Flow over surface discontinuities in a marine environment

This study concentrates on analysis of LongEZ aircraft data taken offshore of the Atlantic Coast of the United States. Due to the land structure of the region, it was possible to isolate the effect of narrow land on air as it flows offshore. The narrow land (Outer Banks) separates inland water from the sea. With greater land fetch, the internal boundary layer (IBL) over land grows deeper and the eddies presumably grow larger. Larger eddies typically decay more slowly than smaller eddies, and so the turbulence advected from land with a larger land fetch should survive longer over the sea and be greater in magnitude than that with smaller land fetch. The turbulence is studied using aircraft eddy correlation data as the flow is advected over the water. As expected, greater and longer-lasting turbulence is present downstream from greater land widths. Aircraft data taken over the Gulf Stream (GS) boundary are analyzed to study the effects of the sea surface temperature (SST) front on downstream boundary layer structure. Unstable and stable flows are studied in this region. The stable flow case is found to have an upside-down structure, with greater turbulence aloft causing stress convergence at the surface, which acts to accelerate the flow. The local thermally generated pressure gradient is important in the momentum budget across the GS front in both flow cases. A synthetic aperture radar (SAR) image is analyzed qualitatively in the region between the Atlantic Coast and the Gulf Stream front for intercomparison of data and to examine the influences of varying static stabilities and surface conditions upon the backscatter shown in satellite images. The growth rates of the internal boundary layer due to flow over a heterogeneous surface including flow from land over the water and flow between cooler water and warmer water are calculated. These results are compared to similar calculations of growth rates from previous experiments. It is found that the growth rate of an internal boundary layer is dependent on surface roughness, despite the inclusion of σ[subscript w] in the normalization of the growth rate

Examination of Anger Prevalence in NCAA Division I Student-Athletes

Purpose: Anger associated with sports participation may affect inability to acutely process anger, may decrease performance and increase the likelihood of risk-taking behavior in collegiate athletes. Therefore, the purpose was to examine the prevalence of anger in collegiate student-athletes across sex, academic status, and sport type. Methods: A cross sectional study over a three-year period examined 759 NCAA Division I student-athletes at one institution (age=20±1 years; males: n=259; females: n=500) completed an optional pre-participation behavioral health screening questionnaire, personal demographic information and the Anger Index Self-Test. Results: Overall, 37.2% (n=282/759; males=127/259, 49.0%; females=155/500, 31.0%) of participants were at high-risk for anger. We identified a significant difference between the anger and sex [Χ2(2, N=759) =28.1, P≤0.01]. We also identified a significant difference between the anger and sport type [Χ2(8, N=759)=32.1, P≤0.01] with 55.2% (n=419/759) at moderate risk for anger despite sport type; with the highest percentages presenting high-risk for anger within power sports (n= 64/116, 55.2%) and ball sports (n=98/240, 40.8%). No significant differences were identified for anger risk and academic status (P=0.66). Conclusions: Female collegiate student-athletes demonstrated a higher prevalence of anger than male collegiate student-athletes, yet more males were high-risk. Most student-athletes displayed moderate-risk for anger across different sports. Anger across academic status was not significantly different implying that anger management and coping skills may need to be taught during their student-athlete tenure to mitigate the identified risk. A collegiate student-athlete’s inability to process anger may affect sports performance and have negative consequences on their personal and social life. A primary prevention mechanism exists to explore proper coping mechanisms for anger during sport before the onset of mental health conditions that could exacerbate the experience for the individual

Impact of Face Masks on Audiovisual Word Recognition in Young Children with Hearing Loss During the Covid-19 Pandemic

Objective: To investigate effects of surgical and transparent face masks during the Covid-19 pandemic on audiovisual speech recognition of words for deaf and hard-of-hearing children. Design: Recorded Word Intelligibility by Picture Identification test (WIPI) was presented in quiet via a computer monitor to children in a quiet test room. The acoustic power spectra of each mask type were compared to the baseline no mask condition. Percent correct word recognition was recorded for four mask conditions (no mask, surgical mask, transparent apron mask and ClearMask) in counterbalanced order. Repeated measures ANOVA was used to test for significant differences in word recognition scores across mask types. Study Sample: Thirteen children (3 to 7 years) in a private auditory oral school wearing hearing aids, bone-anchored hearing aids or cochlear implants. Children were excluded if English was not their primary language or if they had a severe speech-language delay, uncorrected vision loss, or developmental disorder that would affect the results. No children had been exposed to or had contracted the Covid-19 virus. Results: Acoustic spectra showed a decrease in the 2000-8000 Hz region for the transparent apron mask. The surgical mask and ClearMask showed fewer acoustic effects. Children with hearing aids performed similarly to children with cochlear implants. Word recognition was significantly poorer for surgical masks and transparent apron masks. The ClearMask condition was not significantly worse than the no mask condition for words in quiet. Conclusions: Standard surgical and custom apron shield masks significantly hampered word recognition, even in quiet conditions. The commercially available ClearMask did not significantly affect scores in quiet for young deaf and hard-of-hearing children, but scores were highly variable

