The 2-D magnetohydrostatic configurations leading to flares or quiescent filament eruptions

To investigate the cause of flares and quiescent filament eruptions the quasi-static evolution of a magnetohydrostatic (MHS) model was studied. The results lead to a proposal that: the sudden disruption of an active-region filament field configuration and the accompanying flare result from the lack of a neighboring equilibrium state as magnetic shear is increased above the critical value; and a quiescent filament eruption is due to an ideal MHD kink instability of a highly twisted detached flux tube formed by the increase of plasma current flowing along the length of the filament. A numerical solution was developed for the 2-D MHS equation for the self-consistent equilibrium of a filament and overlying coronal magnetic field. Increase of the poloidal current causes increase of magnetic shear. As shear increases past a critical point, there is a discontinuous topological change in the equilibrium configuration. It was proposed that the lack of a neighboring equilibrium triggers a flare. Increase of the axial current results in a detached tube with enough helical twist to be unstable to ideal MHD kink modes. It was proposed that this is the condition for the eruption of a quiescent filament

On the universality of the global slope -- anisotropy inequality

Recently, some intriguing results have lead to speculations whether the central density slope -- velocity dispersion anisotropy inequality (An & Evans) actually holds at all radii for spherical dynamical systems. We extend these studies by providing a complete analysis of the global slope -- anisotropy inequality for all spherical systems in which the augmented density is a separable function of radius and potential. We prove that these systems indeed satisfy the global inequality if their central anisotropy is $\beta_0\leq 1/2$. Furthermore, we present several systems with $\beta_0 > 1/2$ for which the inequality does not hold, thus demonstrating that the global density slope -- anisotropy inequality is not a universal property. This analysis is a significant step towards an understanding of the relation for general spherical systems.Comment: 8 pages, 1 figure, accepted for publication in Ap

An attractor for dark matter structures

Cosmological simulations of dark matter structures have identified a set of universal profiles, and similar characteristics have been seen in non-cosmological simulations. It has therefore been speculated whether these profiles of collisionless systems relate to accretion and merger history, or if there is an attractor for the dark matter systems. Here we identify such a 1-dimensional attractor in the 3-dimensional space spanned by the 2 radial slopes of the density and velocity dispersion, and the velocity anisotropy. This attractor effectively removes one degree of freedom from the Jeans equation. It also allows us to speculate on a new fluid interpretation for the Jeans equation, with an effective polytropic index for the dark matter particles between 1/2 and 3/4. If this attractor solution holds for other collisionless structures, then it may hold the key to break the mass-anisotropy degeneracy, which presently prevents us from measuring the mass profiles in dwarf galaxies uniquely.Comment: 7 pages, 2 figures, comments welcom

A statistical-mechanical explanation of dark matter halo properties

Cosmological N-body simulations have revealed many empirical relationships of dark matter halos, yet the physical origin of these halo properties still remains unclear. On the other hand, the attempts to establish the statistical mechanics for self-gravitating systems have encountered many formal difficulties, and little progress has been made for about fifty years. The aim of this work is to strengthen the validity of the statistical-mechanical approach we have proposed previously to explain the dark matter halo properties. By introducing an effective pressure instead of the radial pressure to construct the specific entropy, we use the entropy principle and proceed in a similar way as previously to obtain an entropy stationary equation. An equation of state for equilibrated dark halos is derived from this entropy stationary equation, by which the dark halo density profiles with finite mass can be obtained. We also derive the anisotropy parameter and pseudo-phase-space density profile. All these predictions agree well with numerical simulations in the outer regions of dark halos. Our work provides further support to the idea that statistical mechanics for self-gravitating systems is a viable tool for investigation.Comment: 5 pages, 4 figures, Accepted by A&

A theorem on central velocity dispersions

It is shown that, if the tracer population is supported by a spherical dark halo with a core or a cusp diverging more slowly than that of a singular isothermal sphere, the logarithmic cusp slope 'g' of the tracers must be given exactly by g=2b where b is their velocity anisotropy parameter at the center unless the same tracers are dynamically cold at the center. If the halo cusp diverges faster than that of the singular isothermal sphere, the velocity dispersion of the tracers must diverge at the center too. In particular, if the logarithmic halo cusp slope is larger than two, the diverging velocity dispersion also traces the behavior of the potential. The implication of our theorem on projected quantities is also discussed. We argue that our theorem should be understood as a warning against interpreting results based on simplifying assumptions such as isotropy and spherical symmetry.Comment: submitted to Ap

Advanced process monitoring and feedback control to enhance cell culture process production and robustness

It is common practice in biotherapeutic manufacturing to define a fixed-volume feed strategy for nutrient feeds based on historical cell demand. However, once the feed volumes are defined, they are inflexible to batch-to-batch variations in cell growth and physiology and can lead to inconsistent productivity and product quality. In an effort to control critical quality attributes and to apply Process Analytical Technology (PAT), we demonstrated three different and novel approaches for implementing online monitoring and feedback control to improve the performance and/or robustness of cell culture processes. First, we describe the first reported fed-batch process utilizing online amino acid measurements (glutamate) to trigger automatic feedback control delivering complex nutrient feed. More importantly, the resulting feed strategy was translated into a manufacturing-friendly manual feed strategy without impact on product quality. Second, we increase the complexity of the control strategy by designing multiple feedback control loops for all feed solutions based on varied inputs (bio-capacitance for cell mass, Nova-Flex for glucose), resulting in a truly fully automatic cell culture process. We then demonstrate the utility of the feedback control system to rescue a batch without manual intervention by automatically adjusting the feed in response to an excursion that was intentionally introduced. Finally, we describe the implementation of a new online monitoring instrument in combination with a logic control module to simultaneously monitor and control glucose and lactate with high frequency, resulting in cell culture process improvement. Together, the three cases presented here illustrate an advanced process control toolbox which can be readily applied to various cell lines, media systems, and processes to significantly increase productivity and improve robustness in manufacturing, with the goal of ensuring process performance and product quality consistenc

Dynamical models with a general anisotropy profile

Both numerical simulations and observational evidence indicate that the outer regions of galaxies and dark matter haloes are typically mildly to significantly radially anisotropic. The inner regions can be significantly non-isotropic, depending on the dynamical formation and evolution processes. In an attempt to break the lack of simple dynamical models that can reproduce this behaviour, we explore a technique to construct dynamical models with an arbitrary density and an arbitrary anisotropy profile. We outline a general construction method and propose a more practical approach based on a parameterized anisotropy profile. This approach consists of fitting the density of the model with a set of dynamical components, each of which have the same anisotropy profile. Using this approach we avoid the delicate fine-tuning difficulties other fitting techniques typically encounter when constructing radially anisotropic models. We present a model anisotropy profile that generalizes the Osipkov-Merritt profile, and that can represent any smooth monotonic anisotropy profile. Based on this model anisotropy profile, we construct a very general seven-parameter set of dynamical components for which the most important dynamical properties can be calculated analytically. We use the results to look for simple one-component dynamical models that generate simple potential-density pairs while still supporting a flexible anisotropy profile. We present families of Plummer and Hernquist models in which the anisotropy at small and large radii can be chosen as free parameters. We also generalize these two families to a three-parameter family that self-consistently generates the set of Veltmann potential-density pairs. (Abridged...)Comment: 18 pages, accepted for publication in A&