1,688 research outputs found

    Coupling Manure Injection with Cover Crops to Enhance Nutrient Cycling

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    Large-scale hog (Sus scroja) production is a major agricultural enterprise in the Midwest. Large numbers of confined hogs produce about 50 million tons per year of swine manure in Iowa alone. Rapid expansion of concentrated animal feeding operations (CAFOs) has resulted in increased concentrations of manure nutrients in surface waters which contribute about 15% of the total nitrate load in the Mississippi River Basin. Producers are being encouraged to develop manure management practices that fulfill crop production requirements, while minimizing the potential for environmental pollution. The most commonly used manure management practice in the Midwest involves fall application to land where corn (Zea mays L.) will be grown in the subsequent growing season. Fall planted annual cover crops can capture manure nutrients and immobilize them in plant biomass, subsequently reducing the potential for nutrient loss through run-off or leaching. Decomposition of cover crop residue the following spring may help synchronize manure N availability and corn N uptake, improving nutrient-use efficiency within the crop rotation

    Helping Undergraduates Discover The Value Of A Dollar Through Self-Monitoring

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    Many college undergraduates lack basic financial management knowledge and skills while bearing ever increasing debt burdens upon graduation. In order to encourage students to become aware of their spending patterns and weigh those patterns against personal values, a self-monitoring project was implemented as a class activity. The resulting effect on financial behavior was examined. Analysis of participants’ self-reflection papers revealed that awareness of spending behaviors increased universally among participants, and a significant proportion of students spontaneously modified spending behaviors to more closely conform to personal values. Participants consistently reported the importance of a spending management tool in modifying spending behavior

    Estimating Atrazine Leaching in the Midwest

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    Data from seven Management Systems Evaluation Areas (MSEM) were used to test the sensitivity of a leaching model, PRZM-2, to a variety of hydrologic settings common in the Midwest. Atrazine leaching was simulated because the use of atrazine was prevalent in the MSEA studies and it frequently occurs in the region\u27s groundwater. Results of long-term simulations using regional and generalized input parameters produced ranks of leaching potential similar to those based on measurements. Short-term simulations used site-specific soil and chemical coefficients

    Mutations in the E2 glycoprotein and the 3\u27 untranslated region enhance chikungunya virus virulence in mice

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    Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection. Although studies of humans and experimentally infected animals suggest that CHIKV infection persists in musculoskeletal tissues, the mechanisms for this remain poorly understood. To evaluate this further, we isolated CHIKV from the serum of persistently infected Rag1 -/- mice at day 28. When inoculated into naive wild-type (WT) mice, this persistently circulating CHIKV strain displayed a capacity for earlier dissemination and greater pathogenicity than the parental virus. Sequence analysis revealed a nonsynonymous mutation in the E2 glycoprotein (E2 K200R) and a deletion within the 3' untranslated region (3'-UTR). The introduction of these changes into the parental virus conferred enhanced virulence in mice, although primary tropism for musculoskeletal tissues was maintained. The E2 K200R mutation was largely responsible for enhanced viral dissemination and pathogenicity, although these effects were augmented by the 3'- UTR deletion. Finally, studies with Irf3/Irf7 -/- and Ifnar1 -/- mice suggest that the E2 K200R mutation enhances viral dissemination from the site of inoculation independently of interferon regulatory factor 3 (IRF3)-, IRF7-, and IFNAR1-mediated responses. As our findings reveal viral determinants of CHIKV dissemination and pathogenicity, their further study should help to elucidate host-virus interactions that determine acute and chronic CHIKV infection
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