richness is investigated. Grasslands with low land-use intensity are more colourful grasslands, have significantly more butterflies and a higher aggregated biodiversity index than moderately and intensively used grasslands. The influence of management intensity on the landscape structuring degree is not significant. All indicators correlate with plant species richness at all spatial scales. The proposed assessment scheme serves as a tool for the detection of differences in biodiversity resulting from land-use practices, and can assist the monitoring of ROMs
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