Cache Aware Mapping of Streaming Applications on a Multiprocessor System-on-Chip

Efficient use of the memory hierarchy is critical for achieving high performance in a multiprocessor system- on-chip. An external memory that is shared between processors is a bottleneck in current and future systems. Cache misses and a large cache miss penalty contribute to a low processor utilisation. In this paper, we describe a novel cache optimisation technique to reduce instruction and data cache misses for streaming applications. The instruction and data locality are improved by executing a task multiple times before moving to the next task. Furthermore, we introduce a dataflow model that is used to trade-off the number of cache misses against end-to-end latency and memory usage. For our industrial application, which is a Digital Radio Mondiale receiver, the number of cache misses is reduced with a factor 4.2

Neonatal sepsis is mediated by maternal fever in labour epidural analgesia

The association between neonatal sepsis and labour epidural analgesia (EA) was evaluated. In a retrospective matched case-control study, 453 women delivering with EA (EA group) were matched on parity with 453 women with deliveries without EA (non-EA group). Significantly more neonates born in the EA-group had fever >= 38.0 degrees C (11.6% vs 1.8%,

Comparison of an Æthereal network on chip and traditional interconnects: two case studies

The growing complexity of multiprocessor systems on chip make the integration of Intellectual Property (IP) blocks into a working system a major challenge. Networks-on-Chip (NoCs) facilitate a modular design approach which addresses the hardware challenges in designing such a system. Guaranteed communication services, offered by the Æthereal NoC, address the software challenges by making the system more robust and easier to design. This paper describes two existing bus-based reference designs and compares the original interconnects with an Æthereal NoC. We show through these two case study implementations that the area cost of the NoC, which is dominated by the number of network connections, is competitive with traditional interconnects. Furthermore, we show that the latency in the NoC-based design is still acceptable for our application

Comparison of an Æthereal network on chip and traditional interconnects: two case studies

The growing complexity of multiprocessor systems on chip make the integration of Intellectual Property (IP) blocks into a working system a major challenge. Networks-on-Chip (NoCs) facilitate a modular design approach which addresses the hardware challenges in designing such a system. Guaranteed communication services, offered by the Æthereal NoC, address the software challenges by making the system more robust and easier to design. This paper describes two existing bus-based reference designs and compares the original interconnects with an Æthereal NoC. We show through these two case study implementations that the area cost of the NoC, which is dominated by the number of network connections, is competitive with traditional interconnects. Furthermore, we show that the latency in the NoC-based design is still acceptable for our application

Management of late-preterm premature rupture of membranes: the PPROMEXIL-2 trial

Item does not contain fulltextOBJECTIVE: The evidence for the management of near term prelabor rupture of membranes is poor. From January 2007 until September 2009, we performed the PPROM Expectant Management versus Induction of Labor (PPROMEXIL) trial. In this trial, we showed that in women with preterm prelabor rupture of membranes (PPROM), the incidence of neonatal sepsis was low, and the induction of labor (IoL) did not reduce this risk. Because the PPROMEXIL trial was underpowered and because of a lower-than-expected incidence of neonatal sepsis, we performed a second trial (PPROMEXIL-2), aiming to randomize 200 patients to improve the evidence in near-term PPROM. STUDY DESIGN: In a nationwide multicenter study, nonlaboring women with PPROM between 34 and 37 weeks' gestational age were eligible for inclusion. Patients were randomized to IoL or expectant management (EM). The primary outcome measure was neonatal sepsis. RESULTS: From December 2009 until January 2011, we randomized 100 women to IoL and 95 to EM. Neonatal sepsis was seen in 3 neonates (3.0%) in the IoL-group versus 4 neonates (4.1%) in the EM group (relative risk, 0.74; 95% confidence interval, 0.17-3.2). One of the sepsis cases in the IoL group resulted in neonatal death because of asphyxia. There were no significant differences in secondary outcomes. CONCLUSION: The risk of neonatal sepsis after PPROM near term is low. Induction of labor does not reduce this risk