Three-dimensional carbon nanotube yarn based solid state solar cells with multiple sensitizers exhibit high energy conversion efficiency

Fiber-type dye sensitized solar cells that are non-metallic, flexible, and thread-like in structure have many potential military and functional textile applications. With the use of quantum dots (QD), exciton transfer facilitators (Phenyl-C61-butyric acid methyl ester-PCBM) and Poly(3-hexylthiophene-2,5-diyl-P3HT), and careful preparation of the TiO2 oxide layer deposited on the carbon fiber working electrode, an optimized efficiency of 7.6% was obtained. Carbon nanotube yarn (CNTY) was used to prepare both the working and counter electrodes of the fabricated cells. TiCl4 annealing of the TiO2 layer was carried out and the resulting oxide layer morphology was found to be very uniform. The quantum dots, cadmium sulfide (CdS) and cadmium selenide (CdSe), were deposited directly onto the surface of the nanoporous oxide layer using chemical bath deposition (CBD). Also, the P3HT and PCBM were applied and deposited via CBD on the working electrode as a bulk heterojunction material. Potentiometric characterization of the prepared cells performed at different cell lengths and showed that the maximum efficiency was obtained for cells approximately 3.5 cm in length. Photovoltaic performance of these solid state three dimensional cells was also carried out for different cell configurations

Oil disturbance reduces infaunal family richness but does not affect phylogenetic diversity

Infaunal organisms are susceptible to disturbances such as hypoxia and sediment contamination; changes in infaunal community structure are therefore often used as indicators of anthropogenic disturbance. Susceptibility to disturbance varies across taxa, either due to physiological factors or to behaviors or functional roles that increase exposure. Both sources of variability are likely to be heritable and shared among related taxa. Thus, we would expect oil disturbance to disproportionately affect related taxa and therefore decrease phylogenetic diversity (PD). We test this hypothesis for a shallow water marine infaunal community using a simulation approach that iteratively removes clades with shared vulnerability to oil exposure. Infauna were sampled at two sites in the Chandeleur Islands, LA, that reflect different exposures to crude oil after the Deepwater Horizon event. Seagrass and adjacent bare sediment habitats were sampled in 2015, 5 years after initial oil exposure, and again in 2016 after an acute re-oiling event. We found that strong correlation between PD and family richness masked any detectable PD patterns with oil exposure. For our full community tree, sensitivity analysis indicated that the removal of larger clades did not disproportionately reduce PD, against our prediction. For this pair of sites, PD did not provide a better metric for assessing the impacts of oil exposure than family richness alone. It is possible, however, that finer-scale taxonomic resolution of infaunal communities may better decouple PD from taxonomic richness. More work is needed to fully evaluate the impacts of disturbance on PD

Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo

The objective of this study was to test the efficacy of an inhibitor of the New Delhi metallo-β- lactamase (NDM-1). Inhibiting expression of this type of antibiotic-resistance gene has the potential to restore antibiotic susceptibility in all bacteria carrying the gene.Methods: We have constructed a peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) that selectively inhibits the expression of NDM-1 and examined its ability to restore susceptibility to meropenem in vitro and in vivo.Results:In vitro, the PPMO reduced the MIC of meropenem for three different genera of pathogens that express NDM-1. In a murine model of lethal E. coli sepsis, the PPMO improved survival (92%) and reduced systemic bacterial burden when given concomitantly with meropenem.Conclusions: These data show that a PPMO can restore antibiotic susceptibility in vitro and in vivo and that the combination of PPMO and meropenem may have therapeutic potential against certain class B carbapenem- resistant infections in multiple genera of Gram-negative pathogens

Determination of Optimal Deployment Strategy For Reboa in Patients With Non-Compressible Hemorrhage Below the Diaphragm

BACKGROUND: Non-compressible truncal hemorrhage (NCTH) is the leading cause of preventable death after trauma. Resuscitative endovascular balloon occlusion of the aorta (REBOA) achieves temporary hemorrhage control, supporting cardiac and cerebral perfusion prior to definitive hemostasis. Aortic zone selection algorithms vary among institutions. We evaluated the efficacy of an algorithm for REBOA use. METHODS: A multicenter prospective, observational study conducted at six level 1 trauma centers over 12 months. Inclusion criteria were age \u3e15 years with evidence of infradiaphragmatic NCTH needing emergent hemorrhage control within 60 min of ED arrival. An algorithm characterized by the results of focused assessment with sonography in trauma and pelvic X-ray was assessed post hoc for efficacy in a cohort of patients receiving REBOA. RESULTS: Of the 8166 patients screened, 78 patients had a REBOA placed. 21 patients were excluded, leaving 57 patients for analysis. The algorithm ensures REBOA deployment proximal to hemorrhage source to control bleeding in 98.2% of cases and accurately predicts the optimal REBOA zone in 78.9% of cases. If the algorithm was violated, bleeding was optimally controlled in only 43.8% (p=0.01). Three (75.0%) of the patients that received an inappropriate zone 1 REBOA died, two from multiple organ failure (MOF). All three patients that died with an inappropriate zone 3 REBOA died from exsanguination. DISCUSSION: This algorithm ensures proximal hemorrhage control and accurately predicts the primary source of hemorrhage. We propose a new algorithm that will be more inclusive. A zone 3 REBOA should not be performed when a zone 1 is indicated by the algorithm as 100% of these patients exsanguinated. MOF, perhaps from visceral ischemia in patients with an inappropriate zone 1 REBOA, may have been prevented with zone 3 placement or limited zone 1 occlusion time. LEVEL OF EVIDENCE: Level III

Advanced cotton fibers exhibit efficient photocatalytic self-cleaning and antimicrobial activity

Functional cotton fibers have a wide range of applications in domestic, commercial, and military settings, and so enhancing the properties of these materials can yield substantial benefits. Herein, we report the creation of functional fibers that are self-cleaning, anti-microbial, and protective against UV radiation. A uniform, and high surface area films of TiO2 were deposited on cotton fibers and gold/silver nanoparticles were directly incorporated on the nanostructured TiO2 surface. The synthetic method is simple and the produced TiO2 film is homogenous and the nanoparticles were shown to be effectively distributed on the surface using a simple photocatalytic reduction method. The Ag/Au-TiO2 coated fibers was morphologically characterized using atomic force microscopy (AFM) and scanning electron microscopy/energy dispersive X-ray spectroscopy (SEM/EDS), and the self-cleaning properties of noble metal nanoparticle/TiO2 coated fibers were demonstrated by repeated staining followed by exposure to simulated solar light. The 1 mM Ag-TiO2 coated fabric was observed to have the largest improvement in rate of stain extinction compared to the untreated fibers with a methylene blue stain, and the 1 mM Au-TiO2 coated fibers were observed to have the largest improvement versus untreated fibers when stained with Congo red. The fibers maintained consistent photocatalytic activity over multiple cycles, and the resistance of the Ag/Au-TiO2 coated cotton to degradation was verified using Fourier transform infrared spectroscopy (FTIR). An efficient anti-microbial activity of the fibers was confirmed by exposure of the fibers to bacterial culture (Escherichia Coli) and direct observation of antimicrobial activity

Combining community wastewater genomic surveillance with state clinical surveillance: A framework for SARS-CoV-2 public health practice

Study objective: To garner a framework for combining community wastewater surveillance with state clinical surveillance that influence confirmation of SARS-CoV-2 variants within the community, and recommend how the flow of such research evidence could be expanded and employed for public health response. Design, setting, and participants: This work involved analyzing wastewater samples collected weekly from 17 geographically resolved locations in Louisville/Jefferson County, Kentucky from February 10 to November 29, 2021. Genomic surveillance and RT-qPCR platforms were used as screening to identify SARS-CoV-2 in wastewater, and state clinical surveillance was used for confirmation. Main results: The results demonstrate increased epidemiological value of combining community wastewater genomic surveillance and RT-qPCR with conventional case auditing methods. The spatial scale and temporal frequency of wastewater sampling provides promising sensitivity and specificity to be useful to gain public health screening insights about community emergence, seeding, and spread. Conclusions: Better national surveillance systems are needed for future pathogens and variants, and wastewater-based genomic surveillance represents opportune coupling. This paper presents current evidence that complementary wastewater and clinical testing is enhanced cost-effectively when linked; making a strong case for a joint public health framework. The findings suggest significant potential for rapid progress to be made in extending this work to consider pathogens of interest as a whole within wastewater, which could be examined in either a targeted fashion as we currently do with SARS-CoV-2 or in terms of a global monitoring of all pathogens found, and developing evidence based public health practice to best support community health

Integrated and Open Interpreter Education: The Open Educational Resource Reader and Workbook for Interpreters

https://digitalcommons.wou.edu/facbooks/1001/thumbnail.jp